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Alpha-GPC, also known as choline alfoscerate and alpha-glycerylphosphorylcholine, is a choline-containing compound found naturally in the brain as well as in small amounts in foods like meat, fish, eggs, and dairy.Alpha-GPC is also a natural phospholipid.
Studies and evidence show that alpha-GPC is considered one of the most efficient sources of choline, a fat-soluble member of the B vitamin complex. This indicates that alpha-GPC may effectively increase concentrations of choline.
Many potential alpha-GPC uses focus on its state as a precursor to acetylcholine, a neurotransmitter that helps the brain send signals to nerves throughout the body. Acetylcholine has been shown to play an important role in memory formation, concentration, logical reasoning, and learning.
Studies indicate that alpha-GPC may support greater synaptic plasticity. This is essentially your brain’s method of adaptation and changing to new information, controlling how your neurons communicate with one another, which results in the process of creating and recalling memories. This may translate to improved retrieval and retention of information. According to research, alpha-GPC may enhance your overall learning capacity and problem solving abilities.
Alpha-GPC is reported to support cognitive health. While there are no randomized, double-blind, placebo-controlled clinical trials showing this is true in healthy adults, anecdotal evidence shows support.
We offer a naturally derived, non-GMO alpha-GPC product manufactured with organic ingredients. Alpha-GPC is also GRAS-affirmed by the FDA, meaning it is Generally Recognized As Safe.
Our Alpha-GPC 99% Powder is a nearly pure product for those who desire full potency, but we also offer Alpha-GPC 50% Powder for those concerned with alpha-GPC’s sensitive hygroscopic nature.
As a dietary supplement, take 300mg of Alpha-GPC once daily.
Alpha GPC and Hygroscopy
Alpha-GPC is a hygroscopic compound, which means it draws in moisture from the air around it, physically changing it from a powder to a gel-like substance when not stored properly. While this hygroscopic effect doesn’t necessarily mean the product has degraded, it is a sign of improper storage. Storing your Alpha-GPC in airtight containers (think vacuum seal) is helpful. While we take steps to ensure this does not happen to your product, should Alpha-GPC 99% arrive with clumps, simply break them up prior to use. Nootropics Depot offers both a 30g and 60g jar.
Why don’t we sell an Alpha-GPC 100% Powder? Alpha-GPC with a purity of greater than 99% will undergo hygroscopy very quickly as soon as it meets the air.
Always discuss the addition of nootropics and supplements with your doctor or another trusted healthcare professional, and stay informed about how a product might affect you--everyone is different.
*Attention: Before consumption, please consult your physician and understand the available research. This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.
Get insight about customers’ experiences by reading our Alpha-GPC reviews below.
ND promptly helped me when I reached out to customer support when ordering. Shipped fast..took like two days to south TX.
I've ordered this product previously but not in such a pure state. Plan to store appropriately, otherwise it will turn to jelly. I take Alpha-GPC before class or before sitting down to study. I have severe inattentive ADD which i am unmedicated for. This product keeps me absorbed in my studies rather than floating in my brain-space. I keep the dose low and sometimes pair with supps like Hup or Uridine. I also like to dose before strength-training. I have not experienced depression from this, even though I am diagnosed manic depressive. Mercedes on 18th Feb 2019
This supplement made me extremely depressed when I took it. There is a theory that cholinergic supplements can cause depression in some people. Perhaps this just isn't for me. I don't hate the supplement or anything, and don't think poorly of it. It's just my reaction to the supplement is all. At least it tastes sweet! miklpls on 14th Jan 2019
If dry storage isn't an issue this is the best value and great quality. Colin Boda on 3rd Aug 2018
nootropics depot, best quality, best education, and indeed best customer service! mohammed on 26th Jun 2018
Alpha -Gpc 99% powder Michael on 24th Jun 2018
The most potent version of choline, and Nootropics Depot does a justice. Unknown on 7th Jun 2018
I find that Alpha-GPC does wonders for me! Nootropics Depot strikes again! Shipping is impeccable with every purchase so far. tawat on 25th May 2018
Perfect. Had no issue with product quality or shipping. Great as always. I only give it 4 stars because it's not my favorite choline source. Long time racetam and stim user, have supplemented with all choline sources. Alpha-GPC is my 2nd fav, with CDP-choline as number 1. I'd get both honestly and see what's best for you. Truda Silberstein on 4th May 2018
Although the 99% can attract moisture, it's worth the tradeoff for me because it dissolves nicely in my mouth (and tastes sweet). I wash it down with water. The 50% gets clumpy and imo is best for making capsules (which I'm too lazy to do since I have so many powdered supps). Matthew Eckert on 10th Apr 2018
Definitely worth the money, as described. Noticeable difference in energy levels when taking. Unknown on 4th Apr 2018