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Alpha-GPC 99% Powder

  • Product Description

    What is Alpha-GPC Powder?

    Alpha-GPC, also known as choline alfoscerate and alpha-glycerylphosphorylcholine, is a choline-containing compound found naturally in the brain as well as in small amounts in foods like meat, fish, eggs, and dairy.


    Alpha-GPC Benefits

    Alpha-GPC is reported to have cognitive and growth-hormone enhancing properties. While there are no randomized, double-blind, placebo-controlled clinical trials showing this is true in healthy adults, anecdotal evidence and some research on rodents shows possibility.

    However, there is a study showing that alpha-GPC benefits those with Alzheimer’s disease or who have had a stroke. In a 1994 Italian multicenter clinical trial of more than 2,000 patients who had recently suffered a stroke, patients were given a higher dose of alpha-GPC (1,000 mg) per day for 28 days followed by a smaller dose (400 mg) three times per day over the next five months. Results showed improvement in cognitive recovery in four measurement scales, three of which showing statistical significance.

    How to Take Alpha-GPC Powder

    For typical use in enhancing athletic and cognitive performance, Alpha-GPC 99% Powder is recommended in one or two doses of 300 mg/day for a total of 300-600mg/day. Start with a smaller dose and find what works best for you. Always discuss the addition of any nootropics compounds with your primary care physician or another trusted health care professional.

    Why Buy Alpha-GPC?

    Other than cognitive benefits and promising efficacy in Alzheimer’s and dementia patients, why buy Alpha-GPC from Nootropics Depot? We offer a naturally derived, non-GMO alpha-GPC product manufactured with organic ingredients. Alpha-GPC is also GRAS-affirmed by the FDA, meaning it is Generally Recognized As Safe.

    Our Alpha-GPC 99% Powder is a nearly pure product for those who desire full potency, but we also offer Alpha-GPC 50% Powder for those concerned with alpha-GPC’s sensitive hydroscopic nature.

    A Note on Hydroscopy

    Alpha-GPC is a hydroscopic compound, which means it draws in moisture from the air around it, physically changing it from a powder to a gel-like substance when not stored properly. While this hydroscopic effect doesn’t necessarily mean the product has degraded, it is a sign of improper storage. Storing your Alpha-GPC in airtight containers (think vacuum seal) is helpful. While we take steps to ensure this does not happen to your product, should Alpha-GPC 99% arrive with clumps, simply break them up prior to use. Nootropics Depot offers both a 30g and 60g jar.

    Why don’t we sell an Alpha-GPC 100% Powder? Alpha-GPC with a purity of greater than 99% will undergo hydroscopy very quickly as soon as it meets the air.

    Always discuss the addition of nootropics and supplements with your doctor or another trusted healthcare professional, and stay informed about how a product might affect you--everyone is different.

    Learn more and read scientific research about alpha-GPC on

    *Attention: Before consumption, please consult your physician and understand the available research. This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.

    Get insight about customers’ experiences by reading our Alpha-GPC reviews below.


  • Product Reviews


    Write A Review

    1. l love it!

      I've tried this product from different companies and found this company to have the best quality; I am on my second order. This product gives me mental clarity and I've noticed it's been helping me shed some weight. on 5th Feb 2017

    2. great product

      great product. will buy again. on 11th Jan 2017

    3. Efficace

      Sans doute un classique des nootropiques, efficaces, au long-terme les effets sont juste incroyable, six mois après prise quotidienne d'alpha-GPC je peut me concentrer des heures et j'ai meilleure mémoire qu'avant, avant je ne tenait pas ma concentration plus de 30 minutes.
      Aucun effets indésirable, adapter à tous.
      on 9th Nov 2016

    4. Delicious

      Tastes great and saves me from Noopept everytime. Thanks on 29th Sep 2016

    5. Thank god for ND!

      Alpha GPC 99% is one of my favorite compounds. When Nootropics Depot stopped carrying it, I was very sad. Sure it clumps more easily than the 50%, but I can deal with that. I am very happy to have a great source of 99% GPC again! on 26th May 2016

    6. Not cognitive enhancing

      This product did nothing for me. on 11th May 2016

    7. Very effective, but hard to work with

      First off, this product is very potent. It's the most effective alpha GPC I have tried from any vendor, and I have tried a lot. However, 99% alpha GPC is very hydroscopic, and clumps up super easily. Nootropics Depot puts in silica and oxygen absorbing packs, which really does help. It does not become an unusable gel like others.However, it still clumps very fast. I find the extra potency of the 99% to be worth it, but many might be surprised. Keep that thing sealed as best you can. If you do not want to deal with the extra hassle, the 50% is probably better for you. on 16th Apr 2016

    8. Best quality choline sourse around! Much better than 50% or CDP-Choline.

      I am very grateful that is selling this product again. A couple years ago when I discovered Alpha-GPC 99% Powder at the old Nootropics Depot store I discovered that I could dissolve 30gm in 120ml (2oz) distilled water with 15gm Calcium Pantothenate and the solution easily remained dissolved. I used 1ml eyedropper to dispense this super choline solution in 2 to 4 ml doses. This solution worked better with my nootropic and neural health stacks than any other choline products. After the old Nootropics Depot disappeared a couple years ago, I was forced to find other vendors of pure Alpha-GPC. I discovered that when I made super Alpha-GPC solution using other vendor products that black stuff started growing in the solution even though I always keep it refrigerated. Now that I’m using Alpha-GPC 99% Powder again the solution remains clear to the last drop. I use 4ml of this solution every morning combined with 200mg Uridine Monophosphate powder and 200mg Dicaffeine Malate and high EPA/DHA fish oil, and also later in the day with racetams or Centrophenoxine. Thanks for bringing this product back! on 7th Apr 2016

    9. I prefer this to the 50%

      Where I live is mostly dry. So I have no problems with the 99% version of Alpha-GPC clumping. I much prefer to have the pure powder without fillers. Alpha-GPC works better for me than CDP too. on 13th Feb 2016

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