KSM-66 Ashwagandha Extract Powder

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  • KSM-66 Ashwagandha Extract Powder
  • KSM-66 Ashwagandha Extract Powder
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Active Ingredient:
KSM-66 Ashwagandha Extract (Withania somnifera)
5% Withanolides
Extract Type:
Full Spectrum Extract
Item Type:
Quantity Per Bottle:
30 Grams or 60 Grams
Servings Per Bottle:
100 Servings or 200 Servings
Suggested Use:
As a dietary supplement, take 300mg of KSM-66 Ashwagandha Extract 1-2 times daily
Contains Milk Allergens
Can affect thyroid function. Please speak to your doctor if you have a history of thyroid issues.
Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.
Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases. These statements have not been evaluated by the Food and Drug Administration.
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Buy KSM 66 Ashwagandha Powder

What is KSM-66 Ashwagandha Powder?

Ashwagandha, also known as Withania somnifera, has been a widely used and studied Ayurvedic herb for centuries, mainly for its potential effectiveness in supporting healthy stress levels. KSM-66, created by Ixoreal Biomed, is an easy-to-use Ashwagandha powder that can be added to capsules or taken with food and drink.

How is KSM-66 Ashwagandha Powder Made?

There are many Ashwagandha powder options on the market, but none quite compares to KSM-66. Committed to quality and safety, Ixoreal Biomed invested over 14 years of research and development in the creation of KSM-66. Made strictly from the roots (no leaves) of the plant for maximum clinical effectiveness, KSM-66 is acquired through a unique extraction process based on “Green Chemistry” principles, which do not make use of alcohol or synthetic solvents.

KSM-66 Ashwagandha Benefits

KSM-66 Ashwagandha benefits the body and mind in multiple ways, as shown through clinical trials and research studies. In fact, KSM-66 is the most extensively studied Ashwagandha extract on the market.

The bioactive constituents (compounds) of the Ashwagandha herb that are widely studied and lend to its positive effect on humans include notable alkaloids and over 35 withanolides. KSM-66 may reduce cortisol levels (the stress hormone) as well as the immunosuppressive effect that stress has on the body. One study showed a significant (nearly 28%) reduction in stress and serum cortisol levels. This is why KSM-66 is recommended for those who need help managing stress. This relaxing effect may also be helpful for sleep.

Besides managing stress, studies have shown KSM-66 to be a helpful aid in the following areas:

  • Cognition and memory* - One study showed improvement in executive function and attention, two key areas of the Wechsler Memory Scale.
  • Energy and stamina* - One study showed that Ashwagandha led to improvement in cardiorespiratory endurance and self-assessment scores for healthy athletes.
  • Weight management and well-being* - Increased levels of cortisol can signal your body to hold on to excess fat. Reducing cortisol levels not only helps stress but also weight loss and general feelings of well-being, according to one study.
  • Muscle strength, size, and recovery* - Ashwagandha has been shown to help healthy, active adults improve max resistance load and muscle recovery.
  • Testosterone levels in men* - One study found the herb to improve semen volume, sperm concentration and motility, serum luteinizing hormone (LH), and testosterone levels.
  • Libido in women* - One study reported improvements in desire, arousal, and satisfaction for women using Ashwagandha.

Why Buy KSM-66 Ashwagandha Powder?

Apart from the benefits we’ve discussed, there are several reasons to buy KSM-66 Ashwagandha.

  1. High-concentration, full-spectrum extract: 14 years of research and development paid off. Only Ixoreal has managed to refine an extraction process that maintains the natural balance of the constituents in the herb. Through “Green Chemistry” processing, Ixoreal’s science team found a way to holistically process Ashwagandha to preserve efficacy of active constituents in their natural proportions, including withanine, somniferine, tropine, steroidal lactones, and withanolides.
  2. A safer root-only extract; not made from leaves: Traditional Ayurvedic texts as well as the standard pharmacopoeias of India, Britain, and the U.S. describe solely the root for use. Many other manufacturers include extracts of the leaves, but there is no data supporting the efficacy or safety of such practices. Extracts that include the leaves can gain a higher percentage of overall withanolides, but this comes at the cost of increasing the amount of withaferin A, an undesirable cytotoxic withanolide. KSM-66 is the highest percentage available in root-only Ashwagandha extract at 5% concentration, and the amount of withaferin A found in this extract is negligible and, most importantly, very safe.
  3. Most extensive studies and research: Ixoreal leads the industry in performing clinical trials and research to investigate effectiveness of Ashwagandha in humans, collaborating with major research and academic institutions. All Ixoreal studies are randomized, double-blind, and placebo-controlled.
  4. Efficient pricing for highest-quality product on the market: Ixoreal uses cost-efficient business practices to pass savings on to customers, as it’s the only Ashwagandha manufacturer on the globe that manages its own farms, production facilities, laboratories and research center.
  5. Certifications you can trust: KSM-66 has attained more than a dozen trusted certifications for product quality and business practices. KSM-66 is 100% USDA Organic, Non-GMO Project verified, Certified Gluten-Free, JK Kosher, and more, as well as being GRAS-affirmed by the FDA. In line with WHO-cGMP and US-FDA, KSM-66 is manufactured in an ISO 9001:2008- and GMP-certified, state-of-the-art cleanroom facility. Additionally, KSM-66 is vegetarian and shelf-stable.
  6. Superior taste: Ixoreal’s unique extraction process preserves the compounds and lends itself to a neutral taste in foods and beverages. Other manufacturing processes, including hydroalcoholic, lead to a bitter taste.
  7. Award-winning product: KSM-66 has earned multiple awards.
  • Herbal Industry Leader 2016” by Society for Ethnopharmacology
  • Product Innovation in Botanicals 2014” by Frost and Sullivan
  •  Best Botanical Ingredient 2013” at Engredea/Natural Products Expo West
  •  Innovative Ingredient of the Year 2012” at Panacea

Always discuss the addition of nootropics and supplements with your doctor or another trusted healthcare professional, and stay informed about how a product might affect your unique body chemistry--everyone is different.


 As a dietary supplement, take 300mg of KSM-66 Ashwagandha Extract 1-2 times daily.

Learn more about Ashwagandha Extracts

Want to learn more about Sensoril, KSM-66 and general information about Ashwagandha extracts? Check out our ashwagandha blog hereYou can also gain more insight by reading the KSM-66 Ashwagandha reviews and experiences below. 

You may also like KSM-66 Ashwagandha Extract Capsules.

*Contains Milk Allergens

*Can affect thyroid function. Please speak to your doctor if you have a history of thyroid issues.

Attention: This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.


37 Reviews

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  • W.K. - 12th Aug 2017

    A safer root-only extract; not made from leaves

    The pursuit of health should not come at the cost of it. Reasonably priced for one of the highest quality product on the market.

  • Unknown - 15th Jun 2017


    Subtle and good taste

37 Reviews

  • W.K. - 12th Aug 2017

    A safer root-only extract; not made from leaves

    The pursuit of health should not come at the cost of it. Reasonably priced for one of the highest quality product on the market.

  • Unknown - 15th Jun 2017


    Subtle and good taste

  • Unknown - 10th Jun 2017


    The best ashwaghanda I've tried. Very, very helpfull.

  • Adam Frank - 24th May 2017

    Overall Good Product but Room to Improve

    At first, I was surprised that there was dosing information on the label but no feasible method provided to reasonably or consistently guess what that amount looks like.
    When I went to dilute the product it water I was amazed at how hydrophobic it is - it does not easily mix with water but if you use warm/hot water this issue is resolved slightly. However, the hotter water created the concern of affecting potency.
    Ultimately, while I enjoyed using this product and probably took significantly more per serving than I initially intended to because of it - and absent of the very high shipping costs, the price is great - I have since purchased KSM-66 with capsule delivery.
    I definitely recommend KSM-66 to everyone but will suggest capsules to avoid some of the aforementioned minor setbacks.

  • ck - 17th Apr 2017

    my favorite

    Great stuff. Very noticeable. Love this stuff.

  • Unknown - 23rd Feb 2017

    A mild taste without bitterness

    I found this form of herb to be mild in taste, as opposed to bitter, which I thought it would be. Makes it easy and more desirable to take daily, plus I find this form to not be over stimulating, which is what I was looking for in this herb.

  • Stephannie Edwards - 12th Jan 2017

    my life in 360

    So bad it affects my everyday life. I am so happy to have discovered this product. I finally feel like a normal person! KSM-66 has many benefits, but relief is a use I can personally recommend this for. Truly amazing product!

  • Nick Chlebeck - 4th Jan 2017

    Works Great

    I get all of the positive effects of this KSM-66. I love it!

  • Unknown - 26th Dec 2016

    KSM-66 Ashwagadha and telomere extensions

    On credible advice I contracted in August with Life Length of Spain through its US affiliate lab Age Diagnostic Labs (ADL) to measure my telomeres . According to ADL through Life Length, I was pleased that as a 72 year old, I have telomeres of a 70 year old. My plan is to have my telomeres measured again next August and hope to learn that the KSM-66 Ashwagandha after more than six months of consumption will have positively increased the difference between my physical age and my chronological age. Till then I can report that once I was able to find ways to consume the KSM-66 powder with its bitter taste masked, it is a manageable supplement to add to my daily regimen. Resurvey me next September.

  • Unknown - 27th Nov 2016

    Still taking, not sure yet.

    I am taking this now, haven't really done it regularly. I cleared it with my Psychiatrist who told me it would not cause a problem with my Zoloft. As time goes on I will see how effective it is. I believe I sleep better on it.

  • Nathan - 10th Oct 2016


    I used to need 10-12h of sleep to feel even somewhat functional. With KSM 66 I need about 6-7h and feel much more energized than I ever did! This gives me about 5h more time each day!!! I currently take 3 doses of 250mg per day and on a 3rd day it feels even better than on the first one.

    As for someone who has had long time problems that interfere with sleep, this is a godsend. It doesn't really make me sleepy but instead relaxes me enough so I release my thoughts when I choose to. When I do sleep, I am deeply asleep unlike in the past when I'd wake up multiple times each night.

  • Unknown - 29th Sep 2016

    Subtle, Yet Amazing

    I tried some regular ashwagandha before from another company and noticed pleasing effects, so I decided to try KSM-66. It's 3.5x more potent than the regular stuff I was using before, and it's simply amazing. I should note that it does take time for the best effects to build up, roughly a week.

    My wife and I take it every night before bed and we've seen noticeable improvements in our ability to fall asleep and stay sleep. It also gives me incredibly vivid dreams, usually adventurous, too.

    It also helps to stay calm throughout the day.

    We could take this 2-3 times per day, maybe more, but we get great effects from taking ~300 mg once nightly. Would recommend!

  • Cory - 24th Aug 2016

    Finally! I can take Ashwagandha!

    I've never been able to use Ashwagandha (like Sensoril or other types), as badly as I wanted to, because it would give me brain fog and make me feel very heavy and lethargic for hours afterward. I bought KSM-66 and had it for about 3 weeks before I got brave enough to test it, not willing to risk voluntarily ruining a good day.

    I finally decided to give it a shot, swallowed the powder, and braced for a crappy result, but it didn't come. I had none of the bad effects I've experienced in the past! I've only been taking it for about a week, so I don't want to make a judgement regarding its effects yet, but I wanted to make this review for those who've had negative experiences with Sensoril, etc., so you can consider giving this one a try.

  • John - 17th Aug 2016

    So far, so good.

    I have to give this more time, as I have forgotten to use it too many times. It seems to help provide a calmness, but I think there's more good things yet to come and I will revise this review as time passes. Very happy with the prices, especially since the quality of all the Depot's products appear excellent, and Paul is always around for advice and information.

  • jeremie - 6th Aug 2016

    Great product

    Very good quality. I love this product and the price is good.

  • Vishwa - 30th Apr 2016

    Delivered what it promised

    1. Increased Energy
    2. Impressed with the quality of Sleep
    3. Increased recovery after weight training sessions

    Highly potent! Not to play around with the dosages, start with 250 mg and increase gradually until you get your sweet spot on dosage. The more is not better.

    250mg in the morning (caused drowsiness) and 250mg in night (better sleep quality). Hence reduced to one dosage of 350 to 400 mg before bed. Works great for me!

    Advisable to give a break of 2 to 3 weeks after 3 months course.

    Highly satisfied with this patented form of Ashwangandha.

  • Phil - 23rd Jan 2016

    This is the Ashwagandha extract we have all been waiting for!!!

    This products puts other "standardized" extracts to shame!

    -First, it's 100% organic and uses ONLY the roots. Other popular standardized extracts use both root and leaves which spikes up the withanolide percentage, but this is not always desired.

    -KSM-66 makes sure to remove the cytotoxin Withanolide A. Other extracts don't even recognize that as a toxin!

    -KSM-66 has the full constituents of the root in it's naturally balanced proportions! This means getting beneficial amino acids and more ALONG with the sought-after withanolides.

    I've been taking this the past three days, and I feel absolutely amazing! Stronger, sharper, more creative, it's all great! It also tastes great, too (for extracts at least)!

    I'm so glad that Nootropics Depot has decided to carry this extract, especially when it already has two other ashwagandha products. This is the one you want, people, and it's a little cheaper! Please keep this in stock, ND!