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100% Vegan Lactose Free Gluten Free
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100% Vegan Lactose Free Gluten Free

Magnolia Bark Extract Tablets

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What is Magnolia Bark Extract?

Magnolia Bark, also known as Magnolia Officinalis, is a natural compound used in traditional Chinese practices and known for its ability to support healthy sleep habits and its relaxation properties. Magnolia Bark is a plant from the Magnolia species of plants that share similar compounds. Two of the compounds, Magnolol and Honokiol are the two primary active ingredients found in the bark. Honokiol and Magnolol are two biphenolic structural isomers called neolignans. They were first found in plants in the Magnolia family and historically used to support stress and respiratory health.

Magnolia Bark Benefits and Uses

    • May help support healthy cellular function*
    • May help promote feelings of well being*
    • May help support healthy stress levels*
    • May help promote healthy sleeping habits*

Magnolia Bark for Sleep

In 1983, tests on mice were conducted to see how they would respond to Magnolia Bark extract. Magnolia Bark’s benefits for sleep were first documented in these studies when researchers noticed calm and relaxed behavior among the mice. Further studies performed on rats found regulated serotonin release after the rats were injected with Magnolol. As a result, metabolic rate and colonic temperature were notably reduced. Research determined that Magnolia Bark extract seems to interact with the serotonin transporter but so far has not discovered how it interacts with the serotonin transporter. However, it is able to regulate serotonin release from neurons.

The neolignans found in Magnolia Bark extract (Honokiol and Magnolol) have been found to interact with GABAA receptors in both in vitro and in vivo studies. 

Relaxation effects were noted with Magnolol in isolation and seems to promote healthy sleep patterns when taken orally. In addition, GABAA agonists will augment the effects. Clinical studies have found that the neolignans (Magnolol and Honokiol) in Magnolia bark seem to have a positive impact on modulating muscarinic acetylcholine receptors in a similar fashion to how they impact GABAA receptors.

The neolignans in Magnolia Bark (Magnolol and Honokiol) seem to increase the binding affinity of muscarine to the muscarinic acetylcholine receptors.* This is due to its ability to allosterically modify low binding receptors to a higher binding capacity and therefore causing a larger amount of overall binding. Magnolol and Honokiol both increased binding in rat cerebella by 64% and 71% respectively and 2.8 and 3.2-fold respectively in rat forebrains.

Magnolia Bark Extract Standardization

This Magnolia Bark Extract is standardized to Magnolol + Honokiol minimum content 80% by UPLC

Magnolia Bark Recommended Dosage

As a dietary supplement, take one 200mg Magnolia Bark Extract tablet once daily. 

Magnolia Bark Extract Reviews

To gain more insight, read the Magnolia Bark Extract tablets reviews and experiences below.

Where Can I Buy Magnolia Bark Extract?

Nootropics Depot offers 30ct. and 90ct. jars of high-quality Magnolia Bark extract tablets. Nootropics Depot’s Magnolia Bark has been lab-tested and verified for both product purity and identity.

  *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Reviews

  • 5
    Doctor told me to quit Xanax cold turkey- I used this!

    Posted by Natalie Boyette on 28th Aug 2024

    Back in 2021, the doctor told me to quit Xanax cold turkey, no need to say I almost died! It was the hardest thing I have ever gone through! I tried different supplements to help me! For the first two years, I had a hard time finding something that would help me until I found this supplement. This brand is also the best quality! I totally recommend it.

  • 3
    I don’t like bad reviews but…

    Posted by DW on 13th Apr 2023

    I don’t like bad reviews but… this has given me hives. Took awhile to Isolate but I’m 98% sure this is it. I will give it another try when I stop truck driving and can get back into a better health routine. This is the second batch I bought. The first one didn’t do it to me I don’t think.

  • 5
    Great, mild, helps me stay asleep.

    Posted by N E on 7th Jan 2023

    I've previously individually taken valerian root, glycine, and a few other substances all to try and help out my sleep issues. My main issue is that no matter when I go to bed, I pretty much always wake up at 8 or 9 AM, and tend to be a light sleeper to noise and thermal changes while asleep - giving me a lot of energy and irritation issues when my sleep is almost always interrupted. This magnolia bark has been a great, mild way that I notice helps me stay asleep better and fall asleep faster, without sedative effects. Glycine has previously worked well for me in in this way as well, but I was getting tired of taking three giant pills before bed, and my stomach wasn't tolerating all that powder well. These tablets are much smaller and easier to take before bed, with similar effect. Thanks for stocking this!

  • 4
    Magnolia Bark

    Posted by Steve Fox on 23rd Jul 2022

    A great product - part of my sleeping stack. Do yourself a favor and look into intermediate and advanced stacks with this product.

  • 5
    Magnolia Bark Extract

    Posted by Kathy on 2nd May 2022

    I use this product for inflammation I take one A-day most generally I have post polio syndrome and it's amazing how much it helps the pain and it has so many other redeeming qualities Google it and read about everything it's harmless best I can tell and really does help!!

  • 4
    Scored tablets for the win

    Posted by Feeback McBackfeed on 9th Apr 2022

    Magnolia is a little strong for me, so having the scored tablets improves it usefulness. Improves sleep onset, but seems to keep me in a lighter REM state too long. Might be good if you want those dreams.

  • 5
    Magnolia bark-if I had to choose one product to buy at ND

    Posted by Deron on 4th Apr 2022

    It would be this. It is just solid for so many things if you will in your body and brain. It affects the activity of both serotonin and dopamine. And I also take Ginger and never have any sort of mood issues. In addition to reducing cortisol, helping with slumber. It seems to improve a variety of mood state parameters anecdotally, and I'm an ADHD PI and I know it helps subtlety with my attention issues, however you can feel it. And it's really makes a difference with my oral health come including bacteria build up, and my gums never bleed anymore after supplementing magnolia bark. How do you make sure I cycle it, maybe two weeks on 2 weeks off kind of thing. And finally knowing it helps somewhat with brain information, this herb does a lot of good things for one's body. Thanks ND for providing such a high quality version!

  • 5
    Balanced & Calming

    Posted by William on 18th Feb 2022

    Don't look to this to knock you out, however the first few times I took it I noticed I was a bit drowsy. Now that I take it regularly it's definitely not even noticeable, I take this in the evenings with Magtein & zinc & I do notice it takes an edge off though...I'm less apt to worry about work etc. Exactly what I wanted. Question for the ND Admin, can I take 2 pills daily? I've read that it's safe to take up to 500mg daily and I'm 6' 1" 200lbs. Any input is appreciated, thanks!

  • 2
    MAGNOLIA BARK EXTRACT TABLETS | 200MG |

    Posted by Morgan on 7th Feb 2022

    I am taking it at night for sleep. Routinely I sleep about 4-5 hours with periods of wakefulness lasting a half hour to two hours. It takes a long time to fall asleep. I won't buy these again awhen I run out UNLESS my sleep patterns get worse,, then I'll believe they were helping a bit and may try them again.

  • 5
    Love it!

    Posted by Daniel Cutts on 7th Oct 2021

    I take it at night to help me sleep and it sure does! ND is the best!

  • 5
    Best product available for sleep support

    Posted by Daniel on 12th Jul 2021

    I've tried a variety of products from both ND and other retailers for sleep support. This has been the most effective for me, even compared to Lemon Balm. It seems to increase the quality of my sleep more than anything. I do highly recommend this.

  • 5
    Magnolia Bark has become my favorite herb

    Posted by Deron on 24th Oct 2020

    ... this is a magic herb to me. It makes a noticeable difference with my diagnosed attention issues. And it goes without saying ND takes the now very popular game of nootropics to a level no other company touches in terms of testing. If they're unsure or are not 100% confident with their in-house testing due to a multitude of reasons, they send the nootropic or supplement to a third party testing facility/to ensure the product is perfect before releasing...for us, the consumer. This is easily the best magnolia bark on the market, as I'm able to sleep better, incur better clarity of mind, and have an overall calmness/well being throughout the day. And it continues to amaze me how quickly their products make it to my mailbox. Thanks ND!

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*Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.