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Oleamide Capsules | 100mg

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Oleamide Capsules | 100mg
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Description

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What are Oleamide Capsules?

Oleamide, also known as Cerebrodiene, is an organic compound and the primary amide derived from oleic acid ODA (octadecanoamide). Oleic Acid is an omega-9 fatty acid from olive oil. Oleamide is colorless and has a waxy solid texture. Oleamide was first isolated from the spinal fluid of sleep-deprived cats. Sometimes Oleamide is classified as a fatty acid primary amide (FAPA) and occurs naturally in animals and accumulates in the cerebrospinal fluid when the body is experiencing sleep deprivation. The natural occurrence of Oleamide in human serum was first reported in 1989.

Oleamide Uses and Benefits

Studies have shown that Oleamide may have the following benefits:

  • May help support healthy sleeping habits
  • May help promote cognitive function
  • May help support brain health

History of Use for Oleamide

Oleamide is a natural metabolite of Oleic acid and has been used in traditional Chinese practices for sleep support. The first use of Oleamide in Traditional Chinese practices started with the Jujube fruit where its usage dates as far back as 2500 years. This later sparked research in which it was found that Oleamide naturally occurs in Jujube plants. Further research has shown that Oleamide appears to be synthesized in humans from ammonia and oleic acid.

Additionally, it has been determined that Oleamide is structurally similar to anandamide. Anecdotal reports suggest that their Oleamide experiences improved their sleep habits.

So far it’s seen that Oleamide has interactions with multiple neurotransmitter systems. Oleamide interacts with the brain’s GABA receptors which is helpful for promoting relaxation. It’s also been discovered that oleamide can bind to the CB1 receptor (cannabinoid 1 receptor). Some research suggests that Oleamide effects can promote healthy levels of neuroinflammation by acting on the CB2 (cannabinoid 2 receptor) in high concentrations. Thus suggesting that this compound has potential to promote cellular health and promote healthy stress levels.

Studies have shown serotoninergic effects of Oleamide. It makes the 5-HT2A serotonin receptors more sensitive without necessarily influencing the normal signaling process. It also seems to extend the enhanced sensitivity to 5-HT1A and 5-HT2C receptors with no effect on the 5-HT3 receptors and has no effect on serotonin binding to the 5-HT receptors.

Interestingly, Oleamide binds to the 5HT7 receptors and acts as an inhibitor on the 5-HT7 receptor. It acts as agonist on the receptor when no serotonin is present and produces serotonin like effects at a lower intensity.

There is continuous research being conducted to discover more about Oleamide’s influence and on sleep and other Oleamide effects.

How To Take Oleamide Capsules

As a dietary supplement, take one 100mg Oleamide capsule 1-2 times daily.

Oleamide Reviews

To gain more insight, read the Oleamide experiences and reviews below.

Where to Buy Oleamide Capsules

Nootropics Depot offers a 60 count or 120 count jar of high quality Oleamide capsules. Nootropics Depot's Oleamide has been lab tested for product purity and identity.

Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

2 Reviews

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  • AwakeinLBC - 26th Jul 2020

    5
    Pretty powerful and wide ranging effects

    Oleamide is a multi mode serotonin modulator for sure. It boosts serotonin metabolism in subtle but concrete ways. It’s also a choline booster by binding to enzyme that breaks down acetylcholine and it is an anti neuroi inflammatory reducing LPS To IL-6 inflammation. Did a lot of research on it after reading ND’s description. Reminded me of trintellix a novel multi mode action SSRI that is for major depressive disorder but also independently is shown to boost cognition over time. It also antagonizes 5htp7 and agonizes 5hpt1A among other receptors and drives pyramidal neurotransmitter activity across the board. This is a natural version of that in some respects.

    One downside is if you take two at a time, it was depressive for me. If you take it apart during the day and night, it works great. Everybody’s epigenetics is different so use accordingly.

  • Kevin Townsend - 14th Apr 2020

    5
    dreams

    I rarely had dreams before. Now I get them much more often. I get a deeper, more restful sleep too.

2 Reviews

  • AwakeinLBC - 26th Jul 2020

    5
    Pretty powerful and wide ranging effects

    Oleamide is a multi mode serotonin modulator for sure. It boosts serotonin metabolism in subtle but concrete ways. It’s also a choline booster by binding to enzyme that breaks down acetylcholine and it is an anti neuroi inflammatory reducing LPS To IL-6 inflammation. Did a lot of research on it after reading ND’s description. Reminded me of trintellix a novel multi mode action SSRI that is for major depressive disorder but also independently is shown to boost cognition over time. It also antagonizes 5htp7 and agonizes 5hpt1A among other receptors and drives pyramidal neurotransmitter activity across the board. This is a natural version of that in some respects. One downside is if you take two at a time, it was depressive for me. If you take it apart during the day and night, it works great. Everybody’s epigenetics is different so use accordingly.

  • Kevin Townsend - 14th Apr 2020

    5
    dreams

    I rarely had dreams before. Now I get them much more often. I get a deeper, more restful sleep too.