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Black Seed Extract Powder | Nigella sativa

Standardized to 5% or 10% thymoquinone for immune support, metabolic wellness, and healthy neurological function.

(18 Reviews) Write a Review

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Black Seed Extract Powder | Nigella sativa

Standardized to 5% or 10% thymoquinone for immune support, metabolic wellness, and healthy neurological function.

(18 Reviews) Write a Review

View All Reviews

Available in multiple forms! Click Here for:
  • Standardized to 5% or 10% Thymoquinone
  • HPLC Tested for Bioactive Content
  • Supports Immune and Metabolic Function
  • Backed by Centuries of Traditional Use

3rd Party Lab Tested & Verified

See Why ND Black Seed Is The Best

Evidence-Based, Fact-Checked

Updated On: 05/23/2026

$15.99 - $39.99

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ATTENTION: This product does not include a scoop. Learn more

Benefits

When You'll Notice Effects

2-3 Weeks (With Immediate Effects)

Black Seed Extract (Nigella sativa) supports immune function, comfort, metabolic health, and brain health by promoting healthy memory and mood while supporting neurological function.

  • Immune
  • Pain Support
  • Metabolism
  • Cognition

Why ND Black Seed Extract?

A Black Seed Extract standardized to 10% thymoquinone
test

How To Take

Dose
Dose

200mg (Per Serving)

Timing
Timing

Flexible

How to Take
How to Take

With Or Without Food

Frequency
Frequency

1 Time Daily

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  • About Nigella Sativa (Black Seed) Extract

    Nigella sativa black seed extract with 5% and 10% thymoquinone in wooden scoop.

    Black Seed Extract from Nigella sativa is a concentrated powder standardized to contain a minimum of 5% or 10% thymoquinone, the key bioactive compound in these ancient seeds. Black seed supports immune function, promotes healthy metabolic processes, and helps maintain cognitive wellness through its rich profile of essential oils and nutrients.

    Our Black Seed Extract Story

    Black seed's versatility and thousands of years of traditional use across Southern Europe, North Africa, and Southwest Asia drew us to this remarkable botanical. Many suppliers offer basic black seed powders with inconsistent potency, so we developed a standardized extract that delivers reliable levels of thymoquinone, the primary compound responsible for black seed's wellness benefits.

    We focus on the essential oil fraction that makes up only 0.4% to 2.5% of the seed's weight but houses the most bioactive compounds including thymoquinone, dithymoquinone, thymohydroquinone, and carvacrol. By offering both 5% and 10% thymoquinone standardizations, we give you the flexibility to choose the potency that best fits your wellness goals, whether you're new to black seed or looking for a more concentrated option.

    Benefits

    • Supports Healthy Immune Function: The natural compounds in Black Seed Extract support the body's antioxidant defenses, helping you feel more resilient during stressful periods or seasonal changes.
    • Supports Comfort: Black Seed Extract provides gentle, natural support for physical comfort through its bioactive compounds including thymoquinone and essential oils.
    • Supports Metabolic Function: Black Seed Extract promotes healthy metabolic function and keeps cellular activity running smoothly, supporting your body's natural energy production processes.
    • Supports Brain Health: Regular users report sharper thinking, improved memory, and greater mental clarity, helping you stay more focused at work and present in everyday life.

    Black Seed Extract also supports a positive mood and helps promote a balanced stress response with its gentle approach to promoting emotional balance. The vitamins, minerals, and essential oils naturally present in Nigella sativa provide nutritional support from within, contributing to overall vitality and helping you maintain an active, engaged lifestyle throughout the years.

    Icons highlight Nigella sativa benefits for cellular, cognitive, metabolic, and immune health.

    Quality and Standardization

    • Standardized Thymoquinone Content: Every batch of our Black Seed Extract is rigorously tested and standardized to deliver either 5% or 10% thymoquinone, ensuring consistent potency and reliable results with each serving.
    • Third-Party Laboratory Testing: We provide complete transparency through third-party test results and detailed sourcing information, so you know exactly what you're getting without any surprises.
    • Quality-First Manufacturing: Our rigorous testing protocols and attention to detail ensure that every batch meets our exacting standards, giving you confidence in your supplement choice.
    • Transparent Process Documentation: We openly share our testing methodology and sourcing practices because we believe you deserve to know where your supplements come from and how we test them.

    Nigella sativa flower and black seeds shown as digestive and immune support supplement.

    Mechanism of Action

    • Thymoquinone Pathway Support: The primary bioactive compound thymoquinone interacts with key cellular pathways to support a healthy inflammatory response and cellular defense mechanisms throughout the body.
    • Antioxidant Response Support: Multiple aromatic compounds including p-cymene and carvacrol work together to support antioxidant activity and activate the body's natural antioxidant systems, supporting protection against oxidative stress.
    • Immune System Support: Black seed extract helps support healthy cytokine levels and T cell activity, supporting healthy immune responses to maintain optimal immune function.
    • Metabolic Pathway Support: The bioactive compounds support healthy metabolic processes by promoting healthy lipid profiles and supporting healthy blood sugar levels within the normal range through multiple enzymatic pathways.
    • Supports Neurological Health: Essential oils from Nigella sativa provide support for neural tissue, helping maintain healthy cognitive function and stable mood through various brain pathways.

    Bar graph compares thymoquinone levels in Nootropics Depot black seed extract versus competitors.

    Overview of the Science

    Black Seed Extract (Nigella sativa) is backed by a growing base of research highlighting its support for many aspects of general wellness. The main component, thymoquinone, along with related actives like dithymoquinone, thymohydroquinone, p-cymene, and carvacrol, supports healthy immune function by promoting balanced cytokine production and encouraging the activity of T cells [1]. These compounds also provide antioxidant support, assisting in the neutralization of free radicals and helping to maintain healthy cellular environments.

    Scientific studies have explored Nigella sativa's role in supporting comfortable joint and muscle function, as well as supporting a healthy inflammatory response through its combination of antioxidants and essential oils. Research suggests Black Seed Extract supports healthy metabolic function, promoting balanced lipid levels and healthy glucose metabolism. The seed's nutritional profile—including vitamins, minerals, and essential oils—works together to foster healthy cellular activity and maintain wellbeing on multiple levels.

    Research continues to investigate its influence on cognitive performance, learning, and memory, with promising early findings around its ability to support healthy mood and mental clarity. Many users also appreciate how these effects contribute to a focus on maintaining overall vitality and general wellness.

    [1] Bin Sayeed MS, Shams T, Hossain SF et al. Nigella sativa L. (Ranunculaceae): A review of its traditional uses, phytochemistry, pharmacology and toxicology. Pak J Pharm Sci. 2012;25(3):553-560.

    Nootropics Depot Nigella sativa capsules support mood, cognition, cellular, and metabolic wellness.


    Click here to read the Research Snapshot

    Ingredients

    Black Seed Extract (Nigella sativa):

    • Nigella sativa seed extract
    • Standardized to minimum 5% Thymoquinone
    • 200mg per serving

    Our Black Seed Extract is standardized to a minimum 5% thymoquinone content, ensuring consistent potency of this key bioactive compound. Thymoquinone is the primary active constituent responsible for many of black seed's wellness benefits, including immune support and antioxidant activity. This standardization level guarantees you receive a reliable dose of the most important compound in every serving, making our extract far more potent and predictable than basic whole seed powders.

    Superior black seeds on a rustic cloth with wooden spoon and sourcing, manufacturing, and lab testing notes.

  • Lab Testing Results / Certificate of Analysis (COA)

  • Frequently asked questions

    1. Should I choose 5% or 10% thymoquinone Black Seed Extract?

      The 10% thymoquinone extract offers double the concentration of the primary bioactive compound compared to the 5% version, making it more potent for immune support and metabolic wellness. If you're new to black seed extract, starting with the 5% version allows you to assess your tolerance before moving to the higher concentration. Both extracts provide the same benefits, with the 10% requiring a smaller serving size to achieve similar thymoquinone intake.

    2. How much Nootropics Depot Black Seed Extract should I take daily?

      Our Black Seed Extract powder requires precise measurement with a milligram scale since no scoop is included. The recommended daily dose depends on which concentration you choose - either the 5% or 10% thymoquinone standardized extract. We recommend using our milligram scale available at nootropicsdepot.com/nootropics-depot-milligram-scale-nds-201/ for accurate dosing.

    3. Can Black Seed Extract cause stomach problems or acid reflux?

      Black Seed Extract is generally well-tolerated and can be taken with or without food, which helps minimize potential stomach upset. Some people may experience mild digestive discomfort when first starting any new supplement, but this typically resolves as your body adjusts. If you have a sensitive stomach, taking our Black Seed Extract with food may help reduce any initial digestive sensitivity.

    4. Can I stack Black Seed Extract with other nootropics safely?

      Yes, our Black Seed Extract stacks well with most nootropics and supplements since it works through different pathways focused on immune support and metabolic function. We recommend starting with our standard dosing and monitoring how you feel when combining with other supplements.

    5. What is Black Seed oil good for?

      Black seed oil supports healthy immune function, promotes metabolic wellness, and helps maintain cognitive health through its rich profile of thymoquinone and essential oils. The oil provides natural antioxidant support and helps the body manage everyday stress and seasonal challenges. Our Black Seed Extract is standardized to contain 5% or 10% thymoquinone, the key bioactive compound responsible for these wellness benefits.

    6. How do you take Black Seed oil?

      Our Black Seed Extract powder can be taken with or without food, offering flexibility in your routine. We recommend using a milligram scale for precise measurement since this powder product doesn't include a scoop - you can find our milligram scale at nootropicsdepot.com/nootropics-depot-milligram-scale-nds-201/. Take it once daily for best results, with full effects typically developing over 2-3 weeks.

    7. What are the benefits of Black Seed oil?

      Black seed oil supports healthy immune function through its antioxidant and antimicrobial compounds, helps manage everyday discomfort naturally, and promotes healthy metabolic processes. Our Black Seed Extract is standardized to contain 5% or 10% thymoquinone, the key bioactive compound responsible for these wellness benefits. The concentrated extract provides more potent support than basic black seed powders through its rich profile of essential oils and bioactive nutrients.

    8. Does Black Seed oil kill parasites?

      Our Black Seed Extract is not intended to kill parasites or treat parasitic infections. Black Seed Extract supports healthy immune function through its natural antioxidant and antimicrobial components, helping strengthen the body's defenses during stressful periods. For any concerns about parasites, we recommend consulting with a healthcare professional.

The Science

What Our Scientific Board Does

The Process

What Do They Do?

  • Review Product Claims
  • Review Cited Research
  • Suggest Changes to Claims
  • Approves Final Conclusions
See The Process

Overview Of The Scientific Evidence

Our Research Snapshot

What Does The Research Show?

Scientific studies show Black Seed Extract aids immunity, metabolic wellness, and brain health, while supporting memory, mood, and neuroprotection.

Understand The Evidence

Trust Through Transparency

Your health matters, which is why we only use the best 3rd party ISO accredited labs and cGMP certified and FDA registered facilities right here in the USA

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Black Seed Extract Powder | Nigella sativa

Black Seed Extract Powder | Nigella sativa

$15.99 - $39.99