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Palmitoylethanolamide, or PEA, is a substance that is produced naturally within the body but was also isolated from egg yolk, soy lecithin, and peanut meal in 1954. Endogenously, this fatty acid amide binds to a receptor in the cell nucleus known as the peroxisome proliferator-activated receptor. It plays an important biological role within cells in response to pain. Palmitoylethanolamide appears to be produced in the body on-demand in areas of pain.
Research over the past several decades is leading to a greater understanding of the compound and its efficacy in improving conditions marked by pain.
Although it is produced in our bodies, supplementation with naturally derived Palmitoylethanolamide may further help the body in response to pain. Research and clinical use in Italy, Spain, the Netherlands, and Germany suggests that Palmitoylethanolamide may support a variety of pain states.
As more research is conducted this compound could prove to be useful in supporting pain management.
As a dietary supplement, take one 400mg Palmitoylethanolamide capsule daily.
Get more insight by reading Palmitoylethanolamide reviews below.
Product includes one (1) 60ct. or 180ct. jar of Palmitoylethanolamide (PEA) Capsules.
*Attention: This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.
I haven't had anything this effective for pain that didn't make me feel drugged. I scarcely notice it aside from the pain relief. I've only been using it a week, so I'm a strong responder. Here's a study you can look at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631430/ Katherine Wolfe on 26th Sep 2018
Great product for chronic pain if you want to get off opioids, ibuprofen,aleive, etc. My wife and I both did a loading phase then reduced the amount until we hit the ideal dosage for us. Did not work immediately but after it built up in my body it did what I needed. Have bought this product several times and will continue and my wife also swear Jess on 28th Dec 2017
Very similar to pea-pure but cheepest Fran Ruiz on 18th Nov 2017
No pain relief or any difference at all. Could be too soon to tell as have been taking less than a month. Going to keep going and pray it helps. shannon on 26th Aug 2017
It may take up to 8 weeks for the full Pain relieving effects of Palmitoylethanolamide to be noted. It's nice to know I found a good, reliable, fairly price place to purchase in Nootropicsdepote.com. I will continue to order from them in the future. Denise Bogan on 1st Nov 2016
Due to sharing many common receptor chains/pathways with CBD, I've found this to be a pretty good adjunct to CBD therapy. It makes me need less, as long as I stick to my 600mg x 3/day (I cap them myself, at this higher dose, since I purchased it in powder form and it fit comfortably into a size 00 capsule when tampered effectively in a capsule machine). I wish it had a little more "oomph" to it, but I suppose thats the trade-off when side effects are minimal (only thing ever experienced was a tolerable feeling of heaviness in my stomach, and not always). 8/10 would recommend. srubek on 30th Oct 2016
my doctor suggested I try PEA. After over a month all I can say is that it's really working. please speak your doctor about adding PEA to your regimen. Valerie Williams on 29th Oct 2016