About Cyanidin 3-Glucoside (C3G)

Cyanidin 3-Glucoside (C3G) is a striking purple anthocyanin naturally found in dark-hued fruits like blackberries and blueberries. Our supplement delivers 125mg of standardized C3G derived from premium black rice extract, offering powerful support for nutrient partitioning and metabolic health. C3G provides versatile wellness benefits for cognitive function, metabolic health, focus and mood, making it a valuable addition to any supplement regimen.

Our C3G Story

We discovered Cyanidin 3-Glucoside while researching compounds that could optimize nutrient partitioning and metabolic function without the harsh side effects common in similar products. The challenge was finding a standardized extract that could deliver consistent, bioavailable C3G while maintaining the integrity of this delicate anthocyanin compound.

We source premium black rice extract standardized for C3G content and developed a specialized extraction process that preserves the compound's potency. Many of us at Nootropics Depot have experienced its energizing effects firsthand, particularly when paired with caffeine, making it an excellent choice for busy mornings or demanding workdays. C3G supports multiple pathways simultaneously, promoting metabolic health while enhancing cognitive function in a single, well-rounded supplement.

Benefits

• Reduces Oxidative Stress: This purple anthocyanin acts as a potent antioxidant, protecting your cells from free radical damage that accumulates from daily stress and environmental factors.
• Supports Gut Health: C3G promotes a healthy digestive environment, supporting the beneficial bacteria in your gut that play a crucial role in overall wellness and energy production.
• Boosts Metabolic Processes: Enhances insulin sensitivity and optimizes nutrient partitioning, directing nutrients toward muscle growth while supporting balanced energy levels throughout the day.
• Supports Brain Health: Promotes mental clarity and focus similar to the cognitive benefits from consuming antioxidant-rich berries, while offering neuroprotective benefits for long-term brain wellness.

C3G creates unique synergy with caffeine for fitness enthusiasts and busy professionals, amplifying the stimulant's effects for clean, sustained energy without the jitters. This natural compound helps you feel more energized and motivated while supporting your body's ability to efficiently use the nutrients you consume.

Quality and Standardization

• Premium Extract Standardization: Our Cyanidin 3-Glucoside is derived from premium-grade black rice extracts that are meticulously standardized for purity and potency to ensure consistent anthocyanin content in every capsule.
• Rigorous Testing Protocol: Each batch undergoes comprehensive in-house and third-party testing to verify it meets our stringent safety and efficacy standards before reaching customers.
• Transparency You Can See: We openly share details about our sourcing and testing processes, allowing you to access complete information about what you're taking and how it's produced.
• Quality-Controlled Manufacturing: From raw material selection to final product packaging, every step in our manufacturing process is designed to deliver consistent quality you can trust.

Mechanism of Action

• Antioxidant Pathway Activation: C3G activates the Nrf2 pathway to stimulate the body's natural antioxidant enzyme production while suppressing inflammatory pathways like NF-κB, providing dual protection against oxidative damage and inflammation.
• Metabolic Enhancement: The compound enhances insulin sensitivity by promoting glucose uptake into cells, supporting balanced energy levels and efficient nutrient utilization throughout the body.
• Neurotransmitter Support: By inhibiting monoamine oxidase enzymes that break down dopamine and serotonin, C3G helps maintain healthy levels of these crucial neurotransmitters for mood regulation and cognitive function.
• Caffeine Synergy: These combined mechanisms explain C3G's ability to enhance caffeine's effects, offering both sustained physical energy and improved mental clarity when used together.

Overview of the Science

The scientific exploration of Cyanidin 3-Glucoside continues to reveal its impressive range of benefits across various areas of health. Research highlights its strong antioxidant properties, showing how it reduces oxidative stress in cells while protecting tissues from free radical damage. Studies on gut health suggest that C3G helps maintain intestinal integrity by reducing inflammation and supporting mucosal balance—key factors for digestive wellness.

In the realm of metabolism, research indicates that C3G improves insulin sensitivity and glucose regulation, contributing to better energy balance and nutrient partitioning. Neurological studies provide further intrigue; findings suggest that C3G protects neurons from oxidative damage while enhancing cognitive function through monoamine oxidase inhibition [1]. While ongoing research will undoubtedly uncover even more about this remarkable compound, current evidence underscores its potential as a powerful tool for both physical and mental well-being.

[1] Wei J, Zhang G, Zhang Y, et al. Cyanidin-3-O-glucoside, cyanidin, and oxidation products of cyanidin protect neuronal function through alleviating inflammation and oxidative damage. J Food Sci. 2022;87(4):1670-1686.

Ingredients

Cyanidin 3-Glucoside:

• 250mg per serving
• Sourced from 1,000mg Oryza sativa Extract (seed)
• Vegetable cellulose capsules

This standardized extract delivers a concentrated dose of cyanidin 3-glucoside, one of the most studied anthocyanins found in black rice. The 4:1 concentration ratio means each 250mg serving represents the active compounds from 1,000mg of raw Oryza sativa seed extract. This standardization ensures consistent potency and bioavailability, providing reliable levels of this powerful anthocyanin compound that supports cellular health and antioxidant activity.