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Red Reishi, or Lingzhi (Ganoderma lucidum), is a polypore mushroom that is soft, corky, and flat; with a conspicuous red-varnished, kidney-shaped cap and, depending on specimen age, white to dull brown pores underneath. The Lingzhi mushroom was first used by the Chinese in the Han Dynasty (206 BCE-220 CE), and has a long history of use in traditional Chinese medicine. It was written about extensively in Chinese classical texts.
Studies have shown that Reishi extract significantly inhibited all four types of allergic reactions, including positive effects against asthma and contact dermatitis and effectively used in treating stiff necks, stiff shoulders, conjunctivitis (inflammation of the fine membrane lining the eye and eyelids), bronchitis, rheumatism and improving "competence" of the immune system without any significant side-effects. A water extract from Reishi mycelium significantly increased the threshold for psychomotor seizures in mice. Mycelial extracts also confer anti-inflammatory activity as evidenced by inhibitory activity of lipopolysaccharide (LPS)-induced nitric oxide (NO) production in murine macrophage-like cells. The use of Ganoderma lucidum has also been explored as a complementary adjunct treatment in patients undergoing chemotherapy treatment. A recent meta-analysis of five randomized control trials showed that patients responded more positively when given G. lucidum alongside their chemotherapy regimen, and the studies also showed that patients had improved immune functions that was measured by their elevated levels of immune response cells. Several compounds in Ganoderma lucidum have been studied for apoptotic activity in colon cancer cells, antiproliferative effects in ovarian cancer cells, and induction of apoptosis in human gastric carcinoma cells.
Ganoderma lucidum produces a group of triterpenes, called ganoderic acids, which have a molecular structure similar to steroid hormones. It also contains other compounds often found in fungal materials, including polysaccharides (such as beta-glucan), coumarin, mannitol, and alkaloids. Fungal immunomodulatory proteins (FIPs) are bioactive ingredients within genera Ganoderma that have immune building properties. FIPs stimulate different cells and cellular components that enable immune response. Some of the molecules and cells that FIPs influence include T and B lymphocytes, natural killer cells, macrophages, and regulation of human monocyte DCs. Improved function of these cells will promote cytokine expression such as IL2, IL-4, and IFN-gamma which will support lymphocyte proliferation, immune cell initiation, and tumor inhibiting factors. Immunostimulation from FIPs could cause increased expression of costimulatory molecules and major histone complexes (MHC) which help to create a pathway for immune response to take place.
Nootropics Depot has partnered with Nammex to offer these certified Organic whole fruiting body extracts, with not only testing to verify the percentage of active beta glugcans, but verififaction that starch content is low, and that there are no pesticide residues. One of the biggest conroversies in the medicinal mushroom industry today is the use of mycelium on grain extracts. Mycelium is to a mushrom like what roots are to a tree. When grown properly, they will form whole fuiting bodies; which are called mushrooms. However, to save money, most US producers of medicinal mushroom extracts today grow the mycelium on a bed of grain, like rice. To speed up production, and to make the end product cheaper to produce, these manufacturers grind up the mycelium and grain together, before allowing them to form whole fruiting bodies. The issue with that is that mycelium is not a mushroom, just like the roots of a tree are not a tree. The beneficial compounds in these mushroom species are all studied with relation to their fruiting bodies. The FDA even states that mycelium is not allowed to be called "mushrooms." However, many of the biggest brands today thwart that FDA guideline, and put out a cheaply-made, mislabeled, and ultimately inneffective products. They hide this fact by standardizing to "polysaccharides" instead of "β-Glucans." Well guess what shows up as polysaccharides in the traditional testing? Carbohydrates! Yes, the very carbohydrates from the rice used to grow the mycelium is used as a measure of the active ingredient in these substandard extracts. When you are buying one of the major mushroom extracts on store shelves today, you are buying a bunch of ground up rice mixed in with mycelium! It's a scam! This is why we decided to partner with Nammex. We are selling only certified Organic whole fruiting body extracts, which have been tested for not only the active β-Glucans, but to ensure the strach content is low; to prove what you are getting is actual mushroom, not ground up rice. You will know right away how big of a difference it is. You can even go to the store right now, and pick out one of the major mushroom brands. Mix the "mushroom" powder into some water, and ad a drop of iodine. It will quickly turn a dark purple/blue, indicating high amounts of starch. You'll immediately see how big of a scam it is, and just how many "trusted" brands are in on it!
Beta-Glugan (β-Glucan) content: 35%
Product contains either a 30g or 60g jar of Certified Organic Red Reishi (Lingzhi) mushroom extract.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
You may also be interested in Red Reishi Mushroom Extract Capsules.
I've been trying reishi from a number of different sources for around a year. This extract is my favorite. It is not as bitter as some more potent extracts, but has a much higher beta glucan amount. I just got nootropic depots 4:1, which is much more bitter and higher in tritepenes. So that is good for a couple days a week. But I really like using this extract for daily use. My current schedule is this extract every day, then the 4:1 two to three times per week. I'll have to try out some of the other mushroom extracts. If they are as good as the reishi I will be a happy person. Gabe Lau on 6th Aug 2016
I'm just glad to have a real reishi extract. Please keep this the same ND. Runs your immune system. Reduces irritability. Clears up insomnia, especially when combined with magnesium. Increases wisdom over the long term because of the way you emotionally respond to stress. Best used everyday. Mark on 29th Jun 2016
I started taking this along with the Lion's Mane extract (also from ND) about 3 days ago. The effects are subtle, but the way I would describe it is it makes me feel a bit more "normalized." It feels like my mood is more productive and stable with a tendency to be more positive.
I have been a, for the most part, daily phenibut user for the past two years or so taking anywhere from 1.5 to 2.5 grams. When I take these mushroom extracts I almost forget to take phenibut because I feel quite stable and anxiety-free. I have a bit more testing to do in that regard.
I have known for a long time the health benefits of medicinal mushrooms, but for some reason I never committed to a supplement form for them. I've made reishi tea from whole reishi caps, and I had great results but it wasn't very cost effective. I am very satisfied with Nootropics Depot's mushroom extracts. I also take their Cordyceps extract as well. You can actually taste the mushroom in these extracts. The powder is absolutely high quality and pure. I'm very thankful for ND for offering a line of medicinal mushrooms. Phil on 27th Jun 2016