About Injuv Softgels

Injuv is a proprietary, low molecular weight hyaluronic acid complex engineered for high oral bioavailability and clinically shown to support skin moisture content. Unlike traditional hyaluronic acid supplements that are too large for intestinal absorption, Injuv's specialized enzyme-cleaving process reduces the molecular weight to 1,500-5,000 Daltons while preserving the compound's natural structure. The formulation works from the inside out to support skin health by replenishing hyaluronic acid levels that naturally decline with age.

Our Injuv Story

We recognized a fundamental problem in the hyaluronic acid supplement market: nearly all oral formulations were being excreted without providing benefits because their molecular weight was too large for absorption. Traditional hyaluronic acid exists as a high molecular weight polymer that cannot pass through the intestinal barrier, rendering most supplements ineffective despite promising research on hyaluronic acid's role in skin hydration and joint health.

We sourced Injuv, a clinically validated hyaluronic acid complex that uses proprietary enzyme-cleaving technology to dramatically reduce molecular size without altering the chemical structure. This breakthrough allows the hyaluronic acid to be absorbed through epithelial cells and delivered to target tissues, particularly the skin where nearly 50% of the body's hyaluronic acid naturally resides. The result is a supplement backed by human clinical trials showing statistically significant improvements in skin moisture content compared to both baseline and placebo.

Benefits

• Supports Skin Health: Injuv supports healthy transepidermal moisture balance to promote skin appearance and acts like an internal supporter of natural skin cell turnover to support fresh-looking skin.
• Supports Joint Health: Hyaluronic acid provides cushioning and lubrication within joints by maintaining the gel-like consistency of synovial fluid, which helps reduce friction and supports comfortable movement.
• Provides Antioxidant Support: The low molecular weight formula helps maintain cellular integrity by supporting the body's natural defenses against environmental stressors and free radical activity.
• Supports a Healthy Inflammatory Response: Studies suggest that oral hyaluronic acid helps maintain a healthy inflammatory response, particularly in joints and other tissues where hyaluronic acid is naturally concentrated.

Injuv also supports the natural life cycle of skin cells to promote their longevity while supporting nutrient flow to the epidermis and waste removal from it, creating an optimal environment for healthy cell maintenance and repair that supports even skin tone from within.

Quality and Standardization

• Proprietary Enzyme Processing: Our Injuv is manufactured using specialized enzyme-cleaving techniques that reduce molecular weight to 1,500-5,000 Daltons without altering the chemical structure, ensuring optimal bioavailability through the intestinal tract.
• Standardized to 9% Hyaluronic Acid: Each softgel contains precisely standardized hyaluronic acid content verified through size exclusion high-performance liquid chromatography (HPLC) for consistent potency and purity.
• Natural Source Material: Injuv is derived from rooster combs, a natural source that has been safely utilized for collagen supplements and hyaluronic acid extraction for over two decades in the supplement industry.
• Third-Party Verified Absorption: Laboratory testing using established animal models confirms that our low molecular weight hyaluronic acid is successfully absorbed and delivered to target tissues, including skin and joints.
• Clinical Research Validation: Human trials demonstrate statistically significant improvements in skin moisture content compared to baseline measurements and placebo groups, supporting the efficacy of our specialized formulation approach.

Mechanism of Action

• Molecular Weight Reduction: Injuv's enzyme-cleaving process breaks down hyaluronic acid to 1,500-5,000 Daltons, enabling absorption through intestinal epithelial cells where larger molecules would be rejected by the digestive system.
• Extracellular Matrix Integration: Once absorbed, hyaluronic acid integrates into the gel-like extracellular matrix that surrounds skin cells, creating a hydrated foundation that supports cellular health and proper nutrient transport.
• Water Retention Capacity: Each hyaluronic acid molecule can hold up to 1,000 times its weight in water, forming a moisture reservoir within skin tissues that maintains hydration levels even as environmental factors promote water loss.
• Epidermal Barrier Support: Hyaluronic acid supports the skin's protective barrier by filling intercellular spaces, helping maintain optimal moisture retention in the outermost skin layers.
• Tissue Delivery Pathway: Research demonstrates that orally administered low molecular weight hyaluronic acid reaches target tissues through systemic circulation, with cell regeneration studies confirming its arrival at skin sites where it supports moisturizing effects.

Overview of the Science

A randomized, double-blind, placebo-controlled clinical trial evaluated Injuv's effectiveness in 107 volunteers aged 30-50 over 30 days [1]. Participants receiving Injuv (140mg daily) demonstrated statistically significant increases in skin surface moisture content compared to both baseline measurements and placebo groups, as measured using standardized SHP88 probe technology. This human clinical evidence validates that orally administered low molecular weight hyaluronic acid successfully reaches and supports skin hydration from within.

Animal studies have further demonstrated Injuv's physiological activity through established skin rejuvenation models. Rats treated with oral Injuv exhibited significant skin health promoting characteristics compared to placebo controls, confirming that the absorbed hyaluronic acid reaches target tissues effectively. Additionally, research in mice showed that oral administration of Injuv at 3000mg/kg significantly supported healthy healing processes within just three days, highlighting its rapid bioactive effects. The consistent findings across both human and animal models provide robust evidence for Injuv's ability to deliver meaningful benefits through cellular health enhancement mechanisms.

[1] Rayess HM, Svinarich DM, Katsanis E. Plast Reconstr Surg. 2014;134(6):1224-1234.

Ingredients

Hyaluronic Acid (HA):

• 6.3mg from 70mg INJUV®
• Delivered in convenient softgel format
• Bioactive form for optimal absorption

The INJUV® hyaluronic acid in these softgels represents a specialized form that has been specifically processed for oral bioavailability. Unlike standard hyaluronic acid supplements that may have poor absorption due to molecular size, INJUV® utilizes a proprietary processing method that helps support the body's natural ability to utilize this important compound. This carefully controlled extraction and processing ensures consistent potency and quality in every softgel.