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Dose
25mg (One Capsule)
Dose Timing
Flexible
How to Take
With Or Without Food
Dose Frequency
1-2 Times Daily
7,8-Dihydroxyflavone (7,8-DHF) is a natural flavone that crosses the blood-brain barrier, potentially improving mood, enhancing cognitive function, supporting memory, and reducing oxidative stress through antioxidant enzyme activation.
Time to notice full effects: 2-3 Weeks (With Immediate Effects)
Mood
Cognition
Memory
Oxidation
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7,8-Dihydroxyflavone, also known as 7,8-DHF, is a natural flavone found in a number of species that can reach the brain and exert cognitive effects. It binds to the TrkB receptors in a similar way to BDNF, or brain derived neurotrophic factor. When the TrkB receptor is activated, neuroprotective and neurogenetive effects occur in neurons, which tend to affect the dendrites. Dendrites are what reach out from the neurons into the synapse to participate in signaling with other neurons. 7,8-DHF has been shown to promote the growth of these dendrites, and to help restore communication between neurons in animal models. Other natural extracts, like polygala tenuifolia and bacopa monnieri work in a similar fashion, but rather than binding directly to the TrkB receptor, they cause a release in BDNF, which then binds to the receptor. 7,8-DHF has also demonstrated a protective effect against apoptosis. 7,8-DHF can cross the blood brain barrier, and act directly on brain TrkB receptors; which is something that peripheral administration of BDNF cannot do. As such, it is a very promising natural compound for cognitive function.
As a dietary supplement, take one to two 25mg capsules of 7,8 Dihydroxyflavone daily. It appears to be subject to extensive first-pass metabolism in the liver.
To gain more insight about 7,8 Dihydroxyflavone, read the 7,8 DHF reviews and experiences below.
Nootropics Depot offers 60 count or 120 count jars of 7,8-Dihydroxyflavone Capsules. Nootropics Depot's 7,8 DHF Capsules have been lab-tested and verified for both product purity and identity.
| *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
As others noted subtly uplifts alert and focus. For the whole day. Paired with Alpha GPC for a really good workout. Took early afternoon but still felt the up affects till late evening. Tried again the next morning but caused complete burnout , lethargic feeling. Completely stops working and causes opposite effect next day. Seems like this is a take only once in a while med for me.as whatever metabolic systems it is utilizing get burned out
7,8DHF is one of those impressive and surprising supplements. It is potent enough that, in my experience, you should be careful when stacking it with other supplements. To me, it feels like something one could use if they have a slight short attention span. If you're not sure which nootropic to try because you tend to not get any effects, I believe 7,8DHF is something to explore a bit. As always, NootropicsDepot quality is without match and you should order it here to get a taste of the real thing.
very good product
Keeps the brain quite spry.
i think it's good enough
I liked it by itself, but when I combine it with Cordyceps (both 10:1 and 1:1) I get nice smooth energy, a very positive mood, and a delicious calmness with what feels like dopamine chills when I take OTC pseudophedrine timed release with it for my pollen allergies.
I tend to be sensitive to supplements and this really felt similar to n-pep-12. Taking this on carnivore is 5x better. I noticed when not on carnivore it gave me a little difficulty focusing as if I had ADHD.
I have been actively experimenting with various Nootropics and supplements since the early 2000's wild west days. Most of the compounds I have tried were either a disappointment, or provided exciting results that could not be sustained over time or produced side effects that forced me to drop them from my regimen. Aniracetam is the only thing that's been a staple for most of that time. This stuff is amazing. I keep waiting for the law of diminishing returns to kick in, but it hasn't yet after more than 60 days of daily use. I'm a recovering alcoholic, so I personally feel like this product has helped me to regain some of my cognitive function lost as the result of 15 years of vodka for breakfast lunch and dinner. In many ways I feel more mentally youthful - I am excited about listening to new music, reading new books, learning new things. Can't say enough good things about 7,8 DHF and ND in general. They are the ONLY place to order compounds like this for me.
Taking 2 caps of 7,DHF seems to boost mood subtly but considerably. I feel the effects come on pretty slowly, but surely. Works better for me than tianeptine ever did. Goes well with tongkat too, but it's plenty powerful by itself.
I like this stuff. I'm surprised there isn't more hype about it. Helps keep my mind focused and my mood uplifted. It's subtle, but it works.
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