Nootropics Depot Free Shipping on USA orders over $50
Same-Day Shipping on Most Orders Placed Mon. - Sat. by 4pm AZ MST
Business Hours: Mon. - Sat. 9am - 5pm AZ MST
Image 1

PRL-8-53 Powder

  • Product Description

    What is PRL 8 53?

    PRL-8-53 is a hypermnesiac nootropic developed by Nikolaus Hansel at Creignton University. A double-blind trial of 47 healthy human volunteers led to a word retention rate of 205% over the course of one week dosing at 5mg, 2-2.5 hours before studying. Subjects over 30 years old showed even more improvement with results at 252% of baseline performance. The exact mechanism for PRL-8-53 is unknown. However, it does not display stimulant properties and does not potentiate stimulants like dextroamphetamine.

    PRL 8 53 Reviews

    To learn more, see the PRL-8-53 reviews and experiences that are available below. There are over 25 anecdotal PRL-8-53 reviews and experiences available that may be helpful to you in your research. 

    Where to Buy PRL-8-53?

    Nootropics Depot offers half gram, 1 gram or 5 gram jars of PRL-8-53 powder. Nootropics Depot's PRL-8-53 powder has been lab-tested and verified for both product purity and identity.

    Attention: All chemical compounds have risks. Please consult your physician, and understand the available research, before consumption. This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.

  • Product Reviews


    Write A Review


      Took a risk and took 5g for my first purchase of this stuff! crazy af.
      Anyway my experience with this is very good, my short term memory really fucked up
      this compund is a godsend for me, I barely noticed any effect besides the boost of short term memory.
      I am cycling this to 2 times a week max, and I feel it effects me positively in the long term..
      on 5th Jan 2018


      This is my third day using it at 5mg subligually, short-term memory is better for sure.
      No side effects so far.. no mood boost either,
      on 30th Dec 2017

    3. Verbal Acuity

      I have great success with PRL, especially as it’s not unfamiliar for me to have feelings of social anxiety. I work in customer service and it helps me communicate easier and more effectively. I also like to take it before a night out with friends because it helps coversation flow. I find myself much more open in regards to topics that I’m comfortable talking about, too. I highly recommend. on 15th Dec 2017

    4. mastering music

      Not only have i found that with this can i read like never before and comprehend much better than i ever have, but i have also found that i am much better at music wroting and playing with this. It has improved my musical ear by multitudes and gives a nice calm focused euphoria. on 21st Nov 2017

    5. This is powerful

      This seems to only improve memory and does not provide any kind of concentration enhancement, so far. I think 10mg is about right for me. For what it does, this stuff is as good as or better than phenylpiracetam, which is the strongest safe nootropic I have used. All the nasty orajel type comments +1. on 17th Oct 2017

    6. I'm a big fan

      I originally bought PRL 8-53 on a whim to supplement my stack of phenlypiracetam and noopept. At first I didn't take it too often and never by itself. I only really started to use it when I ran out of phenylpiracetam. After a few days I realized that my attention and especially my recall were on a level I hadn't experienced in quite a while. I was right in the middle of a web coding bootcamp at the time and believe me, there was a lot of new info swimming around in my brain. Even small details came to me easily. It made a believer out of me. Tastes like hell but I still take it every day. on 7th Aug 2017

    7. Works as I expected it to

      My short term memory has been improved radically and I now can remember having vivid dreams after I wake up in the morning (something that hasn't been possible for me before). Even though this substance has not been researched well, I think from my experience of testing it out on myself as a guinea pig, that it works pretty well on 26th Jul 2017

    8. something but nothing special

      I was pretty pumped when I read the study on it. I can tell you now i wasn't super impressed. Also it numbs your mouth big time.... Like putting orajel in your mouth but nasty and lingering. on 21st Jul 2017

    9. auphoria

      All I got from this was a auphoric feeling for two hours, as far as memory is concern uhm no not really, would I try it again yes I woukd give it a second shot. on 3rd Jun 2017

    10. Probably lives up to the hype

      On its own: definitely provides memory boost with a side benefit of a mood boost
      In stack: I stacked 25-40mg of prl with 30-50mg of noopept a number of times, and noticed significantly improved memory retention, mood boost, and overall cognitive boost undoubtedly greater than that of just noopept.
      on 31st May 2017

  • Find Similar Products by Category