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Hesperidin is a major flavonoid commonly found in citrus fruits and some vegetables. Hesperidin was first isolated in 1828 from the inner white layer of citrus peels and is the food bound form of hesperitin, a bioflavonoid that mediates most benefits of hesperidin including cardiovascular and neuroprotective benefits. It’s important to note the difference between hesperitin and Hesperidin is that Hesperidin converts into hesperitin in the body. For a while, hesperitin was incorrectly labeled as Vitamin C as it is found in citrus products and particularly concentrated in orange peels. Hesperidin has become a popular subject of recent research as there are believed to be a wide range of Hesperidin benefits.
Although Hesperidin’s most well known benefits are supporting blood flow and balanced oxidation levels, some research indicates that there may be other Hesperidin benefits to take advantage of. Interestingly, both a clinical trial and an animal study found that metabolic function and hesperidin weight loss benefits were supported by Hesperidin in the experimental groups. Results found that Hesperidin interacted with AMPK and PPAR signaling, which are believed to support processes involved in weight loss.
Additional evidence even suggests Hesperidin helps support balanced inflammation levels and the overall immune system. A small human trial concluded that Hesperidin may carry some neuroprotective properties as subjects reportedly showed enhanced cognitive function. Some researchers believe this effect may be related to Hesperidin’s impact on inflammation levels. Further research is still out to determine these results with more certainty. While preliminary findings indicate that these benefits may be a byproduct of Hesperidin’s impact on inflammation, blood flow, and oxidative stress, the benefits in these categories were still notable.
Check out our recommended Hesperidin stacks, that help further amplify Hesperidin benefits!
Balanced Oxidation Levels Stack: Hesperidin with Salidrosol Sublingual Solution
This combination is a quick acting and targeted approach to balancing oxidation levels. You may also reap additional benefits to inflammation levels and cognitive function.*
Immune Function Stack: Hesperidin with Immune Defense
Add Hesperidin to our comprehensive Immune Defense formula for added benefits to immune system function.*
Blood Flow Stack: Hesperidin with L-Citrulline DL Malate
Hesperidin paired with L-Citrulline DL Malate is a two pronged approach to supporting overall cardiovascular function with additional benefits to metabolic function.*
As a dietary supplement, take 500mg of Hesperidin powder once daily.
To gain more insight read the Hesperidin reviews and experiences below.
Nootropics Depot offers 30g and 60g jars of high quality Hesperidin powder. Nootropics Depot's Hesperidin powder has been lab-tested and verified for both product purity and identity.
| *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. |
I use this mostly as a gut health supplement, but it definitely has cognitive boosting qualities as well. It's a unique prebiotic in that research shows that it activates gut associated lymphatic tissues to coat gut bacteria with IgA, which is an important process in gut health. It's one of the few prebiotics that I tolerate.
I use this in combo with immune support whenever I feel unwell and I feel better within 1-2 days
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