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Lactose Free Gluten Free
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Lactose Free Gluten Free

Smart PS™ Phosphatidylserine Softgels

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label-lactose-free:
true
label-gluten-free:
true
label-gmo-free:
false
label-vegan:
false
label-vegetarian:
false
info-dose:
500mg (One Capsule)
info-dose-timing:
Flexible
info-dose-frequency:
1 Time Daily
info-how-to-take:
With Or Without Food
benefits-effect-days:
2-3 Weeks
Benefits:
Mood
Benefits:
Memory
Benefits:
Stress
Benefits:
Cognition
product-summary:
  • Enhances Cognitive Function
  • Regulates Cortisol Levels
  • Helps Support Mood
  • Improves Memory
page-fact-checked:
false
Type:
Softgels
Type:
Adaptogens
Type:
Choline Supplements
Type:
Nootropics
disable-paypal:
false
lab-testing:
SPSCS1010824 | SPSCS1010824_120ct_Signed.pdf
lab-testing:
SPSCS1062023 | SPSCS1062023-60ct_signed.pdf
lab-testing:
SPSCS1020224 | SPSCS1020224_60ct_signed.pdf
$29.99
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Product Usage

Dose Dose

500mg (One Capsule)

Dose Timing Dose Timing

Flexible

How to Take How to Take

With Or Without Food

Dose Frequency Dose Frequency

1 Time Daily

Benefits

Time to notice full effects: 2-3 Weeks

  • Mood Mood
  • Memory Memory
  • Stress Stress
  • Cognition Cognition

Buy Phosphatidylserine Softgels

Differences Between Smart PS™ and Smart PS™ Green

Smart PS is a phosphatide complex that contains a blend of Phosphatidylserine, Phosphatidylcholine, and Phosphatidylethanolamine. Smart PS Green contains Phosphatidylserine only and is a soy-free variation of Smart PS derived from sunflower.

What is Phosphatidylserine?

Phosphatidylserine (PS) is a phospholipid that is a major component of cell membranes, making it a highly valuable nutrient for supporting cognitive function. Without sufficient levels of phosphatidylserine, brain cells may not transmit nerve impulses properly.

Phosphatidylserine is highly unstable and therefore prone to degradation. To overcome the issue of phosphatidylserine stability, enter Smart PS™ — an exclusive fluid dispersion of phosphatidylserine material, provided as finished dosage softgels, which has enviable stability. Shelf-life studies on Smart PS™ found that even after 24 months, the material showed absolutely no degradation. Smart PS™ Softgel Capsules are soy-derived. For those that are sensitive or allergic to Soy, we now also have a soy-free formulation that is derived from sunflower, called Smart PS green. Smart PS green still boasts the same great stability and bioavailability that is characteristic of soy derived Smart PS, allowing you to reap the same benefits, without the soy!

Smart PS™ enhanced-stability phosphatidylserine softgels overcome the problem of phosphatidylserine degradation for maximum brain benefits.* Smart PS™ finished dosage softgels feature an exclusive fluid dispersion phosphatidylserine material that has significantly enhanced stability for maximum brain benefits.*

Phosphatidylserine Benefits and Uses

    • May help promote cognitive function*
    • May help support feelings of well being*
    • May help support energy*
    • May help promote healthy sleep habits*

Phosphatidylserine vs Phosphatidylcholine

As phospholipids, both Phosphatidylserine (PS) and Phosphatidylcholine (PC) are major components of cell membranes. However, unlike phosphatidylserine, phosphatidylcholine has very limited value in improving mental function. Why? Weak bioavailability. As a nutritional supplement, Phosphatidylcholine is hoarded by the liver. As a result, hardly any of it actually makes it to the brain. Phosphatidylserine, on the other hand, is a modified form of phosphatidylcholine that does get to the brain, making it a highly valuable nutrient for enhancing cognitive function. Phosphatidylserine benefits may promote cognitive function, support energy, promote feelings of well being, and healthy sleep habits. However, phosphatidylserine sleep benefits have only been found in limited clinical trials.

What is Phosphatidylcholine?

Phosphatidylcholine is a phospholipid with two fatty acids bound to a glycerol backbone and are a major component of cell membranes. It is found in the highest concentrations within the liver and the brain. Phosphatidylcholine benefits are derived from the fact that it is a choline source and that a phosphatidylcholine supplement may enhance the production of acetylcholine in neurons, which ultimately promotes cognitive function. Yet, Phosphatidylcholine benefits are hard to achieve due to its poor bioavailability. Phosphatidylcholine benefits were noted in a trial aiming to reduce localized fat relative to baseline data. However this was only achieved through injection and results were inconsistent. Membrane mediated cell signaling and phosphatidylcholine transfer protein activation is believed to be the bulk of phosphatidylcholine function.

Fortunately, Phosphatidylcholine and Phosphatidylserine benefits can be easily reaped with Smart PS™ softgels. Phosphatidylserine is a modified form of Phosphatidylcholine that actually reaches the brain. Pharmacokinetic studies show that supplemental Phosphatidylserine easily crosses the blood-brain-barrier, making it a highly valuable nutrient for promoting cognitive function.*

Research in Animals and in Humans has shown that Phosphatidylserine (PS) May:

    • Support mood
    • Support cognitive function
    • Enhance athletic performance and recovery

Phosphatidylserine Dosage

As a dietary supplement, take one 100mg  Smart PS™ or Smart PS™ Green softgel daily.

Phosphatidylserine Reviews

To gain more insight, see the Phosphatidylserine supplement reviews and experiences below.

Where to buy Phosphatidylserine Supplement

Nootropics Depot offers 60ct and 120ct jars of high quality Phosphatidylserine. Nootropics Depot’s Phosphatidylserine has been lab-tested and verified for both product purity and identity.

 

 *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

*Smart PS Contains Soy Allergens. Smart PS Green contains Phosphatidylserine only and is a soy-free variation of Smart PS derived from sunflower.

Reviews

  • 5
    PS Softgels

    Posted by Tom on 9th Apr 2023

    Used daily and it makes a difference.

  • 5
    Smart PS Green (soy free) Phosphatidyle Serine

    Posted by Carolyn on 16th Jan 2023

    I love this product, a mood elevator, as the sun is reduced in winter where I live. D3 is essential for bone and mood; however, this supplement is beyond that. To metabolize, the gel cap crosses the blood-brain barrier (powdered-filled capsules do not). Dosing to support you, to be at the top of your game, Supporting mood elevation of brain hormones of dopamine, serotonin, and norepinephrine. Engages typically in one hour. You do not have to take it daily. It is terrific for retaining and recalling, used in scholastic studies, i.e., preparing for exams. Offering you the ability to focus when over-stressed or with the aging process and associated fatigue. Great for lack of concentration. Suggest not taking after 4 pm unless you plan for evening alertness— assured no feeling of over-excitement or jittery stimulation. See evidence-based research to support Phosphatidyl Serine use further.

  • 5
    Smart PS

    Posted by Pat H on 17th Dec 2022

    This product definitely helps to calm my overactive ADD brain.

  • 5
    I take a lot of supplements and prefer to build my own "stack" rather than buy things I don't need or filler. I added Smart PS Softgels to my morning and night stack to help memory and facial recognition. After about two weeks I have noticed improv

    Posted by Helen on 17th Aug 2022

    I use Nootropics Depot because they are fast and dependable and I trust them, I only wish they would bring back piracetam!

  • 5
    Laster sharp focus and cortisol control support

    Posted by Coach T on 24th Jun 2022

    This is one of those supps that if I stop taking, I notice a drop in cognitive performance pretty quick. It keeps me sharp through the afternoon without having to take any caffeine.

  • 2
    Foggy brain

    Posted by Manny on 3rd Apr 2022

    Heard a lot of great benefits regarding PS; however when I used it, I consistently experienced foggy brain. I wonder if 100mg is too high of a dose for me? I was originally introduced to PS through BulkSupplements powder form and had good relatively good effects (e.g., slept better, had more mental energy throughout the day, etc). I don’t doubt the quality from ND, just for some reason didn’t have the best results with their formulation(?).

  • 5
    Wow.

    Posted by Daniel Cutts on 16th Sep 2021

    Best choline supplement ever! They even came with n ice pack and said they need to be refrigerated!! Nootropics Depot is the BEST!

  • 5
    Works well.

    Posted by Ryan Martin on 12th May 2021

    I take PS before bed and it works well. It’s not incredibly noticeable but I feel less stress and more calm.

  • 5
    Day 1 thoughts

    Posted by Mick Mc Monagle on 28th Jan 2021

    Tried smart PS green with the recommended dosage. Last dose was about 7.30pm along with zinc, mag and l theanine. I definitely experienced deeper sleep to the extent I missed my alarm! Next day I had a feeling of tiredness but can't say it's the reason. Felt nice sense of calm when taken during the day. I will share my thoughts again after a week or two. Currently starting oxiracetam, PS, alpha GPC and shilajit

  • 5
    Exceeded my expectations

    Posted by Daniel on 7th Oct 2020

    This is an underrated product for sure. I noticed an improvement in my learning and work performance. It took about a week to build up but I can honestly say I noticed this one a bit stronger than some of the similar nootropics that get all kinds of hype. I stacked this with Cognizin also from ND, and that was a great combination for me. I recommend.

  • 5
    Very nice

    Posted by Scott on 23rd Aug 2020

    taken daily, this thing really has slowly but surely improved my cognition performance at work

  • 5
    Lowers Stress and Helps Sleep

    Posted by Michael Harris on 4th Jun 2020

    This is better than your average cheap PS gotten off Amazon. After two days I began to notice improved sleep. If I forget to take this at night I can tell because I tend to wake up earlier in the night/morning than if I take my PS. This seems to have a pretty strong effect on lowering cortisol. I'll be buying my PS from nootropics depot from now on.

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*Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.