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Curcumin is the yellow colored pigment in Turmeric and most commonly known as a spice used in curry. Curcumin is the bioactive part of Turmeric and is concentrated at the stems of the cucuma longa plant.
While a popular dietary supplement, many do not know that Curcumin has weak oral bioavailability. This is partly due to its rapid metabolism and its low intestinal absorption rate. Furthermore, Curcumin is also fat soluble so ingesting Curcumin for its reported health benefits on its own won’t have great absorption in the body. One way absorption can be improved by pairing it with a fat source such as fish oil.
Piperine is extracted from the Piper Nigrum plant which produces white and black pepper. Research has found that Piperine increases the absorption of some supplements that are consumed orally such as Curcumin.
The most cost-effective option for increasing the bioavailability of a Curcumin supplement is by pairing Curcumin with Piperine.
Nootropics Depot recommends a Curcumin and Piperine ratio of 1000mg of Curcumin to 6mg of Piperine.
Piperine is a component of black pepper. Studies have found that the combination of Curcumin with Piperine significantly improves the bioavailability of Curcumin. Some research has found that Piperine may increase the bioavailability of Curcumin as much as 20-fold.
Curcumin seems to increase the synthesis of DHA and raise concentrations in the brain and liver. DHA is a chain of omega-3 fatty acid that is critical for brain protection and development. In vitro studies of Curcumin have shown protective properties against glutamate induced cell death. This is believed to be due to a modification to the NMDA receptors or the preserving of BDNF concentrations. A human study looking at the effectiveness of bioavailable curcumin found that 80mg of bioavailable curcumin consumed daily resulted in about a 40% increase in circulating nitric oxide.
Curcumin with Piperine reportedly promotes organ health as this combination may allow Curcumin to increase the absorption of glutathione, which is known for its cellular health benefits in the liver. An in-vitro study suggests that Curcumin + Piperine may support cellular health as well. Turmeric has traditionally been used to support joint stiffness and discomfort. Additionally, one study on athletes found that a Curcumin and Piperine supplement significantly supported muscle recovery in athletes after a workout.
As a dietary supplement, take 2 Curcumin with Piperine capsules daily.
To gain more insight, see the Curcumin + Piperine reviews and experiences below.
Nootropics Depot offers 60 count and 180 count jars of high quality Curcumin with Piperine capsules. Nootropics Depot’s Curcumin with Piperine capsules have been lab tested and verified for both product purity and identity.
Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.