About Infini-B Capsules
Infini-B is a comprehensive B-complex featuring premium forms of all eight essential B vitamins, including the neurotropic benfotiamine and methylcobalamin. This formula supports energy production from food, neurotransmitter synthesis, and metabolism, addressing the body's constant need to replenish these water-soluble vitamins that cannot be stored long-term.
Our Infini-B Story
As supplement users ourselves, we constantly searched for a B-complex without compromises, but kept finding products with inferior forms, improper dosing, or both. Most manufacturers use poorly absorbed forms like cyanocobalamin or folic acid, while others sprinkle a few premium forms into formulas dominated by cheap alternatives. We wanted to create something different: a B-complex using only the most bioavailable and active forms of each vitamin.
We approached this methodically, selecting forms like P5P for B6, L-5-MTHF for folate, and dual forms of B12 for optimal utilization. Then came the challenge of proper dosing. B vitamins are notoriously over or under-dosed in most products, so we conducted extensive beta-testing to find the sweet spot where each vitamin delivers meaningful benefits without excess. The result is a formula that provides noticeable energy and cognitive support while maintaining perfect balance across all eight B vitamins.
Benefits
- Promotes Energy: Infini-B supports efficient conversion of carbohydrates, fats, and proteins into usable energy through optimized forms like P5P and riboflavin 5'-phosphate that enhance cellular ATP production.
- Supports Cognitive Function: The formula includes benfotiamine for enhanced blood-brain barrier penetration and L-5-MTHF-Ca to support neurotransmitter supplements synthesis including dopamine, serotonin, and acetylcholine supplements.
- Mood Support: Contains methylcobalamin and hydroxycobalamin to support healthy methylation processes essential for neurotransmitter balance and emotional well-being.
- Metabolic Support: Features D-calcium pantothenate for coenzyme A production and no-flush niacin forms that support healthy cholesterol levels and cardiovascular function.
Infini-B's formula addresses the interconnected nature of cellular processes, where proper methylation supports both mental clarity and physical vitality while maintaining healthy homocysteine levels already within the normal range.
Quality and Standardization
- Premium Active Forms: We use only the most bioavailable forms of each B vitamin, including benfotiamine for enhanced brain penetration, P5P as the active B6, and L-5-MTHF calcium as the methylated folate that bypasses genetic conversion issues.
- Dual B12 Complex: Features both methylcobalamin and hydroxocobalamin to provide comprehensive B12 support, as these two forms work synergistically to optimize methylation pathways and neurotransmitter supplements production.
- No-Flush Niacin Blend: Contains both niacinamide and inositol hexanicotinate for sustained NAD supplements precursor delivery without uncomfortable flushing reactions, while maintaining full vitamin B3 activity.
- Optimized Biotin Dosing: Carefully dosed at physiological levels to support metabolism without the skin disruption that can occur with mega-dose biotin formulations found in many complexes.
- Beta-Tested Formula: Underwent extensive internal testing to verify optimal dosing ratios across all eight B vitamins, ensuring balanced effects without the energy crashes or overstimulation common with poorly formulated B-complexes.
Mechanism of Action
- Enzymatic Cofactor Activation: B vitamins convert into their active coenzyme forms to power cellular energy production, with thiamine becoming thiamine diphosphate for glucose metabolism, riboflavin transforming into FAD and FMN for electron transport, and pantothenic acid generating coenzyme A for fatty acid oxidation and the citric acid cycle.
- Neurotransmitter Pathway Support: Multiple B vitamins work synergistically in neurotransmitter synthesis, with P5P catalyzing dopamine and serotonin production, methylcobalamin and folate supporting methionine recycling for SAMe-dependent reactions, and benfotiamine crossing the blood-brain barrier to enhance acetylcholine formation.
- Methylation Cycle Optimization: L-5-MTHF calcium and methylcobalamin directly participate in one-carbon metabolism, bypassing genetic polymorphisms that impair folate conversion while supporting DNA methylation, homocysteine metabolism, and SAMe regeneration for optimal cellular function.
- Mitochondrial Electron Transport Enhancement: Riboflavin 5'-phosphate serves as a precursor to flavoproteins that facilitate electron transfer in Complex I and II of the mitochondrial respiratory chain, while niacinamide supports NAD+ synthesis essential for oxidative phosphorylation and cellular energy currency production.
Overview of the Science
B vitamins function as essential cofactors in enzymatic reactions that regulate cellular energy metabolism and neurotransmitter synthesis [1]. Research indicates that B vitamin deficiencies can significantly impair cognitive performance, with studies showing that supplementation with bioavailable forms like those in Infini-B supports memory formation, mental clarity, and overall brain function [2][3]. Vitamin B12 specifically enhances nerve repair and improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuron injury [4]. Additionally, B vitamins play crucial roles in myelin maintenance and repair, which is essential for proper nerve signal transmission and cognitive health [5].
Clinical trials demonstrate that B complex supplementation can reduce fatigue and improve exercise performance in healthy individuals, supporting the energy-promoting effects users experience with Infini-B [6]. The neuropsychiatric benefits of B vitamins are well-documented, with deficiencies linked to mood disturbances, cognitive decline, and memory impairment [7][8][9]. Studies specifically highlight the role of B vitamins in preventing and treating cognitive decline, particularly in areas of executive function and processing speed [10].
[1] Stremmel C, Hanning U, Möhring A, et al. B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin. Biomed Res Int. 2019;2019:9968228.
[2] Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review. Nutrients. 2016;8(2):68.
[3] Baltrusch S. The Role of Neurotropic B Vitamins in Nerve Regeneration. BioMed Res Int. 2021;2021:9968228.
[4] Wu M, Ding H, Tang X, et al. Vitamin B12 Enhances Nerve Repair and Improves Functional Recovery After Traumatic Brain Injury by Inhibiting ER Stress-Induced Neuron Injury. Front Neurosci. 2019;13:406.
[5] Miller A, Korem M, Almog R, Galboiz Y. Vitamin B12, demyelination, remyelination and repair in multiple sclerosis. J Neurol Sci. 2005;233(1-2):93-7.
[6] Patel A, Hou W, Sajjan S. A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans, a randomized double-blind trial. Int J Med Sci. 2023;20(10):1275-1289.
[7] Han A, Almeida L, Anand N, et al. Exploring neuropsychiatric manifestations of vitamin B complex deficiencies. Front Psychiatry. 2025;16:1569826.
[8] Ankar A, Kumar A. Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia. Cureus. 2020;12(2):e6976.
[9] Boccazzi A, Argento O, Petrucci L, et al. Vitamin B12 deficiency and cognitive impairment: Is there a distinctive cognitive domain affected? Alzheimer Dement. 2023;19:e073432.
[10] Morris MS. The Role of B Vitamins in Preventing and Treating Cognitive Impairment and Decline. Adv Nutr. 2012;3(6):801-812.
Ingredients
- Essential for glucose metabolism, nervous system function, and mitochondrial energy production
- Ingredient source: 57 mg Thiamine HCl and 50 mg Benfotiamine
- Amount per serving: 50 mg thiamine
- Primary benefit: Combines standard and lipid-soluble forms to support both peripheral and central nervous system thiamine status
- Key cofactor for FAD and FMN, which drive mitochondrial ATP production
- Ingredient source: 35 mg Riboflavin 5'-phosphate sodium
- Amount per serving: 25 mg riboflavin
- Primary benefit: Provides an active coenzyme form that is readily utilized in energy pathways
- Supports NAD and NADP production for cellular energy, redox balance, and DNA repair
- Ingredient source: 100 mg Niacinamide and 181 mg Inositol hexanicotinate
- Amount per serving: 264 mg niacin equivalents (NE)
- Primary benefit: Combines immediate and sustained niacin forms to support NAD production with minimal flushing
- Forms coenzyme A, essential for fatty acid oxidation, acetylcholine synthesis, and adrenal hormone production
- Ingredient source: 110 mg D-calcium pantothenate
- Amount per serving: 100 mg pantothenic acid
- Primary benefit: Supports metabolic flexibility, stress resilience, and neurotransmitter synthesis
- Regulates amino acid metabolism and neurotransmitter synthesis, including serotonin, GABA, and dopamine
- Ingredient source: 25 mg Pyridoxal 5'-phosphate
- Amount per serving: 25 mg vitamin B6
- Primary benefit: Active coenzyme form is immediately available for enzymatic reactions
- Cofactor for carboxylase enzymes involved in gluconeogenesis, fatty acid synthesis, and amino acid metabolism
- Ingredient source: D-Biotin
- Amount per serving: 30 mcg
- Primary benefit: Supports metabolic health and contributes to healthy hair, skin, and nails
- Supports methylation, DNA synthesis, and healthy homocysteine metabolism
- Ingredient source: 500 mcg L‑5‑MTHF calcium
- Amount per serving: 680 mcg dietary folate equivalents (DFE)
- Primary benefit: Methylated folate form bypasses common MTHFR polymorphisms for reliable utilization
- Supports myelin integrity, red blood cell formation, and methylation cycles
- Ingredient source: 250 mcg methylcobalamin and 250 mcg hydroxocobalamin
- Amount per serving: 500 mcg vitamin B12
- Primary benefit: Dual cobalamin forms provide both rapidly available B12 and longer-lasting tissue stores