L-arginine alpha ketoglutarate, shortened simply to AAKG, is comprised of two important compounds to your health. Arginine is a semi-essential or conditionally essential amino acid, meaning that it is necessary to proper health and bodily functions but can only be created in the body under specific situations. Normally, it comes from supplements or from diet sources, including soy beans, peanuts, pumpkin seeds, dairy products, and poultry and other lean cuts of meat. Alpha ketoglutarate is an important compound created during the Krebs cycle, which breaks down molecules to create a pool of energy.
When combined, alpha ketoglutarate has actually been shown to increase the intestinal uptake of arginine. AAKG presents a wide range of potential benefits and uses that may improve your health and wellbeing.
AAKG 2:1 benefits most commonly involve supplementation for bodybuilding and athletic performance. Studies suggest that AAKG may effectively help the liver neutralize ammonia and other harmful substances, which should make for less pain, less muscle fatigue, and longer workouts. Arginine may also be beneficial for its role in building protein. Creating various protein chains is necessary for developing larger, stronger muscles and repairing damaged muscle tissue. In studies, arginine has also been associated with increased insulin production. Increased insulin has been found to assist in creating greater muscle growth and strength.
Arginine is also prized for its potential to increase nitric oxide activity. Increased nitric oxide production may lead to wider blood vessels, which in turn may result in increased blood flow. This means more oxygen and nutrients to muscles and organs. Wider blood vessels also means more carbohydrates, protein chains, and muscle building hormones. All of this may result in greater physical performance, enhanced workout capacity, improved endurance, and reduced recovery times.
Studies have also found that arginine may help to promote a healthy immune system. Alpha ketoglutarate supplementation may also positively effect how your body handles amino acids during states of impaired protein metabolism. Some studies suggest that alpha ketoglutarate may improve intestinal health, possibly by helping in the process of metabolizing glutamine, which has been shown to:
- Fuel the immune system in your intestines
- Enhance immune responses and functions during physical trauma
- Promote protein turnover when you’re in a malnourished state
The human body requires arginine for various functions, but it is most important for eliminating ammonia, which is toxic to the human body, by controlling the urea cycle. Arginine is a key component of building protein and is also converted into nitric oxide, which causes blood vessels to dilate.
Alpha ketoglutarate is a derivative of glutaric acid. While acting as an intermediary in the Krebs cycle, alpha ketoglutarate also plays a key role in cell growth and healing from injuries. During normal protein turnover or when you take in a lot of protein, alpha ketoglutarate takes on nitrogen from amino acids, turning into glutamate. Glutamate then contributes to the urea cycle, which involves the breakdown of protein to produce urea, a waste compound that is flushed away in urine. Alpha ketoglutarate can also generate arginine on its own through transamination reactions.
As a dietary supplement, take 2600mg of AAKG 2:1 once daily.
Nootropics Depot offers 125g or 250g jars of high quality AAKG powder. Nootropics Depot's L-Arginine A-Ketoglutarate has been lab-tested and verified for both product purity and identity.
For more information see the AAKG Wiki.
To gain more insight, read the AAKG reviews and experiences below.
Attention: This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.