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100% Vegan Lactose Free Gluten Free
See Dietary Information
100% Vegan Lactose Free Gluten Free

Agmatine Sulfate Capsules

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label-lactose-free:
true
label-gluten-free:
true
label-gmo-free:
false
label-vegan:
true
label-vegetarian:
true
info-dose:
250mg (One Capsule)
info-dose-timing:
Flexible
info-dose-frequency:
Once or Twice Per Day
info-how-to-take:
With Or Without Food
benefits-effect-days:
1-2 Weeks (With Acute Effects)
Benefits:
Cognition
Benefits:
Pain Support
Benefits:
Neuroprotection
Benefits:
Oxidation
product-summary:
  • Supports Cognitive Function
  • Supports Pain Management
  • Promotes Neuroprotection
  • Prevent Oxidative Stress-Related Issues
page-fact-checked:
false
research-snapshot-summary:
Agmatine sulfate, derived from L-arginine, is involved in protein synthesis. It may support cognitive function, aid in pain management, offer neuroprotective effects, and help prevent oxidative stress by reducing inflammation and protecting mitochond
Dietary Restrictions:
Lactose Free
Dietary Restrictions:
Gluten Free
Dietary Restrictions:
Vegan
Dietary Restrictions:
Vegetarian
Type:
Capsules
Type:
Amino Acids
Type:
Nootropics
Type:
Pre-Workout
disable-paypal:
true
lab-testing:
AGSCS1011824 | AGSCS1011824_240ct_signed.pdf
lab-testing:
AGSCS1032124 | AGSCS1032124_60ct_signed.pdf
lab-testing:
AGSCS1041624 | AGSCS1041624_120ct_signed.pdf
lab-testing:
AGSCS1083123 | AGSCS1083123_60ct_signed.pdf
lab-testing:
AGSCS1092923A | AGSCS1092923A_240ct_signed.pdf
lab-testing:
AGSCS1102523A | AGSCS1102523A_120ct_signed.pdf
lab-testing:
AGSCS1110723 | AGSCS1110723_240ct_signed.pdf
lab-testing:
AGSCS1112223A | AGSCS1112223A_120ct_signed.pdf
lab-testing:
AGSCS2071823 | AGSCS2071823_240ct_signed.pdf
$14.99
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Product Usage

Dose Dose

250mg (One Capsule)

Dose Timing Dose Timing

Flexible

How to Take How to Take

With Or Without Food

Dose Frequency Dose Frequency

Once or Twice Per Day

Summary

Agmatine sulfate, derived from L-arginine, is involved in protein synthesis. It may support cognitive function, aid in pain management, offer neuroprotective effects, and help prevent oxidative stress by reducing inflammation and protecting mitochond

Benefits

Time to notice full effects: 1-2 Weeks (With Acute Effects)

  • Cognition Cognition
  • Pain Support Pain Support
  • Neuroprotection Neuroprotection
  • Oxidation Oxidation

ATTENTION EUROPEAN CUSTOMERS: Some EU countries consider agmatine a novel food ingredient, and may not allow it through customs. Please look up your country's specific regulations before purchasing.

What is Agmatine Sulfate?

Agmatine sulfate is a common amino acid derived from L-arginine that’s involved in protein synthesis. When L-arginine undergoes decarboxylation, a process that results in the removal of a carboxylic acid group, it converts into agmatine sulfate. Agmatine sulfate is stored in neurons within the brain and gets released when those neurons are activated.

Agmatine sulfate is regarded as a neuromodulator and neurotransmitter which may explain some of the Agmatine sulfate nootropic benefits some people tend to experience. As a nootropic, Agmatine sulfate offers a diverse profile of potential Agmatine sulfate benefits for brain health and function as well as overall fitness.

Agmatine Sulfate Benefits and Uses

    • May help promote positive emotional outlook*
    • May help support restful sleep*
    • May help promote immune system function*
    • May help promote strength and endurance*
    • May help support gastric motility and digestion*
    • May help support cognitive function*
    • May help promote cardiovascular function*

Agmatine Sulfate Bodybuilding and Nootropic use

Agmatine benefits may involve an array of organs and bodily systems to help promote overall health. Agmatine sulfate’s interaction with NMDA and Nitric oxide receptors have been shown to promote several elements of cognitive function and brain health. In particular, these results focused heavily on memory and learning abilities. Research on Agmatine benefits on animals uncovered Agmatine sulfate’s ability to support healthy oxidation levels. It is believed that this may be a result of Agmatine’s capacity to limit glutamate activity. High glutamate activity can potentially induce over-excitation in the brain. This over-excitation is known as excitotoxicity. Excitotoxicity can cause nerve cells to degrade due to being overactivated. 

As far as how this translates to Agmatine sulfate nootropic effects, Agmatine seems to interact with a few neurotransmitter pathways and systems. When it comes to glutamate receptors, studies found that Agmatine appears to act strongly on these receptors and pathways. Research has found that Agmatine levels tend to increase in some regions of the brain when engaged in a learning process. Agmatine even appeared to exert some influence in memory formation in these areas. Taking an Agmatine supplement may help support memory formation events which may increase overall cognitive function with an emphasis on learning and memory.*

Agmatine has also forged a reputation in the bodybuilding community for its ability to create massive muscle pumps via its Nitric oxide regulation. Nitric oxide is a compound that’s naturally produced in our bodies and plays an important role in cell signaling and communication throughout the entire system. Anecdotal reports suggest that this enhanced connection may also promote feelings of well being. Agmatine sulfate is highly utilized as a main ingredient in various pre-workout formulas and “pump” supplements. In fact, it’s very common among bodybuilders to pair a pre-workout with agmatine sulfate. Some athletes swear by the agmatine sulfate bodybuilding benefits. As if boosting Nitric oxide levels and promoting cognitive function weren’t enough agmatine benefits for you, Agmatine sulfate also appears to support blood flow by behaving as a calcium antagonist. Research has found that this interaction may help widen and soothe blood vessels which in turn may support overall cardiovascular function. What’s even better, is that Agmatine may help create lean muscle mass and may even promote muscle definition. This makes Agmatine sulfate one of the best muscle pump supplements out there!

How Agmatine Sulfate May Promote Cognitive Function*

Agmatine sulfate also appears to interact with NMDA glutamate receptors. When these receptors get activated, they allow ions with a positive charge to pass through cell membranes. NMDA receptors are also one of the major glutamate receptors involved in regulating synaptic plasticity and memory functions. Synaptic plasticity is important for the ability of signals between nerves to strengthen or weaken over time. A healthy level of synaptic plasticity means signals are more effectively communicated between neurons.

How to take Agmatine Sulfate and Agmatine Sulfate Dosage

As a dietary supplement, take one 250mg Agmatine Sulfate capsule 1-2 times daily.

Agmatine Sulfate Reviews

To gain more insight, read the Agmatine sulfate reviews and experiences below.

Where to Buy Agmatine Sulfate Capsules

Nootropics Depot offers 60ct. or 120ct. jars of high quality Agmatine Sulfate capsules. Nootropics Depot's Agmatine Sulfate has been lab tested for product purity and identity. 

You may also be interested in agmatine sulfate powder.

 *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Reviews

  • 5
    Best available

    Posted by JP on 23rd May 2024

    I take this for nerve pain, relaxation and sleep. The bonus is it seems to make RX medication more effective. That's worth it when you're not wanting to preserve the overall effectiveness of RX by taking less of it or less frequently.

  • 5
    Saved my life

    Posted by Austin on 18th Apr 2024

    Had heart problems one day. Immediately remembered I bought these. Thankfully it was there

  • 5
    Big difference!

    Posted by Spencer Ricketts on 1st Apr 2024

    Agmatine Sulfate is by far the most helpful supplement I've tried so far. It gave me an upset stomach the first few times I took it at the recommended dose. But my stomach got used to it, & it didn't take long for me to notice the effects. This stuff works FAST, like within an hour or two of taking it. Helps me focus far more than anything else, keeps my mood smooth & even-keel. Almost complete cessation of anxiety, thought spirals, etc... The other cool thing is the synergistic reaction with cannabis, I believe this to be due to the NMDA receptor activity, as well as a possible upregulation of the endocannabinoid receptor sites. I initially bought this stuff to help me quit vaping, and it seems to help although not much at 250 mg. I'm going to experiment with higher doses and see what happens, but I'll take that slowly and cautiously. This is some powerful stuff afterall. All in all, I offer a big thanks to ND for providing such high-quality supplements. Keep doing what you guys do!

  • 5
    This works

    Posted by Gabriel on 23rd May 2023

    This helps me with pain and lifts my mood for a few hours , also gives a slight cognitive boost, I have been taking 500 mg daily on an empty stomach, it seems to be lowering glutamate, and inflammation, I will continue taking this.

  • 5
    The most effective mood booster I've tried yet!

    Posted by paul c. on 17th Apr 2023

    I've tried all sorts of medications for attention issues and low mood for a few years now, and agmatine sulfate has been the most effective I've yet tried for mood; it quiets negative thought cycles without making me feel robotic, puts me on a positive mood curve (more smiles and laughter), and has improved my sleep—with no perceptible negative side effects (at 1g twice a day). Grateful to have found this.

  • 4
    agmatine

    Posted by lloyd shifflett on 14th Apr 2023

    works

  • 5
    Very Satisfied

    Posted by Tramere M on 12th Mar 2023

    Amazing results. I am very happy with this Agma! It's pure, it really works wonders. I have a clear head, energized and focused.

  • 5
    Great

    Posted by Tina Kalter on 18th Feb 2023

    I can really tell a difference when I take this. It helps other things I take work better. In the beginning it did make me a little edgy but after I got used to it, which I almost gave up, I really enjoy it now.

  • 5
    Agmatine sulfate

    Posted by ND_enthusiast on 23rd Jan 2023

    Since the moment i put the first capsule in my mouth i had a subtle but noticeable change of headspace. This stuff works amazingly well for mood, helps me with common side effects and is quells down stress without increasing my attention issues ... its still too soon to tell how it will play out but ive sped up the process by attack dosing it (2 grams per day but planning on sticking to the recommended dosage eventually). My dreams are more vivid sleep is more restful and mood is an ideal balance between relaxed and awake. Also mixing it with magnesium is the best sleeping stack I've ever tried. Any side effect I've ever experienced both from my meds i now long gone and forgotten. I new i was going to love this substance because this and magnesium are the only exception I've made ever since starting treatment regarding the no nootropics vow i had given myself. The real reason though im writting this report is out of respect for the amazing customer service of nootropics depot their fast delivery and my previous consistent 5/5 experience i had with every product ive ever bought from them. All pharmaceutical grade dependable reasonably priced. I felt i had post a review a long time now and since agmatine looks like my soon to be new love affair i thought id grab the chance and give my honest appreciation to everything that these guys have done for me and for improving my life. Its so sad i live in europe and i have to wait so long with the standard air mail and pay customs on top of it. If only you guys had a second store in europe it would have saved m so much hustle.

  • 5
    Absolutely Amazing

    Posted by Audaine on 8th Dec 2022

    Agmatine has so far helped me develop a newfound combination of focus and sociability. I stay at the minimum amount, as anymore than that somehow gets rid of the anxiolytic effects that it has.

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*Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.