About Andrographis paniculata Powder

Andrographis paniculata powder provides 50% andrographolides, the primary bioactive compounds responsible for this herb's traditional benefits. Known as the "King of Bitters" in Traditional Chinese Medicine and Ayurveda, this standardized extract supports healthy immune function, supports a healthy inflammatory response, and supports cellular protection against oxidative stress.

Our Andrographis Story

For years, we watched customers struggle with standardization inconsistencies in andrographis products. While this herb has centuries of traditional use backing its benefits, most extracts on the market varied wildly in andrographolide content, making it impossible to achieve reliable effects. Without proper standardization, users couldn't trust whether they were getting optimal levels of the active compounds.

We partnered with specialized extraction facilities to develop a rigorously standardized andrographis extract that guarantees 50% minimum andrographolides content by UPLC analysis. This high concentration delivers consistent levels of the bioactive compounds responsible for supporting healthy inflammatory responses and cellular health supplements. Every batch undergoes comprehensive third-party testing to verify both purity and potency, giving you the reliability that traditional andrographis preparations simply can't match.

Benefits

• Supports Immune Function: Andrographis supports healthy immune system response and respiratory function through its high concentration of andrographolides, helping the body maintain natural defenses.
• Supports a Healthy Inflammatory Response: The bioactive compounds in andrographis promote a healthy inflammatory response throughout the body, supporting overall health and comfort.
• Supports Protection From Oxidative Stress: Andrographolides support healthy oxidative balance, providing anti oxidative stress supplements support for cellular integrity and function.
• Supports Healthy Neurological Function: Research suggests andrographis supports cognitive function through its effects on inflammatory and oxidative pathways in the brain, promoting healthy neurological function.

Andrographis paniculata also supports respiratory health and overall organ function. This herb has been used traditionally in Ayurvedic and Traditional Chinese Medicine for promoting cellular health supplements, and modern research now shows how its andrographolide content supports healthy cellular processes throughout the body.

Quality and Standardization

• Standardized Potency: Our andrographis powder is standardized to a minimum of 50% andrographolides by HPLC analysis, ensuring consistent delivery of the primary bioactive compounds responsible for this herb's immune-supporting effects.
• Third-Party Testing: Each batch undergoes comprehensive testing for purity, potency, and contaminants including heavy metals, pesticides, and microbials to guarantee product safety and quality standards.
• Premium Sourcing: We source our andrographis paniculata from established cultivation regions in Southeast Asia where optimal growing conditions naturally concentrate the beneficial andrographolide compounds.
• Identity Verification: Advanced analytical methods confirm the botanical identity and chemical profile of our extract, ensuring you receive authentic andrographis paniculata with verified lung health support properties.
• Powder Form Advantages: Our fine powder format allows for precise dosing flexibility and can be easily incorporated into various delivery methods while maintaining the full spectrum of bioactive compounds found in traditional preparations.

Mechanism of Action

• NF-κB Pathway Support: Andrographolides support healthy nuclear factor-kappa B (NF-κB) activity, a key inflammatory signaling pathway that regulates immune responses and cellular stress reactions.
• Cytokine Balance: The active compounds support healthy cytokine production, helping maintain balanced immune system communication and supporting healthy inflammatory responses throughout the body.
• Antioxidant Enzyme Support: Andrographolides support endogenous antioxidant systems by promoting superoxide dismutase and catalase activity, providing cellular health protection against oxidative stress.
• Respiratory Epithelial Support: The bioactive compounds interact with respiratory tract tissues to support mucosal integrity and maintain healthy barrier function in the lung health support supplements category.
• Hepatic Support: Andrographolides support healthy liver function by promoting detoxification enzyme activity and supporting hepatocytes against oxidative stress through multiple cellular pathways.

Overview of the Science

Research demonstrates that andrographis supports healthy immune function through multiple molecular mechanisms. Studies show andrographolides modulate immune cell activity, with one clinical trial finding enhanced natural killer cell function and improved antibody responses in healthy adults [1,2,3]. The compounds work by supporting a healthy inflammatory response through modulation of NF-κB and MAPK signaling pathways, promoting healthy cytokine production while supporting balanced immune responses [4,5]. Additionally, andrographis provides antioxidant support, protecting cells from oxidative stress through scavenging free radicals and supporting endogenous antioxidant enzyme systems [6,7,8].

Clinical research has particularly focused on andrographis for respiratory health, with systematic reviews indicating its effectiveness for upper respiratory tract symptoms and recent studies exploring its potential in viral respiratory infections [9,10]. The herb's bioactive compounds appear to support healthy respiratory function through their properties that support a healthy inflammatory response and immune modulation, making it a valuable addition to comprehensive lung health support supplements regimens. These effects are dose-dependent, with standardized extracts containing higher concentrations of andrographolides showing more pronounced benefits in clinical trials.

[1] Rajanna S, Tiwari V, Devi P, et al. Immunomodulatory effects of Andrographis paniculata extract in healthy adults – An open-label study. J Ayurveda Integr Med. 2021;12(3):470-476.

[2] Kumar RA, Sridevi K, Kumar NV, Nanduri S, Rajagopal S. Anti[...] and immunostimulatory compounds from Andrographis paniculata. J Ethnopharmacol. 2004;92(2-3):291-295.

[3] Sheeja K, Kuttan G. Modulation of natural killer cell activity, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by andrographolide in normal and Ehrlich ascites [...]-bearing mice. Integr [...] Ther. 2007;6(1):66-73.

[4] Li Y, He S, Tang J, et al. Andrographolide inhibits inflammatory cytokines secretion in LPS-Stimulated RAW264.7 cells through suppression of NF-κB/MAPK signaling pathway. Evid Based Complement Alternat Med. 2017;2017:8248142.

[5] Wang DW, Wu L, Tang JJ, et al. Study of anti-inflammatory activities of the pure compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene expression. Int Immunopharmacol. 2010;10(9):995-1006.

[6] Zhang XF, Tan BK. Antioxidant action of Andrographis paniculata on [...]. Methods Find Exp Clin Pharmacol. 2007;29(8):543-546.

[7] Singh RP, Banerjee S, Kumar PV, Raveesha KA, Rao AR. Evaluation of beneficial effects of antioxidant properties of aqueous leaf extract of Andrographis paniculata in STZ-induced [...]. Mol Cell Biochem. 2009;328(1-2):179-185.

[8] Mussard E, Jousselin S, Cesaro A, et al. Andrographis paniculata and Its Bioactive Diterpenoids Against Inflammation and Oxidative Stress in Keratinocytes. Antioxidants (Basel). 2020;9(6):530.

[9] Coon JT, Ernst E. Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med. 2004;70(4):293-298.

[10] Benjaponpitak A, Sawaengtham T, Thaneerat T, et al. Effect of Andrographis paniculata treatment for nonimmune patients with early-stage [...] on the prevention of pneumonia: A retrospective cohort study. Arch Intern Med Res. 2023;6(2):35-43.

Ingredients

Andrographis paniculata Extract:

• Andrographis paniculata (leaf)
• 50% Andrographolides
• 200mg per serving

The 50% andrographolide standardization represents one of the highest concentrations available in the supplement market. Most andrographis extracts contain only 10-20% andrographolides, making this extract significantly more potent. Andrographolides are the primary bioactive compounds responsible for andrographis's beneficial effects, so this high standardization ensures you receive maximum potency in every serving. This concentration allows for effective dosing while maintaining the full spectrum of compounds naturally present in the andrographis leaf.