About Ginkgo biloba Extract Tablets

Our Ginkgo Biloba extract delivers standardized levels of bioactive compounds from one of the world's oldest tree species. Each tablet provides minimum 2% bilobalide and 10% kaempferol glycosides, supporting cognitive function, cardiovascular function, and healthy oxidative balance.

Our Ginkgo Biloba Story

Most ginkgo biloba extracts lack meaningful standardization of the compounds that drive their benefits. Consumers deserve transparency about what they're actually getting in their ginkgo supplement, particularly the key bioactive constituents that research has identified as responsible for cognitive and cardiovascular support.

We focus on rigorous standardization of bilobalide and kaempferol glycosides, two compounds that work through distinct but complementary pathways. Bilobalide supports healthy neurological function and ATP synthesis while kaempferol modulates cellular health through antioxidant activity. Instead of generic extracts with inconsistent potency, we established strict minimum thresholds that ensure each tablet delivers reliable levels of these research-backed compounds, giving you the ginkgo biloba supplement that traditional practices and modern science both support.

Benefits

• Supports Healthy Cognitive Function: Ginkgo biloba supports memory and mental clarity through its standardized bilobalide content, which supports healthy neurological function and ATP synthesis in brain cells.
• Promotes Healthy Circulation: The extract supports blood flow throughout the body, particularly to the brain and extremities, helping deliver oxygen and nutrients to tissues.
• Supports Healthy Neuronal Function: Bilobalide interacts with key pathways that promote neuronal health and support cellular resilience, supporting overall brain function and communication between nerve cells.
• Supports a Healthy Inflammatory Response: Kaempferol modulates the MAPK pathway and cellular signaling processes, helping maintain healthy inflammatory responses at the cellular level.

Ginkgo's compounds work together to support overall vitality. Research shows that the flavonoid content, particularly kaempferol glycosides, works alongside bilobalide to support the body's natural antioxidant defenses and support cellular energy production, making this extract valuable for maintaining mental sharpness and physical well-being as you age.

Quality and Standardization

• Standardized Constituent Levels: Our extract is standardized to deliver minimum 2% bilobalide and 10% kaempferol glycosides, ensuring consistent potency and reliable levels of the most bioactive compounds found in ginkgo research.
• Third-Party Testing Verification: Each batch undergoes comprehensive laboratory analysis to verify identity, purity, and potency, confirming our standardization claims and ensuring the absence of contaminants or adulterants.
• Optimized Extraction Process: We utilize a specialized extraction method that concentrates the terpenoids and flavonoid glycosides while maintaining the natural ratio of bioactive compounds found in traditional ginkgo preparations.
• Quality Source Material: Our ginkgo leaves are carefully selected from mature trees and processed under controlled conditions to preserve the delicate balance of compounds that support healthy oxidative balance and brain health.

Mechanism of Action

• Bilobalide Neuroprotection: Bilobalide, a sesquiterpene trilactone, supports healthy neurological function by interacting with cellular pathways that promote ATP synthesis and help maintain a healthy inflammatory response in brain tissue.
• Kaempferol Cellular Signaling: Kaempferol modulates the MAPK pathway, a critical cellular signaling network that influences cellular function and supports healthy inflammatory responses, promoting overall cellular function.
• Flavonoid Glycoside Activity: The standardized kaempferol glycosides work synergistically with other flavonoid compounds to support healthy oxidative balance and promote healthy cellular defense mechanisms.
• Terpenoid-Flavonoid Synergy: The combination of bilobalide terpenoids and kaempferol flavonoids creates a dual-pathway approach that supports both cognitive and cardiovascular pathways through complementary molecular mechanisms.

Overview of the Science

Ginkgo biloba extract has been extensively studied for its potential cognitive and cardiovascular benefits, with research focusing on its unique bioactive compounds. Multiple clinical trials have investigated ginkgo's effects on memory and mental function, with studies showing that ginkgo supports healthy cognitive function in healthy adults [1][5]. Research has also examined ginkgo's impact on circulation, with studies demonstrating that ginkgo supports healthy coronary blood flow through enhanced nitric oxide production and reduced endothelin-1 levels [2]. The extract's flavonoids and terpenoids appear to work synergistically to support healthy inflammatory responses and cellular protection against oxidative stress [3][4].

Recent investigations have explored ginkgo's neuroprotective mechanisms, particularly its ability to inhibit amyloid-beta aggregation and reduce caspase-3 activation, which contributes to its cognitive support properties [6]. Studies suggest that ginkgo extract supports healthy oxygen free radical levels while promoting cardiac function during stress conditions [4]. The standardized extract's consistent delivery of bilobalide and kaempferol glycosides ensures reliable access to the compounds most frequently studied in clinical research, making it a valuable addition to longevity and cognitive health protocols.

[1] Schneider LS, DeKosky ST, Farlow MR, Tariot PN, Hoerr R, Kieser M. A randomized, double-blind, placebo-controlled trial of two doses of ginkgo biloba extract in [...] of the [...] type. Curr Alzheimer Res. 2005;2(5):541-551.

[2] Wu YZ, Li SQ, Zu XG, Du J, Wang FF. Ginkgo biloba extract improves coronary artery circulation in patients with coronary artery disease: contribution of plasma nitric oxide and endothelin-1. Phytother Res. 2008;22(6):734-739.

[3] Ginkgolide B reduces inflammatory protein expression in oxidized low-density lipoprotein-stimulated human vascular endothelial cells. Atherosclerosis. 2011;217(2):431-437.

[4] Shen J, Wang J, Zhao B, Hou J, Gao T, Xin W. Effects of EGb 761 on nitric oxide and oxygen free radicals, myocardial damage and arrhythmia in ischemia-reperfusion injury in vivo. Biochim Biophys Acta. 1998;1406(3):228-236.

[5] Kanowski S, Herrmann WM, Stephan K, Wierich W, Hoerr R. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative [...] of the [...] type or multi-infarct [...]. Pharmacopsychiatry. 1996;29(2):47-56.

[6] Luo Y, Smith JV, Paramasivam V, Burdick A, Curry KJ, Buford JP, Khan I, Netzer WJ, Xu H, Butko P. Inhibition of amyloid-beta aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761. Proc Natl Acad Sci USA. 2002;99(19):12197-12202.

Ingredients

Ginkgo Biloba Extract:

• Ginkgo biloba leaf extract
• Standardized to minimum 10% kaempferol glycosides, 2% bilobalide
• 120mg per tablet

This dual standardization ensures therapeutic levels of ginkgo's most researched active compounds. The 10% kaempferol glycoside content provides robust anti oxidative stress support, while the 2% bilobalide specification delivers the neuroprotective sesquiterpenes that research shows are essential for cognitive benefits. Many ginkgo products only standardize for one compound or use lower percentages, but our extract meets the levels used in successful clinical studies.