R-ALA Cyclodextran Powder
I use R-ALA Cyclodextran to relieve the burning sensation I get with peripheral neuropathy in my feet and it works very well for fee.
R-ALA cyclodextrin is the ultimate alpha lipoic acid (ALA) formulation for bioavailability and stability! This formulation is made by loading R-ALA into a cyclodextrin shell, which both helps protect the ALA in addition to boosting the absorption. The end result is ALA with ideal bioavailability to help you combat oxidative stress and inflammation while also helping to promote metabolic health!*
R-ALA Cyclodextrin is a highly optimized formulation of alpha lipoic acid (ALA). ALA is naturally found in the mitochondria of cells, where it plays a crucial role in energy production by protecting the mitochondria from oxidative stress. ALA can be found in some fruits and vegetables but has limited bioavailability. Most importantly, two distinct versions of ALA exist. R-ALA and S-ALA. R-ALA is the most commonly occurring natural form, and absorbs quite well, yet is plagued by instability. S-ALA on the other hand is a lot more stable but has very limited bioavailability. Due to this, R-ALA is the most desirable form of ALA, but in order to utilize this form, we need to stabilize it.
The most common stabilization technique is creating a sodium ALA salt, which is referred to as Na-R-ALA. This form has great stability and bioavailability, however an even better stability enhancement technique exists! Instead of stabilizing R-ALA with sodium, we can also microencapsulate it with a highly specialized starch called cyclodextrin. By loading R-ALA into these cyclic starches, R-ALA stability is drastically improved, as is the bioavailability.
Keep reading to find out how Cyclodextrin changes the game!
One of the primary benefits of R-ALA Cyclodextrin is balancing oxidation levels!* R-ALA is well known for its ability to attenuate oxidative stress through multiple different pathways, making it a very capable oxidation regulating compound! One of the ways in which ALA regulates oxidative status, is by combating reactive oxygen species (ROS), which it achieves by directly interacting with ROS, while also helping to enhance levels of important endogenous compounds and vitamins like glutathione, vitamin C and vitamin E, that also regulate ROS.
A particularly interesting effect here is that ALA also appears to be a potentiator of vitamin C, by helping vitamin C get into mitochondria where it can exert its antioxidant effects. This means that ALA can be highly synergistic with vitamin C supplementation! In addition to this, R-ALA also supports mitochondrial enzyme activity and acts as a metal chelator which can help mitigate metal mediated peroxidation and ROS formation.
Another fascinating aspect of ALA supplementation is its effects on metabolic health. One of the most interesting mechanisms here is that through neurological pathways, ALA can actually help decrease appetite! This could be great for someone looking to lose some weight, who needs a bit of help controlling their appetite. On a more cellular level, ALA also helps promote healthy glucose processing and most importantly, appears to quite significantly increase metabolic rate. Pair this with the appetite reduction effects, and it becomes clear that R-ALA cyclodextrin is an excellent metabolic aid!
The Metabolic Stack: R-ALA Cyclodextrin + Sesame Extract Capsules
Alpha lipoic acid stacks exceptionally well with sesamin for specifically enhancing metabolic function. This effect is even more pronounced when stacking the highly optimized R-ALA cyclodextrin with sesamin!*
The Mitochondrial Stack: R-ALA Cyclodextrin + Acetyl L-Carnitine
Combining R-ALA cyclodextrin and Acetyl L-Carnitine creates a synergistic effect for mitochondrial function. These two dietary supplements are able to promote mitochondrial density and overall mitochondrial function when used in tandem. This is not a stack you want to miss!*
The Balanced Oxidation Stack: R-ALA Cyclodextrin + Reduced Glutathione Tablets
When we think of Reduced Glutathione, we immediately think of its incredible effects on oxidative stress. To support balanced oxidation levels even further, adding R-ALA Cyclodextrin to the mix creates the perfect stack with the purposes of mitigating oxidation!*
As a dietary supplement, take 500mg of R-ALA Cyclodextrin daily.
To gain more insight, see the R-ALA Cyclodextrin reviews and experiences below.
Nootropics Depot offers 30g or 60g jars of high-quality R-ALA Cyclodextrin. Nootropics Depot’s R-ALA Cyclodextrin has been lab-tested and verified for both product purity and identity.
| *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. |
I use R-ALA Cyclodextran to relieve the burning sensation I get with peripheral neuropathy in my feet and it works very well for fee.
I started taking ALA in high doses after learning about how it can essentially repair the liver. I was trying to mimic the effects of IV ALA treatment. I put 1/4 - 1/2 tsp under my tongue anywhere from 2-15 times over the course of a morning. Even a couple of doses like that provide a noticeable boost in energy and mental clarity. But too much too late in the day will keep me awake at night. It tastes good, mild. I tried the S-ALA and it tastes awful!
I use R-ALA Cyclodextran to relieve the burning sensation I get with peripheral neuropathy in my feet and it works very well for fee.
I started taking ALA in high doses after learning about how it can essentially repair the liver. I was trying to mimic the effects of IV ALA treatment. I put 1/4 - 1/2 tsp under my tongue anywhere from 2-15 times over the course of a morning. Even a couple of doses like that provide a noticeable boost in energy and mental clarity. But too much too late in the day will keep me awake at night. It tastes good, mild. I tried the S-ALA and it tastes awful!
This product was delivered with a cold packet in special packaging. However it does not state anywhere on the container if I am to keep this product in the refrigerator after opening? ND Admin: No need for special storage conditions. We just put it in there in the summer because of how hot it can get here in Arizona.
powder exactly as described, quick delivery and excellent packaging
Definitely the best form of r-ala
Many years ago, I was diagnosed with "Bacterial Dysbiosis with Malnutrition." In other words, my digestive tract was unable to metabolize proteins, carbohydrates, fats, and nutritional supplementation. This was discovered from the results of a thorough cellular analysis called a "micro-nutrient blood test" from Spectracell Laboratories. It also revealed (in capital letters) that there were undetected amounts of "glutathione and R-Alpha-Lipoic Acid." These are the mother and father of all antioxidants! So for the last four years, my supplements had to be in the form of liposomal and nano-particle size delivery. This way they bypassed the digestive tract and went straight to the bloodstream. And then I took a chance on Nootropics Depot R-ALA Cyclodextrin powder. and never looked back. I take it the way the third reviewer suggested: 1/4 measured tsp directly on my tongue - no water. The taste is a little peppery and melts quickly. Along with this I keep my powerful glutathione level optimal with N-Acetyl-L-Cysteine, L-glutamine, L-glycine, vitamins C,E and nano-particle size liquid selenium and silver. The Best Health To You All!!
Great stuff
Great product. Easy to use...i feel great too
I had yet another concussion a couple of months ago. I played football for 11 years and now get concussed quite easily. I read online that ALA is good for brain inflammation, so I sought out the highest quality ALA I could find. I can gratefully report that the Nootropics Depot R-ALA Cyclodextrin powder has noticeably reduced my symptoms. I'm finding it easier to exert myself cognitively. I also happen to like the flavor. It has a nice savory taste to it. I put it right on my tongue and let it dissolve a bit, swallowing it without water. You can't do that with most supplements. I'd recommend anyone looking to counter neurological inflammation give it a try.