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Fenugreek Research Snapshot

Research Snapshot

Fenugreek

A synthesis of the peer-reviewed evidence for Fenugreek across libido, metabolism, hormones and inflammation, graded by scientific consensus and reviewed by our Scientific Advisory Board.

61 studies analyzed 4 benefit areas Reviewed by the SAB Updated Jul 2026

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Libido

Can Fenugreek enhance libido?

Evidence from 12 studies

Yes
75%
9 studies
Possibly
17%
2 studies
No
8%
1 study

What the research shows

Current clinical evidence supports that standardized fenugreek extracts can enhance libido in both men and women, likely by increasing free testosterone and improving related physiological and psychological factors. These effects are seen with daily supplementation and are generally considered safe in healthy adults.

View the top studies
Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum‐graecum Extract and Mineral Formulation

Phytotherapy Research | E. Steels et al. | 70 | 2011

Randomized Control Trial (RCT) , Highly Cited

Testofen, a standardized Trigonella foenumñ graecum (Fenugreek) extract and mineral formulation, significantly increases sexual arousal and orgasm.

Efficacy of FurosapTM, a novel Trigonella foenum-graecum seed extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Volunteers

International Journal of Medical Sciences | A. Maheshwari et al. | ·40 | 2017

Non-Randomized Control Trial , Rigorous Journal

Furosap, a 20% protodioscin-enriched extract from fenugreek seeds, significantly improves libido, mental alertness, cardiovascular health, and overall performance in human subjects.

A novel protodioscin-enriched fenugreek seed extract (Trigonella foenum-graecum, family Fabaceae) improves free testosterone level and sperm profile in healthy volunteers

Functional Foods in Health and Disease | D. Bagchi et al. | 4 | 2017

Non-Randomized Control Trial

Furosap, a standardized fenugreek seed extract, significantly improves libido performance in male volunteers.

Safety and Efficacy of Furosap, a novel Trigonella foenum‐graecum seed extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Human Volunteers

The FASEB Journal | M. Bagchi et al. | 1 | 2017

Non-Randomized Control Trial

Furosap, a 20% protodioscin-enriched extract from fenugreek seeds, effectively increased testosterone levels and significantly improved libido in male volunteers.

Metabolism

Can Fenugreek support metabolic function?

Evidence from 16 studies

Yes
81%
13 studies
Possibly
19%
3 studies
No
0%
0 studies

What the research shows

Fenugreek supports metabolic function through multiple pathways, including improving blood sugar and lipid levels, reducing inflammation, and positively influencing the gut microbiome. These effects make it a promising supplement for supporting healthy metabolic function.

View the top studies
Fenugreek Counters the Effects of High Fat Diet on Gut Microbiota in Mice: Links to Metabolic Benefit

Scientific Reports | A. Bruce-Keller et al. | 27 | 2020

Rigorous Journal

Fenugreek counteracts the adverse effects of high fat diets on gut microbiota, stabilizes glucose tolerance, and reverses dysbiotic effects, correlated with overall metabolic function.

Cross-Omics Analysis of Fenugreek Supplementation Reveals Beneficial Effects Are Caused by Gut Microbiome Changes Not Mammalian Host Physiology

International Journal of Molecular Sciences | Katarina A. Jones et al. | 4 | 2022

Non-Randomized Control Trial , Animal Trial

Fenugreek supplementation leads to significant alterations in the gut microbiome and impacts multiple metabolic pathways, including carnitine biosynthesis, cholesterol and bile acid metabolism, and arginine biosynthesis.

Effects of Fenugreek Supplementation on the Components of Metabolic Syndrome: A Systematic Review and Dose-Response Meta-analysis of Randomized Clinical Trials.

Pharmacological research | Laleh Fakhr et al. | 9 | 2022

Rigorous Journal , Meta Analysis

Fenugreek supplementation can meaningfully reduce fasting plasma glucose, triglyceride, waist circumference, and systolic blood pressure and increase HDL.

Flavonoid Glycosides from Fenugreek Seeds Regulate Glycolipid Metabolism by Improving Mitochondrial Function in 3T3-L1 Adipocytes in Vitro.

Journal of agricultural and food chemistry | Guangxiang Luan et al. | 47 | 2018

In Vitro Trial

Isoorientin, a flavonoid glycoside from fenugreek seeds, improves mitochondrial function and regulates glycolipid metabolism.

Hormones

Can Fenugreek improve hormonal balance?

Evidence from 14 studies

Yes
71%
10 studies
Possibly
14%
2 studies
No
14%
2 studies

What the research shows

Fenugreek supplementation has demonstrated the ability to improve hormonal balance in women, especially around menopause and in women's health research, by increasing beneficial hormones and supporting overall wellness. It is generally safe when used as studied, making it a promising natural option for hormonal health support.

View the top studies
A Novel Extract of Fenugreek Husk (FenuSMART™) Alleviates Postmenopausal Symptoms and Helps to Establish the Hormonal Balance: A Randomized, Double‐Blind, Placebo‐Controlled Study

Phytotherapy Research | S. Begum et al. | 46 | 2016

Randomized Control Trial (RCT) , Highly Cited

Fenugreek extract supplementation at 1000 mg/day significantly increased plasma estradiol and improved postmenopausal discomforts and quality of life.

Efficacy of a novel extract of fenugreek seeds in alleviating vasomotor symptoms and depression in perimenopausal women: A randomized, double-blinded, placebo-controlled study.

Journal of food biochemistry | A. Khanna et al. | 18 | 2020

Randomized Control Trial (RCT)

Fenugreek extract supplementation at 250 mg μ 2/day for 42 days significantly reduced vasomotor symptoms and depression in perimenopausal women, achieving a hormonal balance without any adverse effects.

Phytoestrogenic effect of fenugreek seed extract helps in ameliorating the leg pain and vasomotor symptoms in postmenopausal women: A randomized, double-blinded, placebo-controlled study

PharmaNutrition | Jestin V Thomas et al. | 12 | 2020

Randomized Control Trial (RCT)

Fenugreek seed extract supplementation at 250 mg μ 2/day for 42 days significantly reduced hot flashes, night sweats, leg pain, and irritability in postmenopausal women.

Diosgenin and Its Fenugreek Based Biological Matrix Affect Insulin Resistance and Anabolic Hormones in a Rat Based Insulin Resistance Model

BioMed Research International | Rita Kiss et al. | 25 | 2019

Non-Randomized Control Trial , Animal Trial , Rigorous Journal

Fenugreek seeds improved peripheral insulin sensitivity and reduced thyroid hormone levels.

Inflammation

Can Fenugreek balance inflammation levels?

Evidence from 19 studies

Yes
95%
18 studies
Possibly
5%
1 study
No
0%
0 studies

What the research shows

Overall, fenugreek demonstrates significant potential to balance and reduce inflammation, especially in metabolic and inflammatory conditions. While animal and cellular studies show strong effects, human evidence is promising but more limited. Fenugreek may be a useful natural option for supporting healthy inflammation levels.

View the top studies
Does fenugreek (Trigonella foenum-graecum) seed improve inflammation, and oxidative stress in patients with type 2 diabetes mellitus? A parallel group randomized clinical trial

European Journal of Integrative Medicine | Rahele Tavakoly et al. | 44 | 2018

Randomized Control Trial (RCT)

Fenugreek seed consumption resulted in a significant decrease in high-sensitivity C-reactive protein and increased superoxide dismutase activity in type 2 diabetes mellitus patients.

Role of nitric oxide (NO) in the modulation of anti‐arthritic and anti‐inflammatory effects of Trigonella foenum‐graecum (fenugreek) ethanolic seed extract in rats

The FASEB Journal | Rishi Pal et al. | 0 | 2020

Non-Randomized Control Trial , Animal Trial , Rigorous Journal

Ethanolic fenugreek seed extract (FSE) shows significant protective role in arthritic and inflammatory parameters, and oxidative stress markers, in a dose-dependent manner.

Fenugreek attenuates obesity-induced inflammation and improves insulin resistance through downregulation of iRhom2/TACE.

Life sciences | Cong Zhou et al. | 16 | 2020

Non-Randomized Control Trial , Animal Trial

Fenugreek suppresses inflammation and insulin resistance in obesity by downregulating iRhom2/TACE expression.

Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues.

Molecular nutrition & food research | Taku Uemura et al. | 148 | 2010

Non-Randomized Control Trial , Animal Trial , Highly Cited

Fenugreek ameliorated diabetes by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues.

Reviewed by Experts

Reviewed by the Scientific Advisory Board

Every research snapshot is checked by our independent Scientific Advisory Board: physicians, botanists and pharmacology researchers who verify the evidence grading and its interpretation.

Kerry Hughes

M.Sc., RH(AHG), FDN-P

Ethnobotanist & herbalist; Berkeley Herbal Center; principal at EthnoPharm.

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Lance Dreher

PhD, Nutritional Counseling

Performance nutrition & conditioning; four decades of applied training science.

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Dr. Lindsey Faucette

DO, FAAFP

Board-certified in Family & Integrative Medicine; Touro University College of Osteopathic Medicine.

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Francisco Chacon

PhD, Plant Biology

Botanical natural products & phytochemistry researcher, Penn State University.

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How We Grade Consensus

For each benefit we retrieve the relevant peer-reviewed literature and classify every study by whether its findings support (Yes), partially or conditionally support (Possibly), or do not support (No) the claim. The donut shows the share of studies in each category; N is the number of studies analyzed for that benefit.

Grades reflect the weight and direction of the current evidence, not a guarantee of outcome, and the interpretation is verified by the Scientific Advisory Board.

Data sourced from published, peer-reviewed research. Citations link to the original studies. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Last reviewed Jul 2026 · Meet the Scientific Advisory Board.