About AvailOM High EPA Capsules

AvailOM High EPA is a patented fish oil supplement featuring a unique 2:1 EPA to DHA ratio (30% EPA, 15% DHA) enhanced with lysine complexation technology. This specialized formulation delivers 5-fold better absorption compared to standard fish oils, making it one of the most bioavailable sources of EPA available for supporting cardiovascular health, mood balance, and cognitive function.

Our AvailOM High EPA Story

We recognized a major gap in the fish oil market: finding a supplement specifically rich in EPA was nearly impossible. Most fish oils heavily favor DHA or provide equal ratios, but EPA offers unique benefits for cardiovascular function and mood support that many people couldn't access effectively. The few high-EPA products that existed suffered from poor absorption rates, requiring massive doses to achieve meaningful benefits.

AvailOM High EPA combines an optimal EPA-focused ratio with patented lysine complexation technology. This approach dramatically improves bioavailability while enhancing the stability of the omega 3 supplements. The result is a fish oil that delivers superior EPA levels at lower doses, making it easier to obtain the cardiovascular and mood benefits that EPA uniquely provides without the large capsule burden of traditional fish oils.

Benefits

• Beneficial To Cardiovascular Health: EPA supports healthy prostaglandin I3 levels, promoting proper vasodilation and platelet function while inhibiting the NLRP3 inflammasome that plays a key role in cardiovascular wellness.
• Enhances Mood: EPA converts to endocannabinoids like EPA-EA and its metabolite 17,18-EEQ-EA, which interact with the endocannabinoid system to support a balanced mood and positive emotional state.
• Supports Cognitive Function: As an essential omega-3 fatty acid, EPA helps maintain optimal brain health and supports various aspects of cognitive performance and mental clarity.
• Reduces Inflammation: Through its endocannabinoid effects and interaction with inflammatory pathways, EPA promotes a healthy inflammatory response throughout the body and provides natural pain and inflammation support.

The lysine complexation technology in AvailOM High EPA creates a stable molecular bond that protects the omega-3 fatty acids from oxidation while dramatically improving their absorption in the digestive tract. Enhanced stability delivers consistent potency from each capsule, while the superior bioavailability allows for effective results at lower doses compared to traditional omega 3 supplements.

Quality and Standardization

• Patented Lysine Complexation Technology: Our AvailOM utilizes proprietary lysine absorption technology that complexes EPA and DHA molecules, improving overall bioavailability by approximately 5-fold compared to standard fish oil formulations.
• Standardized EPA:DHA Ratio: Each capsule is precisely standardized to deliver 30% EPA and 15% DHA, ensuring consistent potency and the optimal 2:1 ratio that maximizes EPA's cardiovascular and mood benefits.
• Enhanced Stability Profile: The lysine complexation process significantly improves the stability of omega-3 fatty acids, reducing oxidation and maintaining potency throughout the product's shelf life.
• Third-Party Verified Purity: Every batch undergoes comprehensive testing for heavy metals, PCBs, dioxins, and other contaminants to ensure pharmaceutical-grade purity and safety standards.

Mechanism of Action

• Lysine Complexation Technology: The proprietary lysine absorption enhancement system works by forming stable complexes with EPA and DHA molecules, protecting them from degradation in the digestive tract and facilitating transport across intestinal membranes for superior bioavailability.
• Endocannabinoid Pathway Activation: EPA serves as a precursor to specialized endocannabinoids like eicosapentaenoyl ethanolamide (EPA-EA) and its metabolite 17,18-EEQ-EA, which interact with the endocannabinoid system to influence mood regulation and pain and inflammation responses.
• Prostaglandin I3 Modulation: EPA promotes the production of prostaglandin I3, a potent signaling molecule that helps regulate vasodilation and platelet aggregation, supporting optimal cardiovascular function through these direct vascular effects.
• NLRP3 Inflammasome Inhibition: EPA acts as a natural inhibitor of the NLRP3 inflammasome, a key inflammatory protein complex involved in cardiovascular health, helping maintain balanced inflammatory responses throughout the cellular health system.

Overview of the Science

Clinical research has demonstrated EPA's significant role in supporting cardiovascular health through multiple mechanisms. Studies show that high-dose EPA supplementation helps maintain healthy triglyceride levels and supports proper endothelial function [1][2]. EPA works by influencing prostaglandin I3 production, a key mediator that promotes healthy vasodilation and supports optimal platelet aggregation patterns. Additionally, EPA acts as an inhibitor of the NLRP3 inflammasome, a critical component in maintaining cardiovascular wellness. The enhanced bioavailability of AvailOM's lysine-complexed formula means these cardiovascular benefits can be achieved with lower dosing compared to conventional omega 3 supplements [7][8].

Research into EPA's mood and cognitive effects reveals promising mechanisms involving the endocannabinoid system. EPA serves as a precursor to specialized endocannabinoids like EPA-EA and EPG, which interact with cannabinoid receptors to influence mood regulation [3][4]. Clinical trials demonstrate that EPA supplementation supports healthy mood in individuals with elevated inflammatory markers, while also showing benefits for global cognitive function [5][6]. The superior absorption provided by AvailOM's lysine complexation technology ensures optimal delivery of these mood-supporting compounds to target tissues, making it particularly valuable for those seeking comprehensive brain health supplements.

[1] Khan SU et al. EClinicalMedicine. 2021;38:100997.

[2] Bhatt DL et al. N Engl J Med. 2019;380(1):11-22.

[3] Mischoulon D et al. J Clin Psychiatry. 2022;83(5):21m14074.

[4] Liao Y et al. Transl Psychiatry. 2019;9(1):190.

[5] Stonehouse W et al. Am J Clin Nutr. 2013;97(5):1134-1143.

[6] Jackson PA et al. Am J Clin Nutr. 2022;115(4):1054-1064.

[7] Manusama K et al. Prostaglandins Leukot Essent Fatty Acids. 2021;164:102204.

[8] Schuchardt C et al. Food Nutr Res. 2024;68:11028.

Ingredients

AvailOM High EPA Fish Oil:

• 225mg Total Omega-3 fatty acids per capsule
• 150mg EPA (Eicosapentaenoic Acid)
• 75mg DHA (Docosahexaenoic Acid)
• Fish Oil L-Lysine Complex for enhanced absorption

The Fish Oil L-Lysine Complex represents a significant advancement in omega-3 bioavailability. This proprietary formulation bonds the fish oil to L-lysine, creating a more stable and absorbable form that resists oxidation and delivers omega-3 fatty acids more effectively than standard fish oil capsules. The 2:1 EPA to DHA ratio provides concentrated eicosapentaenoic acid support while maintaining the synergistic benefits of both essential fatty acids.