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100% Vegan Lactose Free Gluten Free GMO Free
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100% Vegan Lactose Free Gluten Free GMO Free

Agmatine Sulfate Powder

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label-lactose-free:
true
label-gluten-free:
true
label-gmo-free:
true
label-vegan:
true
label-vegetarian:
true
info-dose:
250mg (Per Serving)
info-dose-timing:
Flexible
info-dose-frequency:
1-2 Times Daily
info-how-to-take:
With Or Without Food
benefits-effect-days:
1-2 Weeks (With Immediate Effects)
page-fact-checked:
false
research-snapshot-summary:
Agmatine sulfate, derived from L-arginine, is involved in protein synthesis. It may support cognitive function, aid in pain management, offer neuroprotective effects, and help prevent oxidative stress by reducing inflammation and protecting mitochond
Form:
Powders
no-scoop:
true
Dietary Restrictions:
Lactose Free
Dietary Restrictions:
Gluten Free
Dietary Restrictions:
Non-GMO
Dietary Restrictions:
Vegan
Dietary Restrictions:
Vegetarian
Type:
Nootropics
Type:
Amino Acids
Type:
Pre-Workout
disable-paypal:
true
lab-testing:
AGSS1021524 | AGSS1021524_250g_signed.pdf
lab-testing:
AGSS1110723 | AGSS1110723_125g_signed.pdf
lab-testing:
AGSS1052324 | AGSS1052324_125g_Signed.pdf
lab-testing:
AGSS1061024 | AGSS1061024_250g_Signed.pdf
lab-testing:
AGSS1092324 | AGSS1092324_250g_Signed.pdf
lab-testing:
AGSS1102924 | AGSS1102924_125g_signed.pdf
$20.99 - $33.99
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Product Usage

Dose Dose

250mg (Per Serving)

Dose Timing Dose Timing

Flexible

How to Take How to Take

With Or Without Food

Dose Frequency Dose Frequency

1-2 Times Daily

Summary

Agmatine sulfate, derived from L-arginine, is involved in protein synthesis. It may support cognitive function, aid in pain management, offer neuroprotective effects, and help prevent oxidative stress by reducing inflammation and protecting mitochond

ATTENTION EUROPEAN CUSTOMERS: Some EU countries consider agmatine a novel food ingredient, and may not allow it through customs. Please look up your country's specific regulations before purchasing.

What is Agmatine Sulfate Powder?

Agmatine sulfate is a biogenic compound derived from L-arginine, a common amino acid involved in the synthesis of proteins. When L-arginine undergoes decarboxylation, a process that results in the removal of a carboxylic acid group, it becomes agmatine sulfate. This compound is stored in the neurons of the brain and released when those neurons are activated. The process of creating and storing Agmatine sulfate sets it apart from its amino acid counterpart. Agmatine sulfate is considered a neurotransmitter or neuromodulator which could explain some of the Agmatine sulfate nootropic effects some people experience. As a nootropic, agmatine sulfate offers a wide range of potential benefits to your brain health and general fitness.

Agmatine Sulfate Benefits and Uses

    • May help support positive emotional outlook*
    • May help promote restful sleep*
    • May help support immune system function*
    • May help promote overall strength and endurance*
    • May help support digestive health*
    • May help promote cognitive function*

Agmatine Sulfate Bodybuilding and Nootropic use

Agmatine sulfate benefits may impact a wide range of organs and systems to potentially improve overall health. The interaction between Agmatine sulfate with nitric oxide and NMDA receptors have been shown to support various elements of cognitive function and overall health. In particular, these findings focused primarily on memory and learning abilities.

Studies on Agmatine sulfate have also shown Agmatine sulfate’s ability to promote healthy levels of oxidation. Part of this ability may come from Agmatine’s ability to limit glutamate activity. High glutamate activity can potentially cause over-excitation in the brain, leading to something known as excitotoxicity. Excitotoxicity leads to degradation of nerve cells as a result of receptors being overactivated.

As far as how this translates to Agmatine sulfate nootropic effects, Agmatine appears to interact with several neurotransmitter systems and pathways. Agmatine appears to interact pretty strongly with glutamate receptors and pathways in particular. Studies have actually shown that Agmatine levels rise in some regions in the brain when learning something. Agmatine even appears to have a significant role in memory formation in these areas. So, taking an agmatine supplement may help promote memory formation events which may as a whole increase cognitive function focused on memory and learning.*

Agmatine has built itself a reputation in the bodybuilding community for its ability to create huge muscle pumps through its Nitric oxide regulation. Nitric oxide is a compound naturally produced in your body that plays a role in cell signaling and communication throughout your entire system. Anecdotally, this enhanced connection also may promote one’s sense recognition and support feelings of well being. Agmatine sulfate is even used as an ingredient in various pre-workouts and “pump” supplements. In fact, it’s quite common to pair a pre-workout with agmatine sulfate and some athletes swear by the agmatine sulfate bodybuilding benefits. 

As if boosting Nitric oxide levels weren’t enough, Agmatine sulfate also appears to support blood flow by acting as a calcium antagonist. Studies have found that this mechanism of action may help soothe and widen blood vessels which may help support overall cardiovascular function. What’s even better, is that Agmatine may help produce lean muscle mass and may even help enhance muscle definition. This makes Agmatine sulfate one of the best muscle pump supplements out there!*

How Agmatine Sulfate May Promote Cognitive Function*

Agmatine sulfate also appears to interact with NMDA glutamate receptors. Once these receptors are activated, they allow positively charged ions to flow through cell membranes. NMDA receptors are also one of the key glutamate receptors involved in regulating memory functions and synaptic plasticity. Synaptic plasticity is important for the ability of signals between nerves to strengthen or weaken over time. A healthy level of synaptic plasticity means signals are more effectively communicated between neurons.

How to take Agmatine Sulfate and Agmatine Sulfate Dosage

As a dietary supplement, take 250mg of Agmatine sulfate 1-2 times daily. 

Agmatine Sulfate Reviews

To learn more, read the Agmatine sulfate reviews and experiences below.

Where to Buy Agmatine Sulfate Powder?

Nootropics Depot offers 125g or 250g jars of high quality Agmatine sulfate powder. Nootropics Depot's Agmatine sulfate has been lab-tested and verified for both product purity and identity.

You may also like Agmatine sulfate capsules

 *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Reviews

  • 5
    Surprise! It worked for me

    Posted by Kim V on 19th Oct 2020

    I've tried so many things. My main issues are 1) debilitating anxiousness that presents itself much different. It just makes me unable to do tasks, but no panic attacks, sweats, etc. Just extreme procrastination as I get a deep aversion/fear of tasks. Overnight, this helped that. I was able to do a task I'd avoided for 3 weeks. 2) Daily sinus blockage from a dust mite allergy. This made me able to breathe. 3) Mood - I just feel better. I have a whole closet of things I've tried & this one is best. Ashwagandha wasn't reliable, rhodiola helped but then caused the side effect of depression.

  • 5
    Levels me out.

    Posted by B. Alexander on 16th Oct 2020

    The one amino I incorporate most. Definitely calms me down. I tend to operate with a frantic, anxious, high strung energy. This doesn't knock me on my ass, but helps me operate on an even keel. I assume this effect is to do with Nitric oxide levels in the brain being lowered. I take 250mg in morning, and took 250mg at night at first, but I believe it was disrupting my sleep a bit, so I found that second dose on an empty stomach before dinner/early evening was the best. Great product.

  • 5
    Good mood and sleep

    Posted by donatelo on 6th Mar 2020

    That was unexpected but agmatine improves my mood and makes my sleep deeper. It feels like a mild psychedelic in a way. This is now a part of my base stack.

  • 5
    Varied uses and effects

    Posted by Jason on 25th Feb 2019

    relieve a small amount of anxiousness. it also bulked my muscles up to near the size they were when I was heavy into bodybuilding, without me having to exercise at all. Must be a muscle memory effect. Also, my appetite went out of control. It also helped my mother with her anxiousness more than me. It helped her with pain management to a mild degree.

  • 3
    Very subtle

    Posted by Unknown on 16th Jan 2019

    This substance has glowing reviews, but I haven't got any benefit. It's hard to tell if it really does something.

  • 5
    agmatine

    Posted by Mario on 1st Oct 2018

    I'm very satisfied with your brand and business ... I take agmatine about 750mg once and it looks like l arginine, for a more comprehensive answer I need more time and full usage.

  • 5
    Great Service and Quick shipping

    Posted by Unknown on 27th Aug 2018

    Highly recommended ++++++

  • 5
    great product

    Posted by Unknown on 20th Jul 2018

    Good quality product. Works well to maintain tolerances to other substances. By itself, it brings you more into the moment, which helps with concentration.

  • 5
    amazing batch

    Posted by citrus on 15th Jul 2018

    They say it has an effect when combined with MJ. That's probably why I don't notice it as much now: I don't have any MJ in my system. It also synergizes with lots of other things as well. I think people who are prescribed stims should take this at night. Like 250mg of it. It prevents tolerance/excitotoxicity and causes the brain tissues to create more neurotransmitters. I think it does a lot to help prevent adrenal exhaustion from stims. However if you take it during the day it's not a very good combination because you will be less productive and no amount of coffee will able to undo that.

  • 4
    if you want to stay awake all night

    Posted by TERESA on 5th Apr 2018

    Hi I am very new to nootropics and I am really still Experimenting with these . I have not found the right thing yet . I felt like agmatine Did help me to go to sleep a couple nights. I took 750 mg. I have also been taking phenylpiracetam and adrafinil and noopept along with choline The Choline I purchased at the health food store. Sometimes it makes me feel like I’m actually tired from taking it so maybe I just don’t know what I’m doing but I think they are probably very good products and I’m going to keep Trying.

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*Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.