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Sarcosine Tablets (Chewable) | 1000mg

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SKU:ND1228A ,Width: ,Height: ,Depth:

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SKU:
ND1228A
ACTIVE INGREDIENT:
Sarcosine
ITEM TYPE:
Tablets
QUANTITY PER BOTTLE:
60ct. or 120ct.
SERVINGS PER BOTTLE:
60 Servings or 120 Servings
SUGGESTED USE:
As a dietary supplement, take one 1000mg Sarcosine tablet 1-2 times daily. For milder effects, break tablet in half.
STORAGE:
Store in a cool and dry place. Keep away from direct sunlight and heat.
WARNING:
Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.
DISCLAIMER:
Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases. These statements have not been evaluated by the Food and Drug Administration.

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Sarcosine Tablets (Chewable) | 1000mg
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Description

What is Sarcosine?

Sarcosine is also known as N-Methylglycine and Methylglycine. Sarcosine is synthesized from the glycine N-Methyltransferase (GMNT) enzyme which utilizes a methyl group from S-Adenosyl methionine and donates it to glycine. This process creates Sarcosine and S-adenosylhomocysteine.

Sarcosine shares properties with glycine and D-serine but its effects are weaker. However, sarcosine is more reliably absorbed by the body than D-serine so a smaller more practical dose of sarcosine would achieve the same effects compared to glycine or D-serine. Sarcosine metabolism is achieved through pipecolic acid oxidase (PIPOX) or sarcosine dehydrogenase (SARDH) enzymes. PIPOX and SARDH convert sarcosine into glycine.

Sarcosine Benefits and Uses

    • May help promote feelings of well being
    • May help support cognitive function
    • May help pain management support
    • May help support healthy stress levels

Sarcosine Interactions with Glycine

Sarcosine has binding capability to NMDA (N-Methyl-D-aspartate) receptors. Research has found that Sarcosine seems to promote feelings of well being and support cognition by enhancing NMDA receptor signalling via inhibiting one of the major glycine transporters.

Glycine transport inhibitors such as Sarcosine block the uptake of glycine, leaving more glycine present in the synapse. As a result, NMDA receptor signalling is notably enhanced. GlyT1 and GlyT2 are two of the main glycine transporters. Sarcosine targets the GlyT1 transporter which is the more prominent transporter expressed on glial cells. GlyT1 has been observed to be more involved with NMDA signalling than GlyT2. GlyT1 inhibitors such as Sarcosine have also been observed to have a positive effect on cognition but further research is needed to gain a firm conclusion.

While there is still research that needs to be done to determine all the beneficial effects of taking a sarcosine supplement, there are a few isolated human studies that had interesting findings. In one human study on Sarcosine, it was found that subjects self reported increased motivation and less irritable mood when supplementing with 1g-2g of sarcosine powder.

Sarcosine Dosage for Tabets

As a dietary supplement, take one 1000mg Sarcosine tablet 1-2 times daily. For milder effects, break tablet in half. 

Sarcosine Reviews

To Learn more about Sarcosine, see the reviews for our Sarcosine Tablets below. 

Where to Buy Sarcosine Tablets (Chewable)

Nootropics Depot offers 60 count or 120ct. jars of Sarcosine Tablets (Chewable). Nootropics Depot's Sarcosine has been lab-tested and verified for both product purity and identity.

Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

3 Reviews

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  • Undisclosed - 12th Feb 2021

    5
    It worked for me

    I feel this has smoothened out a lot of friction in my mind and given me more control over my thoughts. I used to frequently overthink myself into headaches over the smallest things but that just hasn't happened since. Absolutely not a change I was expecting and something I was cautiously optimistic about, but it's been six months so wow! What an improvement to my quality of life. It has also reduced stress/tension and eased expressiveness in social settings, which was what I was hoping for.

  • Leandra - 14th Oct 2020

    5
    Great for anxiousness

    I originally tried this supplement to treat chronic anhedonia. I don't think it did much for that but it did help with my anxiousness quite a bit. I titrated up to 4g/day but found that too high (headaches), and now take 1g in the AM, and 1g in the PM. This keeps my stress about 40% lower than it was previously. I wish I could buy a bigger bottle!

3 Reviews

  • Undisclosed - 12th Feb 2021

    5
    It worked for me

    I feel this has smoothened out a lot of friction in my mind and given me more control over my thoughts. I used to frequently overthink myself into headaches over the smallest things but that just hasn't happened since. Absolutely not a change I was expecting and something I was cautiously optimistic about, but it's been six months so wow! What an improvement to my quality of life. It has also reduced stress/tension and eased expressiveness in social settings, which was what I was hoping for.

  • Leandra - 14th Oct 2020

    5
    Great for anxiousness

    I originally tried this supplement to treat chronic anhedonia. I don't think it did much for that but it did help with my anxiousness quite a bit. I titrated up to 4g/day but found that too high (headaches), and now take 1g in the AM, and 1g in the PM. This keeps my stress about 40% lower than it was previously. I wish I could buy a bigger bottle!

  • Unknown - 19th Jan 2020

    5
    Sarcosine

    My son started taking this product 3 weeks ago & it helps him tremendously in his clarity & mood.

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