Polygala tenuifolia 20:1 Extract Powder | Yuan Zhi

(52 reviews) Write a Review
Add to Cart




SKU:ND1137A ,Width: ,Height: ,Depth:


Polygala tenuifolia (Yuan Zhi) 20:1 Extract
30g or 60g
300 Servings or 600 Servings
As a dietary supplement, take 100mg of Polygala tenuifolia Extract 1-3 times daily.
Store in a cool and dry place. Keep away from direct sunlight and heat.
Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.
Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases. These statements have not been evaluated by the Food and Drug Administration.
This product does not include a scoop. Transfer scoops are not an accurate form of measurement. A milligram scale is needed to accurately measure this product.

Frequently Bought Together:

Polygala tenuifolia 20:1 Extract Powder | Yuan Zhi
Inc. Tax
Ex. Tax


Polygala Tenuifolia Powder

What is Polygala tenuifolia?

Polygala tenuifolia is a perennial purple flowering plant that grows in semi shade or no shade environments and has a tendency to grow in moist soil. Polygala tenuifolia is native to Asia and can be found in grasslands, mountain slopes, prairies, and shrub forests. Polygala tenuifolia root has widespread use in Traditional Chinese practices and is traditionally referred to as Yuan Zhi or Chinese Senega and is believed to promote cognitive function when ingested orally. Anecdotally, people report that the calming and stimulating effects of Yuan Zhi help promote focus without feeling overstimulated or experiencing jitters like large amounts of caffeine. Modern research has found that Yuan Zhi’s adaptogen-like properties may promote healthy stress levels and optimize cognitive function but more research is needed to solidify these findings.

Polygala Yuan Zhi Benefits and Uses

    • May help promote cognitive function
    • May help support feelings of well being
    • May help promote healthy stress levels
    • May help support respiratory health
    • May help promote neuroplasticity
    • May help support sleep quality

Polygala and The Brain

Polygala tenuifolia is quite unique since unlike most plant extracts which have only one or two primary effects, Polygala has a very wide range of effects. Most Polygala users report feeling a calming yet stimulating sensation when taking a Polygala supplement. This is interesting since this type of feeling is typically only achievable with a combination of supplements, such as a simple stack of caffeine and l theanine. Although it is quite stimulating, Polygala tenuifolia may also help promote sleep quality. Typically, the calming effects of Polygala seem to outlast the stimulating effects. The sleep promoting effects are believed to be associated with its tenuifolin content, a bioactive compound found in Polygala tenuifolia root extracts. Human trials also suggest that Polygala tenuifolia may help promote spatial awareness and organization.

Some findings show that Polygala tenuifolia may help support neuroplasticity. Neuroplasticity is the process by which our brains can change, adapt and grow, which is an important process for many cognitive functions as they are dependant on adequate levels of neuroplasticity. This is relevant to memory and memories, as these are believed to be stored by neuron connections that are physically changing. These changes are dependant on neuroplasticity. Two of the biggest regulators for neuroplasticity are nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF). Studies have found that with an increase in either of these regulators, neuroplasticity can be notably boosted. Polygala tenuifolia is believed to increases both levels of BDNF and NGF. By increasing BDNF and NGF levels, Polygala tenuifolia may help promote overall brain health as well as cognitive function.

Polygala Tenuifolia Dosage

As a dietary supplement, take 100mg of Polygala tenuifolia Extract one to three times daily

Polygala Tenuifolia Powder Reviews

For more insight, read the Polygala tenuifolia reviews and experiences below.

Where to Buy Polygala Tenuifolia Powder

Nootropics Depot offers 30g or 60g jars of high quality Polygala tenuifolia20:1 Extract Powder (Dual Water/Ethanol Extraction). Nootropics Depot’s Polygala Tenuifolia powder has been lab-tested and verified for both product purity and identity. 

Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

52 Reviews

View All
  • Bryce Goecks - 15th May 2022

    Polygala has helped me so much.

    Polygala is one of the best nootropics I have tried. It takes a bit of time for the effects to build up (probably two weeks max of thrice a day dosing) but when you finally feel the effects. It is absolutely incredible. I dose 150mg-200mg three times a day. I'll likely lessen the dose soon. In the past 100mg twice a day was effective

  • Steve - 30th Mar 2022

    Polygala ..

    It’s ok ..thought it didn’t last that long maybe a couple of hours ..

52 Reviews

  • Bryce Goecks - 15th May 2022

    Polygala has helped me so much.

    Polygala is one of the best nootropics I have tried. It takes a bit of time for the effects to build up (probably two weeks max of thrice a day dosing) but when you finally feel the effects. It is absolutely incredible. I dose 150mg-200mg three times a day. I'll likely lessen the dose soon. In the past 100mg twice a day was effective

  • Steve - 30th Mar 2022

    Polygala ..

    It’s ok ..thought it didn’t last that long maybe a couple of hours ..

  • Maxime Dube - 1st Aug 2021


    Did exactly what I need it to do. Really happy with the delivery time and quality of product.

  • Shyam - 12th Jul 2021

    Good stuff

    Just trying it out now, been a week or so, seems to give a nice small reliable boost of mood, seems like a better version of 5-HTP and St Johns Wort, It seems to help motivation via mood enchancement, I'll rewrite review after a while, I think it's awesome and cheap, if you respond to it.

  • Patrick Miller - 30th May 2021


    This stuff tops ashwaganda for me. It's almost a little too relaxing, verging on sedating a bit. But sometimes you need a way to relax that hard like after a long day of work.

  • Randyjuice - 28th Apr 2021

    Great mood improvement

    Polygala tenuifolia taken sublingually exerts great positive effects on mood. I take it when I feel stressed or nervous, sometimes up to 7 times a day at 100mg sublingually with no adverse effects. I never noticed any good or bad effects on sleep or cognition in general. The immediate effects on mood are great I haven't taken it long enough to notice the increase in neuroplasticity potentially leading to even better mood improvements.

  • Armando - 16th Mar 2021

    It works, it just takes time.

    I bought this like six months ago, and I'm taking 100mg sublingual every day (with a sip of water - pure polygala powder is abrasive in mouth). In the first month, it did not work at all. After that, I felt relaxed and dissociated, especially after stressful days. I recommend this for brain health overall and stress management.

  • DAVID MCKENZIE - 20th Feb 2021

    surprisingly consistent mood lift

    Any review I give will always start with, ND is one of the few vendors that consistently delivers. this is now a part of my stack pretty regularly. it boosts mood, subtle but noticeable.

  • Thijs - 17th Feb 2021

    Not for me personally

    First of all, I know this is a first class polygala extract. I would love to see this product working for me. I’ve tried everything from different dosages to oral to sublingual but everytime within 24 to 48 hours my GI tract starts to get tight and uncomfortable. If i continue it becomes painfull. The only explanation i have for this is that it is to drying and hot in nature. Great quality as always but it just does not agree with me!

  • Tre - 5th Jan 2021

    Helps massively with winter blues

    Whenever I'm feeling down in the winter this helps significantly

  • Andre Noureux - 31st Dec 2020

    Polygala tenuifolia, the best anti-stress plant extract!

    I have recently bought some Turmeric/Curcumin plant extract powders (CuroWhite and Longvida), and the Nootropics Depot said that that in addition to their anti-inflammatory effects, these powders are supposed to support our moods too. Therefore, it was suggested to stack Polygala tenuifolia extract powder with these Curcumin powders for getting and maintaining a better mood. A couple of years ago, I used Polygala tenuifolia and I noticed some positive effects. Therefore, I ordered another can of Polygala tenuifolia extract powder. While I was reading the most recent comments on the Nootropics Depot Polygala tenuifolia webpage, I noticed that some users suggested to put a small dose of the Polygala tenuifolia powder under the tongue for better absorption. I started to do that (1/8 of a teaspoon before meals), and I immediately noticed a strong effect. Polygala tenuifolia powder helps me to relax more so that I feel less the stress that is generated by so many hassles and problems that we may encounter every day. It does not have a sedative effect, but because of its calming effect, my sleep is more peaceful. Mentally speaking, I get less tired. Therefore, most tasks seems less strenuous. Just put some Polygala tenuifolia powder under your tongue, and you will see the difference!

  • Curtis - 22nd Nov 2020


    I recently purchased polygala for the first time. I had heard reviews about it possibly elevating mood and helping reduce stress. As those are both issues I contend with daily I was excited to see what it was all about. I'm glad I did. Right off the bat I felt ready for the day and my usual concerns about my workday and obligations seemed much lighter than usual. Throughout that first work week, every morning I didn't notice my usual stress and concerns about the upcoming day. Issues that would usually leave me tense and agitated seemed to roll off my back and I simply completed my tasks and moved forward. These seemingly simple little things add up to a big impact in the end. As always I am pleased with the quality from ND. Customer service and fast shipping are always first rate. Throw an effective new nootropic on top of that and you once again have a very happy customer.

  • Silviu Cocosila - 11th Sep 2020

    This Herb is the Shit

    Started taking Polygala in Capsule form and haven't noticed much of a difference, hard to notice small improvements when you anxiousness and low mood keep coming back. Then I've read a few reviews of people taking it sublingually, tried it and oh boy oh boy oh boy. The first time taking it subliminally, i particularly felt really anxious and down and within less than 1 minute it felt like the divine hand came down grabbed all the negativity and replaced it with serenity and a strong not giving a fuck feeling. For somebody that gives too many fucks about every little stupid thing, that felt like i went to heaven. On the other hand mom tried it and she says nothing happened to her so idk, try it for yourself

  • Logan H - 26th Jul 2020

    Over A Month In

    I've been taking this for over a month now. The acute effects are amazing, but it truly does build up in your system. Polygala has become the cornerstone of my stack. I hear people say they've given up on nootropics, and I was almost to that point before I found Polygala. Polygala work great by itself, but it has synergy with so many other supplements that didn't seem to work before. Despite all the craziness going on in this world, I can honestly say my mental state has never been better and I give credit to ND and Polygala. Protips: Best taken sublingual. 100mg is a good starting point but 200-250mg is where this really shines for me.

  • Tessa - 13th Jul 2020

    This works!

    I'm usually not the type that writes reviews, but I would like to make an expectation for once. This stuff really works! I have tried many supplements for mood and anxiousness, but none have worked like this one. It took about a week to kick in but my stress levels are way down. All my worries and concerns seem so much more manageable. It gave me the ability back to put things in perspective and not feel overwhelmed. I would highly recommend you give this a shot…

  • Unknown - 9th Jul 2020

    Polygala Tenuifolia - powder

    Another high quality product from ND. I ordered this because they ran out of the caps and although I find the caps more convenient and the powder can be a little difficult to work with, it is easier to dose at different levels and to easier to use sublingually. As a substance I personally find polygala tenuifolia to be a game changer. It has helped relieve negative thoughts and in combination with some of the other supplements I take it seems to give some mental 'space' to be able to 'observe' in a more mindful and objective way thus helping recognise and mitigate negative thought patterns. It does seem quite cholinergic so additional dietary intake or supplementation may need to be considered. I don't think it's necessarily the right fit for everyone but for me it has made a huge difference.

  • Robert Jones - 9th Jul 2020

    Polygala Tenuifolia

    Love this stuff! For me, Polygala, taken sublingually, is more effective for sleep than any other nootropic I have tried.

  • Adam - 2nd Jul 2020


    After researching about Polygala Tenuifolia, it sounded like it was just what I needed. I looked all over the net to try to find a good quality extract powder but all I could find was the whole roots or a basic powder until I discovered Nootropics Depot! This is exactly what I needed and it is a great price also. It is potent and you don't need much. I agree with others, it seems to take around 5-7 days before you notice it working but I am starting to feel better than I have in a long time. Please don't stop selling this, you are the only one to offer such a potent and clean Polygala extract. I highly recommend this product!

  • Logan - 4th Jun 2020

    Best Nootropic I've Tried

    It's only been five days, but WOW. This has worked wonders for me. I can feel again, music sound better, libido is back, it sounds crazy but polygala made me feel human again. Hopefully these effects are here to stay! Stacks really well with cordyceps for energy and motivation.

  • Cooper Beaman - 21st Apr 2020

    Sublingual vs Oral dosing was a game changer

    If you take 25-30 mg sublingually (5-10 min) 3-4 times daily, I'm betting the effects you experience will be more aligned with your expectations especially after one week of use. Initially, I made the mistake of dosing orally (~50mg) which just made my heart race 20-30 mins later and gave me a bit of a dissociated mental feeling (not what I was going for). Perhaps, the Polygala getting metabolized first after oral administration results in the less desirable effects; however, when administered sublingually, this first pass metabolism is circumvented, allowing for the more desirable effects?

Customers Also Viewed