null Skip to main content

Poria Mushroom Extract Capsules

Organic whole fruiting body extract standardized to 55% beta-glucans for immune, digestive, respiratory, and cognitive support.

(7 Reviews) Write a Review

View All Reviews

Poria Mushroom Extract Capsules

Organic whole fruiting body extract standardized to 55% beta-glucans for immune, digestive, respiratory, and cognitive support.

(7 Reviews) Write a Review

View All Reviews

Available in multiple forms! Click Here for:
  • Pure Fruiting Body Extract
  • Standardized to 55% Beta-Glucans
  • Rich in Bioactive Pachymic Acid
  • Traditional Cognitive Support

3rd Party Lab Tested & Verified

See Why ND Poria Is The Best

Updated On: 05/23/2026

$19.99
Adding to cart… The item has been added

Benefits

When You'll Notice Effects

2-3 Weeks

  • Immune
  • Sleep
  • Stress
  • Oxidation

Why ND Poria Mushroom?

A premium Poria Extract with 55% Beta-Glucans minimum guaranteed
test

How To Take

Dose
Dose

500mg (One Capsule)

Timing
Timing

Flexible

How to Take
How to Take

With Or Without Food

Frequency
Frequency

1-2 Times Daily

Reddit Icon

Talk to thousands of customers just like you.

Join our community on Reddit to ask questions, share experiences, and get the unfiltered truth from long-term users. We believe in letting our customers speak for themselves, so you can hear the real story from people just like you.

Visit Our Subreddit
  • About Poria Mushroom Extract Capsules

    Poria mushroom extract delivers the bioactive compounds from Wolfiporia extensa's sclerotium, standardized to 55% beta-glucans for consistent potency. This traditional Chinese medicine staple supports cellular function, respiratory health, and cognitive performance through its rich concentration of triterpenes, pachymic acid, and polysaccharides.

    Our Poria Story

    Traditional Chinese practitioners have revered Poria cocos for thousands of years as one of their most versatile therapeutic mushrooms, but finding a high-quality, properly standardized extract proved challenging for modern supplement users. Most commercial Poria products lack standardization and proper identification, leaving consumers uncertain about what they're actually getting.

    We source certified organic whole fruiting bodies and developed a specialized extraction process that concentrates the mushroom's most bioactive compounds while preserving their natural ratios. Our extract guarantees a minimum 55% beta-glucan content through rigorous UPLC testing, ensuring you receive the same compounds that made Poria a cornerstone of traditional wellness practices. This standardization delivers consistent immune and cognitive support with every capsule.

    Benefits

    • Supports Healthy Immune Function: Poria's rich beta-glucan content and triterpenoids work together to promote robust immune system activity and cellular defense mechanisms.
    • Promotes Healthy Sleep Quality: Traditional Chinese practices valued Poria for its calming properties that help support relaxation and natural sleep cycles through gentle nervous system modulation.
    • Supports a Balanced Stress Response: The mushroom's adaptogenic compounds help the body maintain balanced cortisol levels and promote resilience during daily stressors.
    • Supports Antioxidant Activity: Pachymic acid and other triterpenoids in Poria provide antioxidant support that helps protect cells from oxidative stress and supports healthy aging processes.

    Poria also enhances digestive wellness and respiratory function, making it a comprehensive wellness ally. The mushroom's unique ability to support cerebral blood flow contributes to enhanced cognitive clarity and mental sharpness, particularly when combined with complementary herbs like Polygala Tenuifolia for brain health support.

    Quality and Standardization

    • Beta-Glucan Standardization: Our Poria mushroom extract is standardized to a minimum of 55% beta-glucans, ensuring consistent levels of these immune-supporting polysaccharides that contribute to the mushroom's traditional health benefits.
    • Whole Fruiting Body Extract: We use only the complete fruiting body of Wolfiporia extensa rather than mycelium-based products, providing the full spectrum of bioactive compounds including triterpenoids, pachymic acid, and amino acids found in traditional preparations.
    • Certified Organic Sourcing: Our Poria mushroom extract is certified organic, ensuring cultivation without synthetic pesticides, herbicides, or artificial additives while maintaining the integrity of this revered medicinal mushroom.
    • Third-Party Laboratory Testing: Each batch undergoes comprehensive testing for purity, potency, and identity verification at independent laboratories, with Certificate of Analysis (COA) documentation available to confirm our quality standards and ingredient specifications.

    Mechanism of Action

    • Beta-Glucan Activity: The 55% beta-glucan content in Poria activates immune cell receptors, particularly macrophages and dendritic cells, which recognize these polysaccharides as immune-stimulating compounds that help coordinate the body's natural defense responses.
    • Triterpenoid Pathways: Pachymic acid and other triterpenoids in Poria modulate cellular signaling pathways related to supporting a healthy inflammatory response, working through nuclear factor pathways to support balanced immune system activity.
    • Cerebral Blood Flow Enhancement: Poria's bioactive compounds support healthy circulation to brain tissue, promoting optimal oxygen and nutrient delivery that contributes to cognitive function and mental clarity.
    • Neurotransmitter Support: The mushroom's amino acid profile and triterpenoid compounds help maintain healthy levels of neurotransmitters like acetylcholine, supporting communication between brain cells and memory formation processes.

    Overview of the Science

    Research on Poria mushroom extract has revealed multiple bioactive mechanisms that contribute to its traditional health applications. Studies suggest that beta-glucans from Poria cocos support immune function by activating macrophages and enhancing natural killer cell activity [2]. The triterpenoid compounds, particularly pachymic acid, support healthy digestive function, with one study showing that Poria cocos extracts helped improve functional [...] by regulating brain-gut peptides and supporting gastrointestinal mucosa repair [4]. Additionally, research indicates that Poria supports cognitive health through multiple pathways, including benefits for memory formation and neuronal protection in preliminary animal studies [6].

    The polysaccharide fraction of Poria cocos has also been investigated for its support of antioxidant activity, with studies showing that carboxymethyl beta-glucan derivatives from the mushroom exhibit significant antioxidant activity [7]. This antioxidant support contributes to the mushroom's traditional use in supporting cellular health and overall vitality. Furthermore, preliminary research suggests that Poria's bioactive compounds work synergistically with other traditional Chinese herbs, particularly in formulations designed to support respiratory and longevity pathways, though more human clinical trials are needed to fully understand these mechanisms.

    [2] Akramiene D, Kondrotas A, Didziapetriene J, Kevelaitis E. Effects of beta-glucans on the immune system. Medicina (Kaunas). 2007;43(8):597-606.

    [4] Liu YT, Sun J, Xiong ZJ, et al. Extracts of Poria cocos improve functional [...] via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa. J Ethnopharmacol. 2022;281:114548.

    [6] Li YL, Li XH, Wong YS, Chen FS, Jiang Y, Wu H, Sun J. Poria cocos could ameliorate cognitive dysfunction in APP/PS1 mice by restoring imbalance of Aβ production and clearance and gut microbiota dysbiosis. Aging (Albany NY). 2021;13(2):1829-1846.

    [7] Wang Y, Zhang H, Li Y, et al. Carboxymethyl (1→3)-β-d-glucan sulfate exhibits antioxidant activity. Carbohydr Polym. 2014;101:231-236.

    Ingredients

    Wolfiporia extensa Extract (sclerotium):

    • Botanical name: Wolfiporia extensa
    • Extract source: Sclerotium (underground fungal mass)
    • Amount per serving: 500mg

    Our Poria extract is sourced specifically from the sclerotium, the dense underground storage organ where the mushroom concentrates its most bioactive compounds. This targeted extraction ensures you get the full spectrum of triterpenes and polysaccharides that make Poria such a valued ingredient in traditional wellness practices. The 500mg serving provides a substantial dose that aligns with traditional usage levels, delivering the comprehensive benefits this remarkable fungus has to offer.

  • Lab Testing Results / Certificate of Analysis (COA)

  • Frequently asked questions

    1. How does Nootropics Depot's Poria compare to Lion's Mane?

      Poria mushroom extract and Lion's Mane target different health areas - our Poria is standardized to 55% beta-glucans and focuses on immune support, sleep quality, and stress response, while Lion's Mane specializes in cognitive enhancement and nerve growth factor support. Poria offers broader adaptogenic benefits with its triterpenoids and pachymic acid, making it ideal for overall wellness and immune function. Lion's Mane is more targeted for brain health and cognitive performance.

    2. Can I stack Poria with Nootropics Depot's Reishi extract?

      Yes, Poria mushroom extract stacks well with our Reishi extract since both are adaptogenic mushrooms that support healthy stress response and sleep quality through complementary mechanisms. Poria provides beta-glucans and triterpenes for immune and cognitive support, while Reishi offers its own unique bioactive compounds for relaxation and overall wellness. Both can be taken together at their standard doses without timing restrictions since Poria is flexible with food and timing.

    3. Does ND's Poria work better than White Jelly Mushroom?

      Our Poria and White Jelly Mushroom serve different primary purposes, so "better" depends on your specific goals. Poria is standardized to 55% beta-glucans and focuses on immune function, stress response, and sleep quality, while White Jelly Mushroom targets skin hydration and cognitive support through hyaluronic acid content. Both are high-quality extracts, but they're designed for different health applications rather than being directly comparable.

    4. Can I combine Nootropics Depot's Poria with Pomella?

      Yes, Poria mushroom extract can be safely combined with Pomella pomegranate extract as they work through different pathways and complement each other well. Poria supports immune function and stress response through beta-glucans and triterpenes, while Pomella provides cardiovascular and cognitive benefits through punicalagins. Both can be taken with or without food according to your preference.

    5. How does ND standardize their Poria to 55% beta-glucans?

      Our Poria mushroom extract is standardized through careful extraction and testing processes that concentrate the bioactive beta-glucan compounds from the Wolfiporia extensa sclerotium. We use analytical methods to verify that each batch contains exactly 55% beta-glucans, ensuring consistent potency and therapeutic value. This standardization process isolates the most beneficial compounds while maintaining the mushroom's natural triterpene and polysaccharide profile.

    6. Is Nootropics Depot's Poria better than Cordyceps for cognition?

      Both Poria and Cordyceps offer cognitive benefits through different mechanisms, making them complementary rather than directly comparable. Our Poria mushroom extract supports cognitive function through its 55% beta-glucan content and adaptogenic stress response benefits, while Cordyceps primarily enhances cognition through improved cellular energy and oxygen utilization. For comprehensive cognitive support, many customers find value in rotating between both or incorporating them into different parts of their supplement routine.

    7. Can I take ND's Poria with EpiCor and Maitake?

      Yes, our Poria Mushroom Extract can be taken alongside EpiCor and Maitake as they work through complementary immune support pathways. Poria provides beta-glucans and triterpenoids that support cellular defense mechanisms, while these combinations can offer synergistic immune system benefits. We recommend spacing them throughout the day if taking multiple immune supplements to optimize absorption.

    8. Why does Nootropics Depot use whole fruiting bodies?

      We use whole fruiting body extract because it contains the full spectrum of bioactive compounds found in Poria mushroom, including beta-glucans, triterpenes, and pachymic acid in their natural ratios. Our Poria extract is standardized to 55% beta-glucans while preserving the complete profile of polysaccharides and triterpenoids that traditional Chinese medicine has valued for thousands of years. This whole fruiting body approach ensures you get the synergistic benefits of all the mushroom's active compounds working together.

Trust Through Transparency

Your health matters, which is why we only use the best 3rd party ISO accredited labs and cGMP certified and FDA registered facilities right here in the USA

Learn more

Frequently Bought Together

Please choose options for all selected products

Poria Mushroom Extract Capsules

Poria Mushroom Extract Capsules

$19.99