Tribugen is our next generation version of our popular Tribulus terrestris extract. When we created our first Tribulus terrestris extract, we wanted to achieve the perfect balance of effects. Strongly motivating and stimulating, while still remaining smooth and mood boosting. This Tribulus terrestris extract turned out to be a big hit but some people still expressed an interest in an even stronger Tribulus terrestris extract! Our first instinct was to beta-test the strongest possible Tribulus terrestris extracts but they did not feel very nice to us. Strong yes, but also incredibly edgy. So, how could we make Tribulus terrestris stronger, while not sacrificing smoothness and balance? It turns out that the answer was not to focus on a stronger Tribulus terrestris extract, instead we needed to start stacking with Tribulus terrestris with other extracts to bring out its best properties!

It’s finally here, ErinaMAX, our liquid culture lion’s mane mycelium standardized to 0.5% erinacine A! The mycelium of the lion’s mane mushroom can generate a very unique nerve growth factor (NGF) boosting compound called erinacine A.* To generate significant levels of erinacine A you need giant bioreactors in which you can grow lion’s mane mycelium to exacting standards in a liquid growth medium.* The main appeal of erinacine A is that it can boost the synthesis of NGF, a compound which is a major driver of neuroplasticity and nerve regeneration.* By enhancing the level of NGF with erinacine A, we can dial in cognitive function, mood, focus and neuroprotection while also helping with pain management, specifically when it comes to nerve related pain.* It’s no wonder that erinacine A containing lion’s mane mycelium was always viewed as one of the “holy grail” mushroom supplements. Despite it being so sought after, we believe that with this release we have likely put out the only real erinacine A containing lion’s mane mycelium on the market!

Have you always been interested in the mood boosting effects of licorice, but shied away from licorice extracts in the past due to the potential for less than desirable effects? Then isoliquiritigenin is what you’ve been looking for! Traditional licorice extracts contain many different compounds, amongst which is glycyrrhizin, which produces undesirable cardiovascular effects. There are also a variety of mood boosting compounds in licorice root, but one of the most potent mood boosting compounds is isoliquiritigenin. This produces a very comprehensive mood boosting effect, which is primarily being produced by its GABA-A and GABA-B modulating properties.* These GABAergic effects are also accompanied by monoamine oxidase inhibition, NMDA antagonism and direct affinity towards dopamine D3 receptors. The collective effect is a very unique relaxing GABAergic profile, which is seemingly entirely devoid of lethargy.* This makes it an ideal candidate for dialing in a relaxed mind whilst still keeping focus and drive high throughout the day!*

Lignosus rhinoceros, better known as the tiger milk mushroom, is an incredibly rare mushroom that up until recently has been impossible to cultivate. We connected with a very high tech cultivator of tiger milk mushrooms recently who cultivates the highest quality tiger milk mushroom sclerotium product currently available, and we are the first to offer it in the United States! One of the reasons tiger milk mushroom has started to become so sought after in the functional mushroom space, is due to the plethora of research that has come out recently showing that it can enhance neuroplasticity in a similar manner to lion’s mane mushroom. Furthermore, tiger milk mushroom also significantly enhances respiratory function, which is a very unique effect amongst mushroom supplements. Combine this with the prominent immune boosting and inflammation regulating effects, and it is clear to see why this is the next big mushroom supplement!

When it comes to brain function and energy production, B vitamins are incredibly important! Without them, a lot of neurotransmitters couldn’t be synthesized, myelin sheaths would degrade, and food wouldn’t turn into usable energy as readily. However, B-vitamins are all water soluble, and because of this, they are not stored in the body like other fat soluble vitamins are. This means that B-vitamins need to be constantly replenished. This happens via our diet, but deficiencies can occur over time. This can have negative impacts on cognitive function, mood, focus, skin health and even metabolic function. Most B-complex products on the market use forms of B-vitamins that do not absorb well or simply aren’t very active. We included only highly absorbable and active forms of B-vitamins in Infini-B! Secondly, B-vitamins are often either dosed way too low or way too high. We sought to find the perfect dosing level of these B-vitamins, verifying good effects in multiple rounds of beta-testing. The end result is one of the best B-vitamin complexes ever created!

Over the years, the concept of microdosing has really taken off; yet for the average person, it is quite an inaccessible concept to partake in (for now). Although the legislative environment is changing, wide spread microdosing accessibility is still a ways off. Luckily, we had the foresight many years ago to look towards one of the most famous natural nootropics, Bacopa monnieri. It contains the precursor for a fantastic molecule called ebelin lactone, which just so happens to be a positive allosteric modulator of one of the main receptor targets of microdosing: 5-HT2A! Through a patented extraction and processing method, we were able to, for the first time ever, concentrate massive amounts of ebelin lactone! This has never been done before, so you are among the first to try out this unique molecule! Ebelin lactone is perhaps one of the only high affinity natural 5-HT2A positive allosteric modulators. The effects you can expect from Cognance are a distinct mood boosting effect, backed up by increases in overall cognitive function, focus, and even creativity!

Pregnenolone is a natural substance that can help improve your mood, confidence, vitality, and muscle strength. It works by enhancing the synthesis of androgens, which are important for these effects. The recommended dose is very low at 5 mg to avoid potential negative effects at higher doses. In addition to these benefits, pregnenolone can also enhance brain function and memory by activating certain receptors in the brain. Overall, pregnenolone is a promising supplement for those looking to improve their physical and mental well-being. When you take it, you may see an increase in many different hormones. But the amount you take is important because taking too much can stop the production of some hormones while still making others. This happens in a specific order, with certain hormones being shut off first. However, progesterone production continues even if other hormone production is reduced. This is why our product is dosed very low at 5 mg.

Tribulus terrestris has fascinating effects on different bodily systems, such as enhancing DHT production, which leads to greater confidence and energizing effects. Additionally, its beta-carboline content has a mild MAO-i effect, boosting energy, focus and mood, making it a winner as a nootropic. Moreover, Tribulus terrestris enhances blood flow, which has a major effect on libido. Overall, Tribulus terrestris is a powerful herb with a lot of potential benefits for those looking to boost their energy, confidence, and reproductive health. So, why choose our Tribulus terrestris? We selected this extract based on both rigorous analytical testing, but also bioassaying! This is a fancy way of saying we actually tried out a bunch of different Tribulus extracts on ourselves to see which one produced the best results. We discovered that a lot of Tribulus extracts can induce a very unpleasant sense of agitation. After a while, we found an extract that struck a perfect balance. It gave us tons of confidence, but didn’t push us into a state of agitation.

Vignatex is a natural supplement made from mung beans and passionflower extracts. It inhibits an enzyme called MAO-B, which leads to an increase in certain neurotransmitters, resulting in a clean stimulating effect and an uplifting mood boost. Taken alone, this effect can be somewhat unbalanced, but when paired with passionflower, the effects are smoothed out slightly, leading to a very unique flow state like stimulating effect. Passionflower helps temper the stimulating effects of mung bean and provides a mild calming effect, making Vignatex smooth and easy to attain focus. While the mood elevating and focus enhancing effects are highlights of Vignatex, the pain management effects are also very unique and prominent. This positions Vignatex as one of the more unique pain management supplements we offer, as it helps give you back the energy that pain can rob you from, while simultaneously promoting pain management!

We were on a quest to create a coffee-like caffeine stack that would lift our moods. After some snooping around, we found a compound in coffee called trigonelline that made us feel all kinds of interesting things. We hunted high and low for it until we stumbled upon fenugreek, which was loaded with it! We tried out some fenugreek beta-testing samples and boom - we were hooked on its mood-boosting powers. It boosted our drive and self-assurance, thanks to the capacity of trigonelline to increase the release of a certain neurotransmitter associated with pleasure and reward. Fenugreek reminded us of Tribulus terrestris, which we saw as a Jekyll and Hyde situation. Fenugreek was the fun-loving Jekyll, while Tribulus was the intense and brooding Hyde. Fenugreek is perfect for those who want the feel-good vibes without the aggression. Fenugreek also pumps up our hormone levels that play a role in muscle building, which is perfect when paired with other hormone boosters. Its trigonelline content also helps us metabolize glucose and fat, which makes it an excellent fitness-promoting ingredient. Fenugreek has got it all - it's like a one-stop-shop for mood and fitness boosting!

Have you ever thought that coriander could have superpowers? Well, it does! We were also surprised when we discovered the powerful compounds in this little seed. After testing the supercritical CO2 extract, we were blown away by its effects. In just 15-30 minutes, we felt a warm and relaxing wave that melted away all our stress. Linalool has very pronounced effects on the GABAergic system, and because our supercritical CO2 coriander extract is very high in linalool, this means it possesses prominent GABAergic effects. This is where the majority of the mental and physical relaxation effects come from. These effects are further potentiated by linalools ability to block NMDA receptors and the serotonin transporter, while also interacting with glycinergic, adrenergic and adenosinergic signaling. By hitting these targets, our coriander extract produces a wonderful and powerful relaxing effect that has quickly become a favorite around the office! Not only do these neurological mechanisms aid in relaxation, they also help enhance sleep quality.

One of the most unique effects associated with quercetin, is its ability to act as a zinc ionophore. To pull a shameless Leslie Knope, Webster’s dictionary defines an ionophore as:

“A compound that facilitates transmission of an ion (as of calcium) across a lipid barrier (as in a cell membrane) by combining with the ion or by increasing the permeability of the barrier to it”

Quercetin produces this interesting effect, specifically for zinc. To break this effect down a little bit more, let’s think about how compounds can get into a cell. This either happens through passive diffusion or through active transport. Passive diffusion is a tough trick to pull off for most compounds and for active transport to take place, you need to get lucky with having a specific transporter for your target compound. Zinc certainly has specific active transporters it can use, however, it could still use a helping hand. This is where inophore’s come in. We can think of them sort of as chaperones, carrying zinc straight into cells where it can exert its benefits.

NAD+ plays a major role in cellular energy production, metabolism, healthy aging, brain health, and even controls aspects of our circadian rhythms! Pretty much every cell in our body relies on NAD+, so enhancing its levels can have very wide ranging benefits. This is especially true as we age, since NAD+ production starts to decline with age, and our NAD+ stores start to become depleted. By adding NADH into your daily routine, you are able to help ease the natural decline and give your body the NAD+ levels it needs, while also boosting your energy levels! During beta-testing, we all instantly noticed how much more energizing NADH can be when compared to other NAD+ supplements like Nicotinamide Riboside. So, if you want to get straight to the point and raise NAD+ levels as quickly as possible, then NADH is going to be a perfect fit for you! Within our beta-testing program, we quickly discovered that the energizing effects of NADH are quite pronounced.* In a similar vein, if you do get noticeable energizing effects from other NAD+ precursors, and want more of it, then NADH would be the perfect fit for you!

If you are looking for a very comprehensive stand alone supplement, astragaloside IV may be it! With a wide range of diverse effects from robust neuroprotection to longevity effects, there is something here for everyone!* Astragaloside IV is one of the most powerful compounds contained in Astragalus membranaceus, a unique herb native to Mongolia. Since it is one of the most potent compounds in Astragalus membranaceus and given that our extract is standardized to a whopping 50% Astragaloside IV, this may be one of the most effective Astragalus membranaceus extracts currently on the market!* With this in mind, if you have ever been interested in trying out a very high quality Astragalus membranaceus extract, then this is the one for you! Astragaloside IV has neuroprotective benefits, protecting the neurons in the hippocampus by reducing neuroinflammation and neuro oxidation. It also strengthens the blood brain barrier and protects against stress.

Looking for a supplement to ease your joint and gastrointestinal pain? Look no further than casperome boswellia phytosome from Indena! This cutting-edge supplement contains triterpenoic acids from the Boswellia serrata tree, which have potent effects on inflammation and gastrointestinal comfort. Indena goes above and beyond by standardizing their product to include all 11 boswellic acids, not just the usual two. Not only is casperome standardized to a high full spectrum concentration of triterpenoic acids, the triterpenoic acids have also been incorporated into a phytosome. This helps significantly enhance the absorption of the triterpenoic acids which then helps produce potent and consistent effects! Furthermore, casperome has also been the subject of a whopping 10 human studies, which have shown time and time again just how effective casperome is for promoting joint, gastrointestinal and musculoskeletal comfort! Plus, with a history of use in ancient perfumery and incense, casperome has stood the test of time as a highly praised commodity. So why not give it a try and sniff out the benefits for yourself?

One of myrrh’s main claims to fame are its incredible pain management effects! These effects can be traced back to the furanodienes. Specifically two furanodienes, furaneudesma-1,3-diene and curzerene, which interact with central opioid receptors in the brain. By activating these central opioid receptors, they can help dampen incoming nociceptive signals, which our brain interprets as pain. Additionally, the furanodienes also help dampen inflammation. Together with the central opioid effects, this produces a very comprehensive pain management effect. This effect extends to all areas of pain, and can even help promote joint comfort! Myrrh also possesses some unique antimicrobial properties. This is probably also part of the reason it was used during the embalming of mummies! This could have some beneficial effects in the urinary tract according to a study on myrrh extract. In a somewhat similar vein, myrrh also appears to offer gastroprotective effects and skin protective properties. Overall, our myrrh extract offers a fairly wide array of benefits!

Berberine is a supplement that activates a protein called AMPK, which helps with cellular energy and glucose processing. It can mimic the effects of fasting on metabolism, leading to benefits even when fasting isn't possible. Berberine is well-known for its ability to support insulin secretion and glucose absorption, making it a popular supplement for metabolic health. Berberine also helps dial in glucose processing, and this is one effect berberine is most famous for. It does this via a variety of mechanisms, with one of the main mechanisms being AMPK activation. That being said, berberine also has a few other tricks up its sleeve. For example, it can help support insulin secretions by promoting the function of beta-cells. In addition to this unique effect, berberine also appears to subtly affect the absorption of glucose from food. Berberine is by far the most effective supplement for promoting metabolic health, while also helping to regulate glucose levels. In addition to these fantastic effects on metabolic health, berberine also has distinct nootropic effects, helping to dial in concentration, memory and mood! All in all, it is quite clear why berberine is such a renowned metabolic health supplement!