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Five Potential Nootropic Benefits of Noopept


5 Potential Nootropic Benefits of Noopept

Five Potential Nootropic Benefits of Noopept

Noopept is a nootropic compound similar to the popular piracetam. Also known as N-phenylacetyl-L-prolyglycine ethyl ester, noopept was originally developed to imitate the reaction between piracetam and vasopressin. While it does not technically contain a racetam molecule, noopept is often grouped within the racetam family of nootropics thanks to its potentially similar benefits.

Noopept Chemical Structure

Noopept Structure

Studies have shown that noopept may provide benefits to various components of your cognition. Let’s take a look at five potential noopept benefits.

What does Noopept do? 

1. Noopept may benefit your memory.

Studies suggest that noopept may actively improve memory, particularly in terms of consolidation and retrieval. This essentially means that noopept may help with both long term and short term memory, along with overall faster recall.

Other studies point to noopept’s potential for increased levels of nerve growth factor. Nerve growth factor, by acting on the TrkA receptor, plays an important role in the process by which your brain and body promote the growth and specialization of new neurons and synapses, both of which are tied to improved long term memory.

2. Noopept may benefit your brain.

Some scientists and doctors suggest that the main purpose of noopept is its general neuroprotective qualities. This means that it may protect the brain and prevent damage to it, particularly during oxidative stress, physical trauma, or other various states of cognitive trauma. In some cases, this may even mean potenetially reversing damage that your brain has sustained. These neuroprotective effects have been shown in research animals.

3. Noopept can potentially boost your energy and mood.

People who take noopept often anecdotally report a boost in mental energy, comparable to lifting a brain fog. This can lead to clearer, more open thoughts and less struggle when performing cognitive processes.

Noopept may also stimulate serotonin receptors. Serotonin is a neurotransmitter with receptors centered around the brain, bowels, and individual blood platelets. Along with regulating transmitting nerve impulses, constricting muscles, and regulating certain components of your internal clock, serotonin is most known for providing feelings of wellbeing and general happiness. By potentially stimulating serotonin production, noopept may help give your mood a boost.


It is believed Noopept may also elevate mood due to its potential ability to reverse atrophy in the Hippocampus. It is suggested it does this by increasing both nerve growth factor and brain derived neurotrophic factors.

4. Noopept may promote healthy stress levels

Noopept may promote feelings of well-being by increasing the amount of dopamine in the cerebral cortex. Dopamine is another neurotransmitter that is involved in a variety of functions in the body, including motivation, reward, attention, and mood. By supporting the amount of dopamine in your body, noopept may also support healthy stress levels. 

Noopept may support healthy stress levels by modulating neuronal activity in the CA1 region of the Hippocampus. This area of the brain, when it becomes overactive, can put in motion a cascade of neuronal effects that compound and result in manifestations of stress. Noopept, appears to activate specialized neurons in the CA1 region, called inhibitory interneurons, which slow the activity of Pyramidal neurons in the CA1 region.

5. Noopept may benefit your learning abilities.

Along with recalling information, noopept may help you acquire new information. The nootropic may help sensitize Acetylcholine receptors. Acetylcholine is considering the learning neurotransmitter, thus having more sensitive receptors for this neurotransmitter, could lead to enhanced learning capacity. 

Acetylcholine Structure

Acetylcholine Structure

Noopept may also potentially activate AMPA and NMDA receptors, which play a major role in learning and memory. Furthermore, its effects on nerve growth factor and brain derived neurotrophic factor could also enhance learning capacity.

Noopept CAS: 157115-85-0

Also Known As: N-phenylacetyl-L-prolyglycine ethyl ester