Cognizin Citicoline Powder

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Cognizin Citicoline
30g or 60g
120 Servings or 240 Servings
As a dietary supplement, take 250mg of Cognizin Citicoline 1-2 times daily.
Store in a cool and dry place. Keep away from direct sunlight and heat.
In an effort to use more appropriate materials for certain products, we will be phasing in different bottles that contain HDPE vs PET. As we make this transition you may receive a bottle that is different in color and material than that pictured.
Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.
Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases. These statements have not been evaluated by the Food and Drug Administration.
This product does not include a scoop. Transfer scoops are not an accurate form of measurement. A milligram scale is needed to accurately measure this product.

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Cognizin Citicoline Powder

What is Citicoline?

Citicoline, a popular nootropic supplement that is also known as CDP choline (cytidine diphosphate choline), is an organic molecule produced endogenously and is found in all living cells. The two major components of Citicoline are Choline and Cytidine (Cytidine is converted to Uridine in the body). CDP choline is a precursor for the synthesis of important phospholipids. These phospholipids are essential to cell membranes including phosphatidylcholine, phosphatidylserine, and phosphatidyl-ethanolamine. Phospholipids must be continuously synthesized for adequate function of cells due to their high turnover rate.

What is Cognizin?

Cognizin is a patented, clinically trialed form of Citicoline. Citicoline is found in every cell of the body and especially vital to our brain health and cognitive function. Unlike artificial stimulants that ramp up energy and attention levels only to have those levels come crashing down later, a Cognizin Citicoline supplement provides nutritional support that benefits:

  • our mental processes*
  • enhances our focus and concentration*
  • supports healthy brain metabolism*

Cognizin Citicoline provides the nutrients needed to support cognition, attention and focus.*

Citicoline Benefits and Uses

Citicoline benefits and uses may include:

  • Support cognitive function
  • Promote focus and mental energy
  • Support healthy stress levels
  • Promote faster recall speed
  • Support memory formation
  • Promote learning capacity


How Does Cognizin Citicoline Powder Promote Cognitive Function?

  • Cognizin citicoline promotes electrical impulses in the brain, supports our healthy brain cells and protects neurons from free radical damage.*
  • Cognizin citicoline promotes cognitive function by regulating healthy level of acetylcholine*
  • Cognizin citicoline promotes healthy mitochondrial function*
  • Cognizin citicoline supports the synthesis and maintenance of cell membranes.*

Cognizin and Phospholipids

Cognizin Citicoline supports vital nutrients required to support your body's regeneration of Phospholipids. This is important because:

  • Phospholipids make up 30% of our brain tissue
  • Phospholipids provide essential protection for neurons
  • Phospholipids support neural communication 

Cognizin Citicoline Research and Clinical Studies

Cognizin has been studied in a variety of human clinical trials. The most recent human clinical trial focused on the benefits of Cognizin on healthy, middle-aged men and women. Conducted at the Brain Imaging Center at McLean Hospital, researchers found increases in brain activity among participants that had taken a Cognizin supplement for six weeks. Of particular note, differences were noticeable in those participants that performed tasks that required sustained attention.

Clinical trials have also found that Cognizin citicoline supports healthy mitochondrial function. These powerhouses within our cells are what actually produce the brain’s energy.* Healthy mitochondrial function results in higher levels of ATP (Adenosine triphosphate)— our bodies primary energy storage molecule—in brain cells. 

Cognizin Citicoline Infographic #1

Cognizin Citicoline Infographic #2

Citicoline as a Natural Nootropic Supplement

Citicoline is commonly paired with dietary supplements or nootropic compounds in various nootropic stacks.

Why Choose Cognizin as Your Preferred Choline Supplement?

Clinically tested for its efficacy, Cognizin is a patented form of citicoline that supplies your brain with the energy it needs to stay sharp.* Cognizin Citicoline is also:

  • pure
  • vegetarian
  • allergen-free
  • GRAS (generally recognized as safe)
  • stable and effective 

Cognizin Citicoline Dosage

As a dietary supplement, take 250mg of Cognizin Citicoline 1-2 times daily.

Cognizin Reviews

To learn more, read the Cognizin Citicoline reviews and experiences below.

Where to Buy Cognizin Citicoline Powder?

Nootropics Depot offers 30g or 60g jars of high quality Cognizin Citicoline powder. Nootropics Depot's Cognizin Citicoline has been lab-tested and verified for both product purity and identity.

You may also be interested in Cognizin Citicoline capsules

ATTENTION: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

29 Reviews

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  • Joyee Sen - 20th Jan 2022


    Even with 100 mg I feel a very noticeable difference in my cognition. Don't see any build of tolerance either, after 4 weeks. Very powerful stuff for general mental acuity, energy, sharpness and focus.

  • Lawrence L Turner JR - 8th Nov 2021

    Cognizin citicoline powder

    Great product

29 Reviews

  • Joyee Sen - 20th Jan 2022


    Even with 100 mg I feel a very noticeable difference in my cognition. Don't see any build of tolerance either, after 4 weeks. Very powerful stuff for general mental acuity, energy, sharpness and focus.

  • Lawrence L Turner JR - 8th Nov 2021

    Cognizin citicoline powder

    Great product

  • easy_does_it - 3rd Aug 2021

    Going on 6 months, intermittent schedule

    Honestly, because this is not the only supplement I take, and also do not take on a regular basis, it is not possible to conclude that the positive mind concentration effect and nimbleness are due to it or due to the ginkgo biloba, or the alha-gpg or the Neurodrive (from another shop) I am also taking, or just plain B vitamin complex. This is the reason why one should refer to the scientific literature.

  • Adam - 17th Jul 2021


    I have purchased Cognizin several times and I have finally decided to write a review. I have taken it for the last year and can honestly say that it will provide you with a tangible, yet minor, boost in mental performance. I used it to great effects this year in finishing my bachelor’s degree. I think it helps with focus as well as retention. It isn’t miraculous and won’t cure you of serious neurological issues, but a little bit of this sprinkled into your coffee each morning will have you well on your way to an effective and impactful day.

  • Aaron Leos - 11th Jun 2021

    Important Brain Chemical!

    I find this is the best formulation of choline on the market! It's important to consider that when taking certain AMPA activating chemicals the depletion of choline is normal, so you need to supplement with this, and it passes the blood-brain barrier!

  • Brent Braten - 22nd Mar 2021


    Well, I bought upon the recommendation of a friend. I really don't know how it tastes because I can't taste much but I do know that the water tastes slightly off. I didn't notice anything right away but over the course of the past few weeks a number of connections have been made between events that took place almost 35 years ago and current international events so I will say that it is helping in ways that I do not fully understand.

  • Ron - 4th Feb 2021

    Cognizin Citicoline Powder

    Great product at a great price.

  • Kevin Westlake - 20th Jan 2021

    The best choline source on the market IMHO

    Not only does Citicoline/CDP Choline give a potent and robust clean choline source (an essential) but it has a mood effect that is hard to miss, depending on your stack. I would use this only at 600mg daily, but because of it's price I pair it with Centrophenoxine. 150mg of each, twice daily feels spot on for my current stack. I must add that, despite it's cost, Nootropics Depot are both the cheapest I have found from any genuine site and their products have so far NEVER let me down in terms of quality!

  • Jason R - 12th Aug 2020

    Feel like it works

    Feel like it works

  • Riley - 30th Jul 2020

    Good need pretty high dose to get good results tho

    I like the product

  • Sean Fitzgerald - 21st Jun 2020


    I find I get alot less headaches when I take this. Memory has improved alot

  • Juan - 16th May 2020


    Fantastic quality as always from Nootropics Depot.

  • Jonathan Miller - 19th Dec 2019

    Love it when you get what you paid for

    If you can afford it I feel this was A quality. Taste great, and helps me think of several different ways of doing tasks. Useful.

  • Jason - 10th Nov 2019

    Awesome addition

    As I mentioned with the Alpha GPC, I am so glad I purchased the two, together. This is the perfect combo for some extra fuel for the racetams in my stack. Again, awesome product and combo!

  • Chris - 7th Nov 2019

    Long half-life, quality product

    Clears up brain fog very well. Keep in mind that the half life of this chemical is ~60 hours, so it doesn't need to be taken every day.


    first disappointment with depot

    I had already used another cdp from a competitor and felt invincible, libido high thinking fast and willing, unfortunately did not feel the same with this cdp from nootropc depot, the effect was similar to the alpha gpc of another brand, calm thinking focus, but without libido and tired. ND Admin: It sounds like you got fake CDP choline from the other vendor. Libido increase is not an effect from citicoline. That sounds more like sulbutiamine. If you let us know the vendor, we'll buy some and run it through the lab. Ours is absolutely pure CDP choline dosed at the level stated on the bottle. We go through great lengths to ensure that.

  • Joshua Caron - 17th Aug 2019

    Not sure if it works for me!!

    Now keeping in mind, that I only used it once, and only took 100mg, I couldn;t expect to feel much but I didn;t feel any difference.

  • John - 12th Aug 2019


    There are a few supplements which I simply will not be without. Among those and at the top of my list is Citicoline. Citicoline can get expensive, so I really, really appreciate having a reliable supplier of high quality Citicoline. You all there at ND rock! I haven't had to wait more than a couple days for delivery like clockwork. And the product is top notch, i'm speaking from decades of experience with ordering bulk supplements. Should anyone want to know what Citicoline does, it's very well studied..just search and you'll see. I like to go on PubMed to find information. Just be sure to look at the conflict of interest statement for any studies you find. PubMed is free and vast. It's a .gov, NIH/NCBI. Tons of info on Citicoline there. Keep up the good work Nootropics Depot!

  • Kevin L - 28th Jul 2019

    One of my favorites

    I take this with Alpha-GPC and they give me a nice little kick in energy and focus. After taking them for a few months now, I can say my productivity has definitely gone up.

  • Kevin L - 16th May 2019

    Magic motivation powder

    I just take this along with ALCAR and Alpha GPC and I feel so motivated. I've never been more productive.

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