Agmatine sulfate is a common amino acid derived from L-arginine that’s involved in protein synthesis. When L-arginine undergoes decarboxylation, a process that results in the removal of a carboxylic acid group, it converts into agmatine sulfate. Agmatine sulfate is stored in neurons within the brain and gets released when those neurons are activated.
Agmatine sulfate is regarded as a neuromodulator and neurotransmitter which may explain some of the Agmatine sulfate nootropic benefits some people tend to experience. As a nootropic, Agmatine sulfate offers a diverse profile of potential Agmatine sulfate benefits for brain health and function as well as overall fitness.
Agmatine benefits may involve an array of organs and bodily systems to help promote overall health. Agmatine sulfate’s interaction with NMDA and Nitric oxide receptors have been shown to promote several elements of cognitive function and brain health. In particular, these results focused heavily on memory and learning abilities. Research on Agmatine benefits on animals uncovered Agmatine sulfate’s ability to support healthy oxidation levels. It is believed that this may be a result of Agmatine’s capacity to limit glutamate activity. High glutamate activity can potentially induce over-excitation in the brain. This over-excitation is known as excitotoxicity. Excitotoxicity can cause nerve cells to degrade due to being overactivated.
As far as how this translates to Agmatine sulfate nootropic effects, Agmatine seems to interact with a few neurotransmitter pathways and systems. When it comes to glutamate receptors, studies found that Agmatine appears to act strongly on these receptors and pathways. Research has found that Agmatine levels tend to increase in some regions of the brain when engaged in a learning process. Agmatine even appeared to exert some influence in memory formation in these areas. Taking an Agmatine supplement may help support memory formation events which may increase overall cognitive function with an emphasis on learning and memory.*
Agmatine has also forged a reputation in the bodybuilding community for its ability to create massive muscle pumps via its Nitric oxide regulation. Nitric oxide is a compound that’s naturally produced in our bodies and plays an important role in cell signaling and communication throughout the entire system. Anecdotal reports suggest that this enhanced connection may also promote feelings of well being. Agmatine sulfate is highly utilized as a main ingredient in various pre-workout formulas and “pump” supplements. In fact, it’s very common among bodybuilders to pair a pre-workout with agmatine sulfate. Some athletes swear by the agmatine sulfate bodybuilding benefits. As if boosting Nitric oxide levels and promoting cognitive function weren’t enough agmatine benefits for you, Agmatine sulfate also appears to support blood flow by behaving as a calcium antagonist. Research has found that this interaction may help widen and soothe blood vessels which in turn may support overall cardiovascular function. What’s even better, is that Agmatine may help create lean muscle mass and may even promote muscle definition. This makes Agmatine sulfate one of the best muscle pump supplements out there!
Agmatine sulfate also appears to interact with NMDA glutamate receptors. When these receptors get activated, they allow ions with a positive charge to pass through cell membranes. NMDA receptors are also one of the major glutamate receptors involved in regulating synaptic plasticity and memory functions. Synaptic plasticity is important for the ability of signals between nerves to strengthen or weaken over time. A healthy level of synaptic plasticity means signals are more effectively communicated between neurons.
As a dietary supplement, take one 250mg Agmatine Sulfate capsule 1-2 times daily.
To gain more insight, read the Agmatine sulfate reviews and experiences below.
Nootropics Depot offers 60ct. or 120ct. jars of high quality Agmatine Sulfate capsules. Nootropics Depot's Agmatine Sulfate has been lab tested for product purity and identity.
You may also be interested in agmatine sulfate powder.
| *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
This is the best supplement available period. It does a lot of wonderful things, and Nootropics Depot always delivers the best highest purity supplements with super quick shipping! I find that Agmatine does many really good things for me: 1. Feeling of calm or peace for about 2-4 hours 2. Reduction of tolerance to almost everything 3. Potentiates almost everything 4. Increased "pumps" at the gym - just feels like a larger blood rush to the muscles.
My intended use was for athletic performance. It definitely increases blood flow to muscles in response to training, similar to arginine alpha ketoglutarate. The decrease in pain threshold was odd, but not unbearable. I would recommend only taking on workout days about 30 minutes to 1 hour prior to the start of exercise. I take other nootropics so it would be hard to isolate any mental benefits from this alone.
This is the best supplement available period. It does a lot of wonderful things, and Nootropics Depot always delivers the best highest purity supplements with super quick shipping! I find that Agmatine does many really good things for me: 1. Feeling of calm or peace for about 2-4 hours 2. Reduction of tolerance to almost everything 3. Potentiates almost everything 4. Increased "pumps" at the gym - just feels like a larger blood rush to the muscles.
My intended use was for athletic performance. It definitely increases blood flow to muscles in response to training, similar to arginine alpha ketoglutarate. The decrease in pain threshold was odd, but not unbearable. I would recommend only taking on workout days about 30 minutes to 1 hour prior to the start of exercise. I take other nootropics so it would be hard to isolate any mental benefits from this alone.
Seems to be more effective than other nootropics. Agmatine sulf is not promoted much but produces better results than some promoted nootropics on areas of attention & mood. Needs to be taken about 2-3 weeks to notice effects. Apparantly it is highly bioavailable so its absorbed well.
Nootropics Depot provides great quality products and I trust them for that. From my experience it is great for pumps in the gym anywhere from 500-1000mg. Also, if you use sparingly, gives a great feeling of overall well being in the same dosage. Supposedly lowers tolerance to certain herbs or drugs, but does not work as well as abstinence for some time in that regard.
