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Poria Mushroom Extract Powder

Standardized to 55% beta-glucans for immune, digestive, respiratory, and cognitive health support.

(2 Reviews) Write a Review

View All Reviews

Poria Mushroom Extract Powder

Standardized to 55% beta-glucans for immune, digestive, respiratory, and cognitive health support.

(2 Reviews) Write a Review

View All Reviews

Available in multiple forms! Click Here for:
  • Pure Fruiting Body Extract
  • Standardized to 55% Beta-Glucans
  • Rich in Bioactive Pachymic Acid
  • Traditional Cognitive Support

3rd Party Lab Tested & Verified

See Why ND Poria Is The Best

Updated On: 05/23/2026

$14.99

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ATTENTION: This product does not include a scoop. Learn more

Benefits

When You'll Notice Effects

2-3 Weeks

  • Immune
  • Inflammation
  • Neuroprotection
  • Oxidation

Why ND Poria Mushroom?

55% Beta-Glucan Content, The Highest Standardized Poria Extract We Tested
test

How To Take

Dose
Dose

500mg (Per Serving)

Timing
Timing

Flexible

How to Take
How to Take

With Or Without Food

Frequency
Frequency

1-2 Times Daily

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  • About Poria Mushroom Extract Powder

    Wolfiporia extensa extract is a whole fruiting body mushroom supplement standardized to 55% beta-glucans for consistent potency. This wood-decay fungus produces distinctive coconut-like sclerotia containing triterpenoid compounds and monosaccharides that support cellular function, immune health, and cognitive wellness. Research highlights the bioactive compound pachymic acid for its supportive cellular effects.

    Our Poria Story

    Most Poria cocos extracts came from the inner white portion of the sclerotium rather than the whole fruiting body, limiting their bioactive compound diversity. Many products also lacked standardization, creating inconsistent potency across batches. Traditional Chinese practices relied on whole Poria preparations, yet supplement manufacturers focused only on isolated sclerotium portions.

    We sourced certified organic whole fruiting body extract to capture the complete spectrum of triterpene derivatives, beta-glucans, and unique amino acids found throughout the entire mushroom structure. Standardization to 55% beta-glucans ensures reliable dosing of these crucial immune-supporting polysaccharides. This approach delivers the traditional benefits that made Poria a cornerstone of classical formulations, particularly when paired with Polygala tenuifolia for cognitive support.

    Benefits

    • Supports Healthy Immune Function: Rich in beta-glucans and triterpenoids, Poria mushroom supports your body's natural defense mechanisms.
    • Supports a Healthy Inflammatory Response: Pachymic acid and other triterpenoid compounds support a balanced inflammatory response throughout the body.
    • Supports Healthy Brain Function: Research shows Poria promotes cerebral blood flow, supporting healthy acetylcholine levels and memory formation processes.
    • Supports Healthy Antioxidant Activity: The unique mix of triterpene derivatives and monosaccharides supports cells against oxidative stress.

    Traditionally paired with Polygala tenuifolia in Chinese practices for cognitive support, Poria extends its benefits beyond the brain to support organ, digestive, and respiratory health, making it a comprehensive wellness mushroom for whole-body support.

    Quality and Standardization

    • Certified Organic Whole Fruiting Body: Our Poria extract is sourced exclusively from certified organic whole fruiting bodies, ensuring maximum bioactive compound density compared to mycelium-based alternatives.
    • 55% Beta-Glucan Standardization: Each batch is standardized to contain a minimum of 55% beta-glucans, verified through advanced analytical testing for consistent immune-supporting potency.
    • Third-Party Laboratory Verification: We conduct comprehensive testing through independent third-party labs to verify product identity, purity, and the absence of contaminants including heavy metals and microorganisms.
    • Traditional Sclerotium Source: Our extract utilizes the prized sclerotium portion of Wolfiporia extensa, the same dense mycelial mass valued in traditional practices for its concentrated triterpenoid content.
    • UPLC-Verified Pachymic Acid Content: Advanced UPLC testing confirms the presence of pachymic acid and other bioactive triterpenoids that support healthy cellular health supplements mechanisms.

    Mechanism of Action

    • Beta-Glucan Immune Modulation: The 55% beta-glucan content activates key immune cells including macrophages, dendritic cells, and natural killer cells through specific receptor binding, supporting your body's ability to recognize and respond to threats while maintaining balanced immune function.
    • Triterpenoid Cellular Support: Pachymic acid and other triterpenoid compounds work at the cellular level to support mitochondrial function and maintain healthy oxidative balance, supporting cells against environmental stressors and supporting efficient energy production.
    • Cerebral Blood Flow Support: Bioactive compounds in Poria promote healthy circulation to the brain, supporting optimal delivery of oxygen and nutrients while facilitating the clearance of metabolic waste products that can impact cognitive function.
    • Acetylcholine System Support: The improved cerebral circulation helps maintain healthy levels of acetylcholine, a crucial neurotransmitter involved in learning, memory consolidation, and overall brain communication pathways essential for memory formation.

    Overview of the Science

    Research demonstrates that Poria mushroom extracts containing pachymic acid and polysaccharides support gut health through multiple mechanisms [1][2][3]. Studies show that water-insoluble polysaccharides from Poria cocos help regulate the gut microbiota in mice models, while also supporting intestinal barrier function and maintaining homeostasis in the digestive tract. Research indicates the pachymic acid component activates the Nrf2/GPX-4 pathway to support healthy cellular function against oxidative stress [4][5].

    Emerging research has also explored Poria's potential for respiratory health support, with studies indicating that Poria cocos oligosaccharides support healthy respiratory function in animal models [6]. The immunomodulatory activity of Poria polysaccharides has been documented through multiple mechanisms, with two distinct polysaccharides from the mushroom demonstrating measurable effects on immune function [7][8]. Additionally, research in Caenorhabditis elegans models suggests that Poria polysaccharides support healthy aging processes through antioxidant mechanisms [9].

    [1] Yang J, Tang J, Chen JJ, Peng AY, Wang QM, Rao LQ, Yang H, Zhang XW, Liu H. J Ethnopharmacol. 2021;282:114650.

    [2] Lai Y, Deng H, Fang Q, Ma L, Lei H, Guo X, Chen Y, Song C. Nutrients. 2023;15(17):3719.

    [3] Guo M, Liu Z, Li J. Food Funct. 2023;14(20):9309-9320.

    [4] Zhang Z, Chen C, Zhou J, Li C, Du X, Hou H, Yang Y. Int J Biol Macromol. 2025;308:143030.

    [5] Zhang C, Xiong Y, Gong M, Zhao H, Li S, Chen X, Zhao L. Phytomedicine. 2024;124:155311.

    [6] Guo Y, Liu L, Li J. Front Nutr. 2026;13:1774161.

    [7] Zhang W, He J, Zheng D, Zhao P, Wang Y, Zhao J. Molecules. 2023;29(1):50.

    [8] Li X, Ma LN, Zhang LJ. J Cell Mol Med. 2019;23(1):4-20.

    [9] Tang YJ, Song ZY, Huang YQ, Wang YT, Deng JZ, Zhen DG, Tan NH. Chin Tradit Herb Drug. 2024;55:1133-44.

    Ingredients

    Wolfiporia extensa Extract (Sclerotium):

    • 500mg per serving
    • Pure extract with no fillers or additives
    • Sourced from the sclerotium (underground fungal mass)

    This pure Poria extract focuses specifically on the sclerotium, the dense underground storage organ where Wolfiporia extensa concentrates its most bioactive compounds. Unlike whole mushroom powders that include less active fruiting body material, this targeted extraction method ensures you receive the triterpenes and polysaccharides that traditional Chinese medicine has valued for over 2,000 years. The clean formulation contains no fillers, flowing agents, or unnecessary additives that could interfere with absorption.

    LACTOSE FREE
    GLUTEN FREE
    NON-GMO
    VEGAN
  • Lab Testing Results / Certificate of Analysis (COA)

  • Frequently asked questions

    1. Can I take Poria with Lion's Mane and Reishi?

      Yes, Poria combines well with Lion's Mane and Reishi since they target different pathways. Poria covers immune and digestive support, Lion's Mane focuses on cognition, and Reishi on stress response and sleep.

    2. How much Poria powder should I take daily?

      Poria Mushroom Extract is typically dosed at 500,1000mg daily in 1-2 doses; start low to assess tolerance, and use a milligram scale since no scoop is included. It's standardized to 55% beta-glucans for consistent potency.

    3. How long does Poria take to work?

      Poria mushroom extract typically takes 2-3 weeks to reach peak effects, though some users notice initial digestive and immune support benefits within the first week as beta-glucans and pachymic acid accumulate.

    4. How does Poria's 55% beta-glucan standardization work?

      Our Poria Mushroom Extract is standardized to contain exactly 55% beta-glucans through precise extraction and testing methods, ensuring consistent potency in every batch. We use whole fruiting body extraction rather than just the inner white portion like many competitors, which provides a broader spectrum of beneficial compounds while maintaining the guaranteed 55% beta-glucan content.

    5. Are there side effects from Poria Mushroom extract?

      Poria mushroom extract is generally well-tolerated at recommended doses, though large amounts may cause mild digestive discomfort, so starting low is wise. Ours is standardized to 55% beta-glucans and third-party tested for purity.

    6. Can I stack Poria with other mushroom supplements?

      Yes, Poria stacks well with other mushroom supplements since each species offers unique bioactive compounds. Our Poria is standardized to 55% beta-glucans and contains pachymic acid, complementing the polysaccharides and triterpenoids in Lion's Mane, Reishi, or Cordyceps.

    7. Why choose Nootropics Depot's whole fruiting body Poria?

      Our Poria uses the whole fruiting body, not just the inner white portion, delivering a broader spectrum of triterpenoids, monosaccharides, and pachymic acid, standardized to 55% beta-glucans with batch testing for consistent potency.

    8. When will Poria Mushroom powder be back in stock?

      We don't have a specific restock date for Poria Mushroom Extract Powder at this time. We recommend signing up for restock notifications on the product page, as we typically update inventory status within 24-48 hours of receiving new batches.

Trust Through Transparency

Your health matters, which is why we only use the best 3rd party ISO accredited labs and cGMP certified and FDA registered facilities right here in the USA

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