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Triacetyluridine (also known as TAU) is a uridine supplement that is occasionally used as a nootropic supplement. Uridine is a precursor of ribonucleic acid (RNA) and supports healthy functioning of the central nervous system.
Research has found that Triacetyluridine activates the P2Y2 brain receptors. These receptors trigger activity from Nerve Growth Factor (NGF). P2Y2 receptors supports healthy inflammatory responses and protects against neurotoxicity even when the mitochondria may not be functioning properly. Triacetyluridine enhances functioning in synaptic connections and neurons are able to communicate faster and more efficiently, thus supporting the idea that Triacetyluridine supplements may support brain health and cognitive function.
Research has shown that Triacetyluridine increases the bioavailability of uridine in the body. Some studies have shown that it has potential to increase neuroplasticity by raising the brain’s levels of nerve growth factor as well as support brain health. Typical uridine supplements tend to have low bioavailability and have weak solubility in fats. On the other hand, triacetyluridine has superior lipid solubility and bioavailability compared to uridine.
Triacetyluridine and uridine tend to work well with lipids and phospate groups. Triacetyluridine tends to behave synergistically with choline and fish oil to enhance mood. In fact, Harvard Medical School combined DHA (docosahexaenoic acid) and Omega-3 fatty acids with Triacetyluridine and found that the combination created a healthy emotional outlook in subjects.
Triacetyluridine is still being researched for its ability to promote feelings of well-being. A 6-week clinical study on human subjects concluded that TAU “improved overall mood of subjects”. Triacetyluridine is about 4-7 times more potent than uridine monophosphate. Triacetyluridine is also lipid soluble so it can only be taken orally and not sublingually. However, Triacetyluridine absorbs well with food in the stomach whereas with uridine monophosphate, the absorption with food is up for debate. Triacetyluridine is typically dosed between 25 and 50mg.
A study looking at the relationship between uridine and omega-3 fatty acids when administered together found a synergistic effect in rats. The rats’ mobility rate increased. Both of these compounds administered together allowed for reduced dose sizes of each to achieve the desired effect.
As a dietary supplement, take 25mg of Triacetyluridine once daily.
To gain more insight, read the Triacetyluridine reviews and experiences below.
Nootropics Depot offers 10g, 25g or 50g jars of high quality Triacetyluridine Powder. Nootropics Depot's Triacetyluridine has been lab-tested and verified for both product purity and identity.
Attention: This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.
I've never taken UMP (yet), but started taking 25mg of TAU four days ago in the morning with my am dose of Fish Oil on an otherwise empty stomach.
I tell you what, it's like a light switch was flipped in my brain. After years of alcohol and benzo abuse, I felt depressed, brain dead, and unable to focus. Even after 1.5 years clean.
I'm only four days into this and I feel better than I have in a decade. Motivation, focus and critical thinking are now finally possible again.
I may start to add a small dose of a choline source in a week, depending on how it goes. I think many folks dose way too high on their choline source, causing brain fog. I'm doing great on this and fish oil alone right now.
I could feel this the first day, and on day #4, I'm noticing continued improvements. I tried all the racetams sold here (with and without a choline source) and this has a much more significant effect for me. Very interested to see how adding a racetam will be in a few weeks will be, now that the lights are turning back on upstairs.
I'm down from 6-8 cups of coffee a day to only 2. Also noticed, that I vape VERY infrequently now. I could see this as an effective tool for folks wanting to stop vaping or smoking as well.
Kudos to ND for offering uridine in this form. Not sure there's anywhere else that sells it in the TAU form. I will be trying UMP at some point, but am getting such great results from this currently, that I'm in no hurry to do so.
The 10g bottle has 400 doses if you use the recommended 25mg amount. I've only been using it once/day and it's plenty for me. I'm definitely ordering another 10g or maybe even 25g tub of this to have on hand for future use. Sam on 4th Dec 2018
I like this because I can take very little so it lasts me a very long time compared to your uradine monohydrate. I can definitely notice how he dopamine receptors are up regulated because coffee is 100 times more potent now I had to cut my usage of coffee almost to nothing because it was too stimulating. So I have no doubt this product works! Richard H on 1st Dec 2018
This is a very good product with a potency stronger than Uridine Monophosphate.. it is still very effective, and high quality, thanks to Nootropics Depot! Unknown on 6th Oct 2018
I take it in the morning before leaving for work, and it helps push me through the day. Jeff on 12th Sep 2018
Tested out exactly as it sais it is without cutting agents which isn't always easy to find nowadays. Great business, fast shipping and good people. Very professional Paul Szeto on 13th Jan 2018
I prefer UMP, much more stronger results Unknown on 13th Dec 2017
Thanks ND for shipping to Brazil! About triacetyluridine, gives me brain energy, its cool to combinated with DHA, PS and coffe. Unknown on 16th Sep 2017
And phenylpiracetam. With those 3 powers combined(the triforce if you will) I was like Elton John..............
Rocket Maaaaaaaaaaaaan Phil Grandin on 22nd Feb 2017
Every time I make a capsule of this and take DHA fish oil (also from nootropicsdepot) I notice myself feeling tingly and bright later, not too unlike a smaller dose of adderall, tbh. At least, it counters my.night meds in, while enjoyable, a rather unproductive manner. I can see why this is used for cognitive enhancement for sure.. srubek on 28th Dec 2016
give me energy,mood and focus ,I recommend ! grzegorz(chyren) on 16th Oct 2016