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Pomella is a pomegranate extract that has undergone human clinical research. Exhibiting potent antioxidant activity, it has been shown to help regulate inflammatory processes, along with promoting healthy vascular and cellular function. Pomella is standardized to punicalagins, ellagitannins which are known to hydrolyse, or break down, into ellagic acid, and are therefore the major players behind the fruit's radical-scavenging power. By preserving the native ratio of whole pomegranate polyphenols, including punicalagins, Pomella provides the antioxidant potency of several pomegranates in one small, clinically researched dose. More than 30 clinical trials show punicalagins, the bioavailable and bioactive component from pomegranate fruit as found in Pomella, significantly benefit blood pressure, LDL cholesterol oxidation, and other markers of cardiovascular health. Recent studies also show that punicalagins from pomegranate support a number of health applications related to inflammation and oxidative stress. Pomella has been shown to increase plasma levels of urolithin A, urolithin B, hydroxyl-urolithin A, urolithin A-glucuronide, and dimethyl ellagic acid-glucuronide. Those compounds have been shown to have potent antioxidant and anti-aging effects.
A 2014 UCLA study showed Pomella® ranked highest in antioxidant activity across a number of assays includingORAC, TEAC, FRAP and DPPH, compared to 26 other antioxidant products (1). In other 2014 studies, Pomella® was shown to impact cognitive function and markers of healthy brain aging, and inhibit AGE - advanced glycation end products (2,3).
A study by researchers at the University of Florida found that a single dose of Pomella led to a significant, 32% increase of antioxidant activity in one hour after dosing (4).
A study by researchers at Texas A&M University found that Pomella® absorbs into colon cells as bioactive metabolites. In contrast, purified ellagic acid did not absorb. This study suggested that the main pomegranate polyphenol needed for bioactivity is punicalagins, not ellagic acid (5).
Product contains one (1) 15g or 30g jar of Pomella Extract Powder.
1. Liu et al. Food and Function 2014. DOI: 10.1039/c4fo00538d
2. Ahmed et al. Current Alzheimer’s Research 2014 (11).
3. Henning et al. J. Agric. Food Chem. 2014, 62, 4313−4321
4. Mertens-Talcott et al. J Agric Food Chem. 2006 Nov
5. Cell transport of Pomella in CACO-2 cell line, Texas A&M,
I have been using this as adjunct to supplement regime and it has slotted in just perfectly.
I take it first thing in the morning on an empty stomach with my probiotics.
It increases my energy levels and mental clarity. It is also a useful pump inducer for the gym.
Would HIGHLY recommend testing out this nutritionally dense powerhouse. Lucas Aoun on 23rd Jul 2016
I've had issues with frequent urination and the inability to hold it when I'm working or driving. I've done some great kidney cleanses that helped pass some stones. I have used different herbs that help the kidneys like horsetail and chanca piedra. I used a great prostate tincture a couple times, but it didn't have pomegranate in it. Nettle Root had a noticeable effect on my frequent urination, but it didn't seem to be permanent. It only worked when I took it.
This pomegranate extract has worked wonders for me, however. I took the first container pretty consistently everyday. Things were getting much more manageable, less feelings of urgency to go pee. Now I take it maybe once every week or two and it has really helped with everything.
Thanks for making this product available! You can't really find a good pomegranate supplement out there for a good price. This is the best pomegranate offering on the web. Thanks, ND. Phil on 7th Jun 2016
I've been taking pomella @ 150mg once to twice daily, for about 3 weeks or so. I notice a nice sense of mental clarity about 30 minutes after ingestion, as well as decreased inflammation, better looking skin, and perhaps digestive benefits as well. It's a great supplement. Unknown on 2nd May 2016
It's been a few days since i've been taking pomella, and if there's an effect that i've noticed, it would be sense of ease and mental clarity. Placebo perhaps, but even so, the studies i've read supporting pomegranate benefits are convincing enough to encourage me to make it a staple, (especially prostate health, intestinal flora support, brain health). First time ordering with nootropicsdepot and everything went perfectly. Rob on 16th Feb 2016