About NADH w/ Chlorella Capsules
NADH with Chlorella combines the most direct NAD+ precursor with a natural stability blend for enhanced cellular health supplements delivery. NADH converts to NAD+ in a single oxidation step while simultaneously generating ATP, making it the most efficient way to boost both cellular energy and NAD+ levels. The chlorella and sodium ascorbate blend protects NADH stability for maximum potency.
Our NADH Story
We first began exploring NAD supplements after noticing a significant gap in the market. While NMN and Nicotinamide Riboside were delivering solid longevity benefits, many users weren't experiencing the pronounced energy effects they expected from NAD+ enhancement. We needed something that could deliver both the long-term NAD+ benefits and immediate energizing effects in one product.
Our research led us to NADH, the reduced form of NAD+ that sits at the heart of cellular ATP production. During beta testing, we immediately noticed how much more energizing NADH was compared to other NAD+ precursors. The reason became clear: NADH doesn't just convert to NAD+, it actively participates in the electron transport chain where ATP is generated. This dual mechanism delivers what we call "cellular rocket fuel."
We formulated our NADH with chlorella and vitamin C to address stability concerns and ensure consistent potency. This stability blend allows us to deliver the full energizing potential of NADH while maintaining the long-term cellular benefits that make NAD+ enhancement so valuable for healthy aging and metabolic function.
Benefits
- Boosts Cellular Energy: NADH directly fuels ATP production in your mitochondria through the electron transport chain, delivering energizing effects that beta-testers consistently noticed compared to other NAD+ precursors.
- Enhances Mental Energy: The rapid conversion of NADH to NAD+ supports cognitive function and mental clarity, with many users reporting more sustained mental Energy throughout the day compared to traditional stimulants.
- Supports Mitochondrial Health: Active transporters deliver NADH directly to mitochondria where it optimizes cellular respiration and helps maintain the efficiency of your cellular powerhouses as you age.
- Supports Healthy Aging: NADH helps counter the natural decline in NAD+ production that occurs with aging, supporting cellular repair mechanisms and maintaining optimal Metabolism function.
The chlorella provides additional stability and antioxidant protection for the NADH, while the sodium ascorbate (vitamin C) shields the compound from degradation. This stability blend ensures you receive the full potency of this cellular fuel while supporting your body's natural circadian rhythms and overall vitality.
Quality and Standardization
- NADH Purity: Our NADH is lab-tested and verified for both product purity and identity to ensure you receive the highest quality reduced NAD+ coenzyme.
- Stability Enhancement: We use chlorella as a natural chlorophyll source to improve NADH stability, combined with sodium ascorbate (vitamin C) for additional antioxidant protection.
- Mitochondrial Delivery: NADH utilizes active transporters that specifically deliver it to cellular mitochondria where ATP synthesis occurs, maximizing bioavailability and efficacy.
- Quality Sourcing: Our formulation focuses on maintaining the integrity of this delicate coenzyme through careful sourcing and specialized manufacturing processes to preserve its anti oxidative stress properties.
Mechanism of Action
- Mitochondrial Transport: NADH utilizes dedicated active transporters to reach mitochondria where ATP synthesis occurs, ensuring efficient delivery to the cellular powerhouses that generate energy.
- Electron Transport Chain Integration: NADH directly participates in complex I of the electron transport chain, where its oxidation drives proton pumping and creates the electrochemical gradient needed for ATP production.
- Dual Conversion Pathway: During ATP synthesis, NADH undergoes oxidation that simultaneously produces both cellular energy and NAD+, creating a metabolically efficient process that addresses both immediate energy needs and longevity support.
- Chlorella Stability Matrix: The chlorophyll compounds in chlorella form protective complexes with NADH that prevent degradation, while vitamin C provides additional antioxidant protection to maintain potency during storage and digestion.
Overview of the Science
Research indicates NADH supplementation may support energy production and reduce fatigue perception in certain populations [1][2][3]. Studies examining NADH effects on chronic fatigue syndrome have shown mixed results, with some trials reporting improvements in fatigue scores and quality of life measures when NADH is combined with other compounds like Coenzyme Q10 [2][3]. However, not all research has demonstrated cognitive benefits, with one controlled trial finding no evidence for cognitive improvement in dementia patients [4]. The energizing effects observed in clinical settings appear to be related to NADH's direct participation in mitochondrial ATP synthesis, where it serves as an electron donor in the respiratory chain.
Chlorella research has focused on its potential benefits for cardiovascular health and metabolic function [5][6][7]. Clinical trials have examined chlorella supplementation effects on lipid profiles, with one randomized controlled study reporting favorable changes in serum lipid and carotenoid levels in adults with mild hypercholesterolemia [6]. Additional research has investigated chlorella's role in supporting liver function, particularly in individuals with non-alcoholic fatty liver disease [7]. A recent crossover trial also evaluated chlorella's antioxidant potential, measuring its impact on oxidative stress markers in healthy subjects [8].
[1] Forsyth LM, Preuss HG, MacDowell AL, et al. Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome. Ann Allergy Asthma Immunol. 1999;82(2):185-91.
[2] Castro-Marrero J, Segundo MJ, Lacasa M, Martinez-Martinez A, Sentañes RS, Alegre-Martin J. Effect of dietary coenzyme Q10 plus NADH supplementation on fatigue perception and health-related quality of life in individuals with myalgic encephalomyelitis/chronic fatigue syndrome: a prospective, randomized, double-blind, placebo-controlled trial. Nutrients. 2021;13(8):2658.
[3] Alegre J, Cordero MD, Segundo MJ, et al. Does oral coenzyme Q10 plus NADH supplementation improve fatigue and biochemical parameters in chronic fatigue syndrome? Antioxid Redox Signal. 2015;23(10):679-85.
[4] Rainer M, Kraxberger E, Haushofer M, et al. No evidence for cognitive improvement from oral nicotinamide adenine dinucleotide (NADH) in dementia. J Neural Transm. 2000;107:1475-81.
[5] Merchant AT, Pitiphat W, Douglass CW, Crohin C, Joshipura K. A review of recent clinical trials of the nutritional supplement Chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis. Altern Ther Health Med. 2001;7(3):79-91.
[6] Ryu NH, Lim Y, Park JE, et al. Impact of daily Chlorella consumption on serum lipid and carotenoid profiles in mildly hypercholesterolemic adults: a double-blinded, randomized, placebo-controlled study. Nutr Metab Cardiovasc Dis. 2014;24(12):1330-6.
[7] Ebrahimi-Mameghani M, Aliashrafi S, Javadzadeh Y, AsghariJafarabadi M. The effect of Chlorella vulgaris supplementation on liver enzymes, serum glucose and lipid profile in patients with non-alcoholic fatty liver disease. Health Promot Perspect. 2014;4(1):107-15.
[8] Liu J, Wu Y, Ho CH, et al. Beneficial effect of Chlorella pyrenoidosa drink on healthy subjects: A randomized, placebo-controlled, double-blind, cross-over clinical trial. J Food Sci. 2021;86(5):1861-1870.
Ingredients
NADH w/ Chlorella:
- Chlorella spp. (broken cell) - 400mg
- Reduced Nicotinamide Adenine Dinucleotide (NADH) - 20mg
This formula pairs NADH with broken cell chlorella to enhance bioavailability and stability. Chlorella's protective matrix helps preserve NADH's delicate structure during digestion, while the broken cell processing ensures optimal nutrient absorption. The 20mg NADH dosage provides meaningful support for cellular energy production without the stability concerns often associated with standalone NADH supplements.