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Panax ginseng is part of the Araliaceae family and is also known as Korean ginseng, True ginseng, and Mountain ginseng. Panax ginseng is native to Asia and has been traditionally used for medicinal purposes for over 2000 years and is also considered very valuable among medicinal plants in Asian countries. The name ‘panax’ means “all healing” and may have sprouted from the belief that the properties of ginseng can serve many purposes for the human body.
Panax ginseng extract carries a mix of active components known as ‘ginsenosides’. Ginsenosides are usually given credit for many of Panax ginseng’s effects. Countless studies focus on the research of ginsenosides instead of whole ginseng extract. Of the many ginsenosides in Panax ginseng, Rb1, Rg1, Rg3, Rd, and Re are the most frequently researched.
While ginsenosides Rg1 and Re are found in the roots, Rg1 and Re are found in much higher concentrations in the leaves. Overall ginsenoside content in Panax ginseng is higher in the leaves and roots compared to the stem and other parts of the plant. Yet, Re and Rd are the primary ginsenosides in ginseng leaf and are usually found in very high concentrations. Interestingly enough, Re and Rd ginsenosides seemed to help inhibit cell apoptosis in some studies. Research found that Panax ginseng leaf extract promoted cardiovascular and cellular health in rats. A small research study on humans found that panax ginseng extract seems to promote feelings of well being as well as cognitive function. However, this was only seen primarily in stressed individuals and harder to see in unstressed individuals.
Some research suggests that there may be a few panax ginseng benefits for men. Male rats that added 5% Panax ginseng extract to their diets experienced a rise in blood testosterone levels. While a separate study showed an increase in protein synthesis in mice.
At 1g/kg, Panax ginseng orally administered to rats seemed to elevate GDNF mRNA after about 2 months and also found that ginsenosides Re, Rb1, Rg1 Rb2 are agonists of the GABA(A) receptor and Rc is an agonist for the GABA(B) receptor. In addition, Rb1 and Re ginsenosides have been reported to be androgen receptor agonists through stimulation of Nitric Oxide production via nitric oxide synthase.
Yes, this Panax Ginseng Leaf Extract contains 40-45% ginsenoside content.
Want to learn more about Panax Ginseng leaf extracts? Check out our panax ginseng blog here.
Nootropics Depot offers a Panax Ginseng sample pack featuring GS15-4, our leaf extract and our root extract that you can trial before you commit to purchasing a full size jar.
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As a dietary supplement, take 200mg of Panax ginseng extract powder 1-3 times daily.
To gain more insight, see the Panax ginseng leaf extract reviews and experiences below.
Nootropics Depot offers 15 gram and 30 gram jars of high quality Panax Ginseng leaf extract powder. Nootropics Depot’s Panax Ginseng has been lab-tested and verified for both product purity and identity.
Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
After months trying some adaptogens* individually, this Panax Ginseng Leaf Extract is simply the best for me. Although I'm only using 200 mg once a day, I'm guessing upping to 400–600 mg might be slighly better. It helps by reducing a bit my sleep inertia and fatigue from simply daily activities.
Since the leaf has absurdly high levels of the ginsenoside Rg1 & also high Re (MisterYouAreSoDumb, 2016, reddit), based on some studies about both acting on glucocorticoid receptors (GR), I'd say they positively regulate the GR (agonism is established) and/or increase a naturally low HPA axis responsiveness.
* Ashwagandha (Normal, KSM-66, Sensoril), Bacopa monnieri, Panax Ginseng GS15-4 (ND), Relora and Rhodiola rosea (3% salid.) (ND);
P.S.: I have Idiopathic Hypersomnia (IH) & naturally lower than normal salivary cortisol levels throughout the day (fixing it doesn't fix all my IH).
P.P.S.: ND Admin, I'd like to suggest selling a 60 or 125 g bottle if it's reasonable. Thanks! Vítor Campos on 28th Jan 2019
Good product, excellent value. Will likely order again. Unknown on 22nd Sep 2018
Quality and package is great, but this one did not agree with me. Unlike the root extract versions, the leaf extract one made me drowsy. Unknown on 18th Oct 2017
This is a great energy enhancing product and gives the energy effect most people are actually seeking in Ginseng, I think. It tastes exactly like the very strong Korean ginseng's I used to be able to source and is definitely swimming with the active ingredient! I combine with the GS15-4 stuff for a more balanced feel. Jim on 7th Nov 2016