About Ginger Supercritical CO2 Extract Capsules

Our Ginger Supercritical CO2 Extract delivers a standardized 10% gingerols and shogaols from the root of Zingiber officinale. Supercritical extraction preserves the volatile bioactive compounds that give ginger its distinctive effects, while ensuring optimal concentration and bioavailability. Each 500mg capsule supports stomach comfort, cognitive function, and healthy inflammatory response.

Our Ginger Extract Story

While ginger has been a staple spice for thousands of years, most commercial ginger products fail to deliver therapeutic concentrations of the bioactive compounds responsible for its benefits. Traditional grinding and heating methods destroy many of ginger's volatile gingerols and shogaols, leaving consumers with products that taste like ginger but lack meaningful potency. We wanted to create a ginger extract that actually worked.

Supercritical CO2 extraction operates at low temperatures while achieving superior concentration of bioactives. This method preserves not only the primary gingerols and shogaols but also the supporting terpenes like citral and alpha-farnesene that contribute to ginger's full spectrum of effects. Our Gut Health focused formula delivers consistent 10% standardization, ensuring you receive therapeutic levels of the compounds that make ginger effective for digestive comfort, Cognition, and inflammatory balance.

Benefits

• Supports Digestive Comfort: Ginger blocks the 5-HT3a serotonin receptor, which underlies many gastrointestinal issues and motion-induced discomfort from traveling.
• Supports Cognitive Function: The gingerols and shogaols help balance neuroinflammation levels, promoting cognitive performance and brain health.
• Supports Metabolic Function: Ginger's bioactive compounds promote cellular function and support healthy Metabolism through multiple pathways.
• Helps Regulate Inflammation: Both gingerol and shogaol work to support balanced inflammation and oxidation levels throughout the body.

Our ginger extract retains naturally occurring terpenes like citral and alpha-farnesene that contribute to ginger's characteristic aroma and enhance the overall effects profile. The supercritical CO2 extraction process preserves these volatile compounds that traditional extraction methods lose, delivering a more complete spectrum of ginger's beneficial constituents for comprehensive Pain and Inflammation support.

Quality and Standardization

• Supercritical CO2 Extraction: We use supercritical carbon dioxide extraction to isolate ginger's bioactive compounds without harsh solvents, preserving the delicate volatile terpenes like citral and alpha-farnesene that contribute to the full spectrum effects profile.
• 10% Gingerols & Shogaols Standardization: Our extract is precisely standardized to deliver a minimum 10% combined gingerols and shogaols by HPLC analysis, ensuring consistent potency of these key phenolic compounds responsible for ginger's therapeutic benefits.
• Third-Party Laboratory Verification: Each batch undergoes comprehensive testing by our third-party labs for identity confirmation, potency verification, and purity analysis including heavy metals, microbiological contaminants, and residual solvents.
• Zingiber officinale Root Source: We exclusively source from the root portion of Zingiber officinale, which contains the highest concentration of bioactive gingerols compared to other plant parts, ensuring maximum therapeutic value per 500mg capsule.

Mechanism of Action

• 5-HT3a Receptor Antagonism: Gingerols and shogaols specifically block the 5-HT3a serotonin receptor in the gastrointestinal tract, which is responsible for nausea signaling and digestive discomfort.
• Prostaglandin Modulation: The bioactive compounds help modulate prostaglandin synthesis pathways, supporting balanced inflammatory responses throughout the body while promoting cellular health.
• Gastric Motility Enhancement: Ginger stimulates gastric emptying and intestinal peristalsis through prokinetic effects, helping food move efficiently through the digestive system.
• Neuroinflammatory Pathway Inhibition: Shogaols cross the blood-brain barrier to inhibit microglial activation and reduce pro-inflammatory cytokines in brain tissue, supporting cognitive function and neurotransmitter balance.

Overview of the Science

Ginger's therapeutic effects stem from its unique bioactive profile, particularly the gingerols and their thermally-converted derivatives, shogaols. Research demonstrates that ginger extract supports digestive comfort through multiple mechanisms, including antagonism of 5-HT3 receptors and modulation of gastric motility [1][2]. Studies indicate that these compounds may also enhance cognitive function in healthy adults through anti-neuroinflammatory pathways, with one clinical trial showing improved working memory and attention in middle-aged women following ginger supplementation [3]. The bioactive compounds further support balanced inflammatory responses by inhibiting pro-inflammatory cytokine production and modulating key inflammatory mediators [4][8].

Clinical research reveals that ginger's metabolic support extends beyond digestive health to include effects on cellular function and oxidative balance. Studies suggest that regular ginger supplementation may help maintain healthy blood sugar levels already within normal range and support lipid profiles in healthy individuals [6]. The compound 6-gingerol specifically demonstrates significant biological activity across multiple cellular pathways, contributing to ginger's broad spectrum of health-promoting effects [7]. These findings support ginger's traditional use as both a culinary spice and therapeutic agent, particularly when concentrated through standardized extraction methods that preserve the full complement of bioactive compounds essential for optimal physiological support [5].

[1] Haniadka R, Saldanha E, Sunita V, Palatty PL, Fayad R, Baliga MS. A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe). Food Funct. 2013;4(6):845-55.

[2] Nikkhah Bodagh M, Maleki I, Hekmatdoost A. Ginger in gastrointestinal disorders: A systematic review of clinical trials. Food Sci Nutr. 2019;7(1):96-108.

[3] Saenghong N, Wattanathorn J, Muchimapura S, Tongun T, Piyavhatkul N, Banchonglikitkul C, Kaewrueng W. Zingiber officinale improves cognitive function of the middle-aged healthy women. Evid Based Complement Alternat Med. 2012;2012:383062.

[4] Lee JS, Kim IS, Kim JH, Kim JS, Kim DH, Yun CY. Suppressive effects of Zingiber officinale Roscoe on proinflammatory cytokines in lipopolysaccharide-stimulated RAW 264.7 cells and acute inflammation animal model. Mediators Inflamm. 2008;2008:469825.

[5] Shirani K, Hassani FV, Razavi-Azarkhiavi K, Hosseinzadeh H. Phytotherapy of cyclophosphamide-induced immunosuppression and leucopenia with Zingiber officinale in mice. Phytother Res. 2015;29(7):1026-31.

[6] Arablou T, Aryaeian N, Valizadeh M, Sharifi F, Hosseini A, Djalali M. The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus. Int J Food Sci Nutr. 2014;65(4):515-20.

[7] Wang S, Zhang C, Yang G, Yang Y. Biological properties of 6-gingerol: a comprehensive review. Arch Pharm Res. 2014;37(4):421-8.

[8] Jalali M, Mahmoodi M, Moosavian SP, Jalali R, Ferns G, Mosallanezhad A, Sohrabi A, Esmaillzadeh A. The effects of ginger supplementation on markers of inflammatory and oxidative stress: a systematic review and meta-analysis of clinical trials. Phytother Res. 2020;34(7):1723-1733.

Ingredients

Ginger Supercritical CO2 Extract:

• Zingiber officinale root extract
• Minimum 10% gingerols and shogaols by HPLC
• 500mg per serving

This minimum 10% standardization ensures consistent delivery of ginger's primary bioactive compounds at therapeutic levels. Unlike standard ginger powders that vary widely in potency, our supercritical extraction process concentrates these volatile compounds while maintaining their natural ratio. The HPLC verification confirms both gingerol content and the thermally-converted shogaols, which form during processing and contribute distinct anti oxidative stress supplements properties beyond fresh gingerols alone. This standardized approach guarantees that each capsule delivers the research-backed compound levels needed for meaningful digestive enzyme supplements support and metabolic benefits.