Polygala tenuifolia 20:1 Extract Capsules (Yuan Zhi)
Polygala tenuifolia, commonly referred to as Yuan Zhi, Chinese senega and thinleaf milkwort, is a root that is commonly used in traditional Chinese medicine, where it is known as yuan zhi. In its traditional use, Polygala tenuifolia reportedly had protective effects on the brain. Current studies suggest that Polygala tenuifolia may act as a powerful nootropic.
How Do Polygala tenuifolia 20:1 Extract Capsules Work?
Research on rodent subjects suggest that Polygala tenuifolia’s main mechanism of action and effect involve interactions with NMDA (N-methyl-D-aspartic acid) and NMDA receptors. NMDA is an amino acid derivative that is similar in function to glutamate. While small amounts of NMDA may be normal or may even prove beneficial, it is generally categorized as an excitotoxin, meaning it can cause over-excitation of nerve cells by flooding receptors, potentially resulting in cell damage and death.
NMDA may also increase the release of glutamate, an amino acid and neurotransmitter that is involved in nearly all forms of normal brain functions. Glutamate acts as mediator of excitatory signals in the brain, but a flood of glutamate or a sensitivity to the neurotransmitter can cause cells to become overexcited, leading to glutamate-induced excitotoxicity.
Polygala tenuifolia Uses and Benefits
Sometimes referred to as Thinleaf Milkwort, Yuan Zhi, or Chinese Senega, Polygala tenuifolia is a root used in traditional Chinese medicine. Early animal research suggests that it may have mood boosting properties and promote brain health. Additional animal research has suggested that Polygala tenuifolia may also have adaptogen-like properties and therefore increases nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). Additionally, it may improve spatial organization/recognition and increase cognitive ability.
Polygala tenuifolia Dosage
As a dietary supplement, take one 100mg Polygala tenuifolia 20:1 Extract capsule three times daily.
This extract is a 20:1 Dual Water/Ethanol Extract.
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Product contains one (1) 90ct. or 180ct. jar of Polygala tenuifolia 20:1 Extract 100mg capsules (Yuan Zhi).
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*Attention: This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.