null Skip to main content

(-)- Epicatechin 90% Powder

Standardized to 90% purity for muscle growth, cardiovascular health, and cognitive function support.

(12 Reviews) Write a Review

View All Reviews

(-)- Epicatechin 90% Powder

Standardized to 90% purity for muscle growth, cardiovascular health, and cognitive function support.

(12 Reviews) Write a Review

View All Reviews

Available in multiple forms! Click Here for:
  • 90% Pure (-)-Epicatechin Extract
  • Supports Muscle Growth via Myostatin
  • Enhances Cardiovascular & Cognitive
  • Non-Hormonal Muscle Building Compound

3rd Party Lab Tested & Verified

See Why ND Epicatechin Is The Best

Updated On: 05/23/2026

$29.99 - $64.99

Order within to ship today

Your order will be shipped tomorrow

Adding to cart… The item has been added
ATTENTION: This product does not include a scoop. Learn more

Benefits

When You'll Notice Effects

2-3 Weeks (With Immediate Effects)

(-)-Epicatechin is a flavanol found in green tea and dark chocolate. It supports muscle growth, cardiovascular health, cognitive function and physical performance in healthy adults.

  • Muscle Mass
  • Cardiovascular
  • Cognition
  • Physical Energy

Why ND Epicatechin?

The highest purity epicatechin we tested at 90% standardization
test

How To Take

Dose
Dose

200mg (Per Serving)

Timing
Timing

Flexible

How to Take
How to Take

With Or Without Food

Frequency
Frequency

1 Time Daily

Reddit Icon

Talk to thousands of customers just like you.

Join our community on Reddit to ask questions, share experiences, and get the unfiltered truth from long-term users. We believe in letting our customers speak for themselves, so you can hear the real story from people just like you.

Visit Our Subreddit

Build Your Stack

Unlock your full potential by building a supplement stack tailored to your unique goals. Whether you're focused on energy, focus, or overall wellness, we’re here to guide you in creating the perfect combination of supplements to support your journey. Your health, your way—powered by the right stack.

  • About (-)- Epicatechin 90% Powder

    (-)-Epicatechin 90% is a highly concentrated extract of the bioactive flavanol found naturally in green tea and dark chocolate. Standardized to 90% purity, our extract delivers potent levels of this compound that supports healthy muscle function, promotes cardiovascular health, and supports cognition through healthy blood flow.

    Our (-)-Epicatechin Story

    We looked at the supplement market for epicatechin products and found most extracts offering low concentrations with unclear standardizations. Many products claimed epicatechin content without specifying purity or providing analytical verification. Consumers seeking the muscle and cognitive benefits documented in research needed a reliable, highly concentrated source.

    We developed a 90% pure (-)-epicatechin extract with rigorous analytical testing to ensure consistent potency. We source our epicatechin from high-quality plant material and use advanced extraction techniques to concentrate the active isomer while removing impurities. Every batch undergoes comprehensive lab testing to verify the 90% standardization, giving you the dosing levels used in clinical research on follistatin support and fitness enhancement.

    Benefits

    • Promotes Muscle Function And Strength: Supports supplements for muscle growth through myostatin regulation and follistatin enhancement, helping maintain healthy muscle tissue development and strength gains.
    • Supports Cardiovascular Function: Promotes healthy blood flow and circulation, contributing to overall heart health and vascular function in active individuals.
    • Benefits Cognitive Tasks: Supports memory and executive function through healthy cerebral blood flow and neuronal support.
    • Supports Physical Performance: Supports energy levels and endurance capacity, helping users feel stronger and more energized during training and daily activities.

    (-)-Epicatechin also supports healthy testosterone levels naturally, providing additional benefits for strength, recovery, and overall vitality.

    Quality and Standardization

    • 90% Purity Standardization: Our (-)-Epicatechin extract is standardized to deliver 90% purity levels through advanced extraction and purification processes, ensuring consistent potency in every serving.
    • HPLC Testing Verification: We verify the exact concentration and identity of (-)-Epicatechin using high-performance liquid chromatography (HPLC) to confirm our 90% standardization meets specification.
    • Third-Party Lab Tested: Each batch undergoes comprehensive testing by independent laboratories for purity, potency, and contaminants, with certificates of analysis available for verification.
    • Precise 200mg Dosing: Our powder format allows for accurate dosing at the research-supported 200mg daily amount, providing optimal bioavailability for supplements for muscle growth and cardiovascular support.

    Mechanism of Action

    • Myostatin Support: (-)-Epicatechin supports healthy myostatin activity, a protein involved in muscle development regulation, while promoting follistatin expression which naturally balances myostatin function.
    • Nitric Oxide Enhancement: The compound supports endothelial nitric oxide synthase (eNOS) enzyme activity, promoting healthy nitric oxide production that supports vasodilation and healthy blood flow throughout the body.
    • Supports Antioxidant Activity: Functions as a flavanol that supports antioxidant activity by supporting healthy cellular function and muscle recovery processes through balanced oxidative stress response.
    • BDNF Modulation: Supports healthy brain-derived neurotrophic factor (BDNF) expression and neuroplasticity pathways, promoting cognitive function and memory formation through enhanced neuronal communication.

    Overview of the Science

    Research indicates that epicatechin offers notable cognitive benefits through its effects on cerebral blood flow and neuroplasticity. Studies suggest that epicatechin can cross the blood-brain barrier where it promotes nitric oxide production in brain tissue, supporting healthy circulation to neural regions critical for memory formation and executive function [1]. The compound supports BDNF (brain-derived neurotrophic factor) expression, which promotes the growth and maintenance of neurons. Additionally, epicatechin demonstrates neuroprotective properties against oxidative stress, helping to maintain healthy brain aging processes. These cognitive effects make epicatechin particularly valuable for individuals seeking to support mental performance alongside its well-established benefits for muscle development.

    The bioavailability and absorption of epicatechin can be influenced by several factors including timing, food intake, and individual metabolic differences. Research suggests that epicatechin is rapidly absorbed but also quickly metabolized, with peak plasma concentrations typically occurring within 1-2 hours of consumption. For optimal absorption, some studies indicate that taking epicatechin on an empty stomach may enhance uptake, though it can be taken with food to minimize any potential gastric discomfort. The compound's effects on muscle protein synthesis and cardiovascular function appear to be dose-dependent, with consistent daily supplementation providing cumulative benefits over several weeks of use.

    [1] Wang Y, Zhao L, Wang D, et al. Neuroprotective Effects of Epicatechin against Oxidative Stress-Induced [...]: A Systematic Review and Meta-Analysis. J Agric Food Chem. 2016;64(2):475-486.

    Ingredients

    (-)- Epicatechin:

    • 90% Purity Standardization
    • 200mg per serving
    • Natural flavanol extract

    Our 90% purity standardization represents one of the highest concentrations available, requiring advanced extraction techniques to isolate this specific bioactive compound from natural sources. This standardization level ensures consistent dosing and bioavailability, delivering therapeutic amounts that align with research protocols used in clinical studies on muscle growth and energy enhancement.

    (-)-Epicatechin 90% Powder Supplement Facts Panel

  • Lab Testing Results / Certificate of Analysis (COA)

  • Frequently asked questions

    1. How much Nootropics Depot epicatechin powder should I take?

      Our (-)- Epicatechin 90% powder is typically taken at 50-100mg once daily, though you'll need a milligram scale for accurate dosing since this product doesn't include a scoop. The powder can be taken with or without food at any time of day. Most users notice immediate effects, with full benefits developing over 2-3 weeks of consistent use.

    2. Can I take epicatechin with other Nootropics Depot products?

      Yes, our (-)-Epicatechin 90% can be safely combined with other Nootropics Depot products. Since it has flexible dosing timing and can be taken with or without food, it stacks well with most supplements in our catalog. We recommend starting with individual products first to assess your response before combining multiple supplements.

    3. When should I take Nootropics Depot's epicatechin powder?

      Our (-)- Epicatechin 90% powder can be taken at any time of day, with or without food, making it highly flexible for your routine. We recommend taking it once daily for optimal results. While you may notice some immediate effects, full benefits typically develop over 2-3 weeks of consistent use.

    4. Does Nootropics Depot's epicatechin need to be cycled?

      No, our (-)- Epicatechin 90% does not require cycling and can be taken continuously. The compound works through natural pathways that support muscle growth and cardiovascular function without building tolerance. We recommend taking it once daily with or without food for consistent benefits.

    5. Can I stack epicatechin with creatine or protein powder?

      Yes, epicatechin can be safely stacked with creatine or protein powder as they work through different mechanisms to support muscle growth and performance. Our (-)- Epicatechin 90% supports muscle development through myostatin regulation, while creatine enhances energy production and protein provides building blocks for muscle tissue. This combination can be particularly effective for those looking to maximize their fitness and muscle-building goals.

    6. How long before I see results from epicatechin powder?

      Epicatechin can produce immediate effects, with full results typically developing over 2-3 weeks of consistent use. Our 90% epicatechin powder supports muscle growth, cardiovascular function, and cognitive performance through enhanced blood flow and myostatin regulation. For best results, take it daily as part of your regular supplement routine.

    7. Why is Nootropics Depot's epicatechin 90% standardized?

      Our (-)- Epicatechin is standardized to 90% purity to deliver consistent, potent levels of this bioactive flavanol in every dose. We found most epicatechin products on the market offered low concentrations with unclear standardizations, so we developed this highly concentrated extract to ensure reliable potency. This 90% standardization provides the therapeutic levels needed to support muscle growth, cardiovascular function, and cognitive performance.

    8. What is epicatechin?

      Epicatechin is a bioactive flavanol naturally found in green tea and dark chocolate that supports muscle growth, cardiovascular health, and cognitive function. Our (-)- Epicatechin 90% powder delivers this compound at 90% purity, which supports muscle development through myostatin regulation while promoting healthy blood flow to both muscles and the brain. Research indicates epicatechin can cross the blood-brain barrier to enhance memory and executive function through improved cerebral circulation and BDNF expression.

Trust Through Transparency

Your health matters, which is why we only use the best 3rd party ISO accredited labs and cGMP certified and FDA registered facilities right here in the USA

Learn more

Frequently Bought Together

Please choose options for all selected products

(-)- Epicatechin 90% Powder

(-)- Epicatechin 90% Powder

$29.99 - $64.99