Alpha Lipoic Acid (ALA) is a fatty acid that exists naturally in our mitochondria, where it promotes healthy levels of oxidation. Alpha Lipoic Acid is present in some fruits and vegetables, however, Alpha Lipoic Acid is notorious for having very low bioavailability and stability. One way to improve on this, is by selecting the most active enantiomer, R Alpha Lipoic Acid (R ALA) and then stabilizing it. In the past, this has been done with Sodium to create Sodium R Alpha Lipoic Acid (Na-R-ALA) which shows excellent stability and bioavailability. However, stabilizing R Alpha Lipoic Acid (R ALA) within a cyclodextrin complex, to create R ALA Cyclodextrin, dramatically enhances the bioavailability and stability of R Alpha Lipoic Acid, significantly more than a Sodium stabilization. This makes R ALA Cyclodextrin, arguably one of the best supplements for promoting healthy oxidation levels especially within the Mitochondria. With all this being said, what we really want to know is what does Alpha Lipoic Acid do?
Studies found that R ALA plays an important role in energy production and also promotes healthy oxidation levels. R ALA has been found to be a more potent form of alpha lipoic acid than S ALA and much better at promoting healthy metabolic function. However, one drawback of R ALA, is that it is quite unstable and thus it is not absorbed well in its pure form. This is why stabilizing R ALA is essential for creating a high bioavailability alpha lipoic acid supplement.
Cyclodextrin use has been widely researched to improve the bioavailability of certain compounds. Several studies have shown that the combination of R ALA with a cyclodextrin supplement significantly increases the bioavailability of R ALA, which is in part due to the extraordinary stabilization ability of cyclodextrins. Studies have shown that cyclodextrin far outperforms sodium as a stabilizer for R ALA, which is very impressive as Na R ALA is already very stable!
Studies found that R Alpha Lipoic Acid Cyclodextrin is easily absorbed in the intestine, making R ALA Cyclodextrin an effective method for delivering Alpha lipoic acid whilst also making it more bioavailable. Clinical trials have discovered that alpha lipoic acid helps promote brain health and healthy metabolic function and even shows some efficacy, though not too significant at supporting organ health.
To further take advantage of R Alpha Lipoic Acid benefits, R Alpha Lipoic Acid Cyclodextrin can be combined with Acetyl L-Carnitine in order to take advantage of the synergistic effects between the two dietary supplements. The combination of Alpha Lipoic Acid and Acetyl L-Carnitine, in particular has a potent effect on increasing Mitochondrial density and may support mitochondrial function.
As a dietary supplement, take 500mg of R-ALA Cyclodextrin powder once daily.
To gain more insight, see the R-ALA Cyclodextrin Complex powder reviews and experiences below.
Nootropics Depot offers 30g or 60g jars of R-ALA Cyclodextrin Complex powder. Nootropics Depot's R-ALA Cyclodextrin Complex has been lab-tested and verified for both product purity and identity.
ATTENTION: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
I started taking ALA in high doses after learning about how it can essentially repair the liver. I was trying to mimic the effects of IV ALA treatment. I put 1/4 - 1/2 tsp under my tongue anywhere from 2-15 times over the course of a morning. Even a couple of doses like that provide a noticeable boost in energy and mental clarity. But too much too late in the day will keep me awake at night. It tastes good, mild. I tried the S-ALA and it tastes awful!
This product was delivered with a cold packet in special packaging. However it does not state anywhere on the container if I am to keep this product in the refrigerator after opening? ND Admin: No need for special storage conditions. We just put it in there in the summer because of how hot it can get here in Arizona.
I started taking ALA in high doses after learning about how it can essentially repair the liver. I was trying to mimic the effects of IV ALA treatment. I put 1/4 - 1/2 tsp under my tongue anywhere from 2-15 times over the course of a morning. Even a couple of doses like that provide a noticeable boost in energy and mental clarity. But too much too late in the day will keep me awake at night. It tastes good, mild. I tried the S-ALA and it tastes awful!
This product was delivered with a cold packet in special packaging. However it does not state anywhere on the container if I am to keep this product in the refrigerator after opening? ND Admin: No need for special storage conditions. We just put it in there in the summer because of how hot it can get here in Arizona.
powder exactly as described, quick delivery and excellent packaging
Definitely the best form of r-ala
Many years ago, I was diagnosed with "Bacterial Dysbiosis with Malnutrition." In other words, my digestive tract was unable to metabolize proteins, carbohydrates, fats, and nutritional supplementation. This was discovered from the results of a thorough cellular analysis called a "micro-nutrient blood test" from Spectracell Laboratories. It also revealed (in capital letters) that there were undetected amounts of "glutathione and R-Alpha-Lipoic Acid." These are the mother and father of all antioxidants! So for the last four years, my supplements had to be in the form of liposomal and nano-particle size delivery. This way they bypassed the digestive tract and went straight to the bloodstream. And then I took a chance on Nootropics Depot R-ALA Cyclodextrin powder. and never looked back. I take it the way the third reviewer suggested: 1/4 measured tsp directly on my tongue - no water. The taste is a little peppery and melts quickly. Along with this I keep my powerful glutathione level optimal with N-Acetyl-L-Cysteine, L-glutamine, L-glycine, vitamins C,E and nano-particle size liquid selenium and silver. The Best Health To You All!!
Great stuff
Great product. Easy to use...i feel great too
I had yet another concussion a couple of months ago. I played football for 11 years and now get concussed quite easily. I read online that ALA is good for brain inflammation, so I sought out the highest quality ALA I could find. I can gratefully report that the Nootropics Depot R-ALA Cyclodextrin powder has noticeably reduced my symptoms. I'm finding it easier to exert myself cognitively. I also happen to like the flavor. It has a nice savory taste to it. I put it right on my tongue and let it dissolve a bit, swallowing it without water. You can't do that with most supplements. I'd recommend anyone looking to counter neurological inflammation give it a try.
