Vitamin D is an essential vitamin that plays a role in a number of important bodily functions and has been known for years to be a significant factor in supporting bone and cellular function. Although many people relate Vitamin D synthesis to sun exposure, Vitamin D was initially found in Cod Liver Oil. Synthesis of Vitamin D2 and D3 are both stimulated by the sun, however, Vitamin D2 (Ergocalciferol) is primarily produced by plants and fungi, whereas Vitamin D3 (Cholecalciferol), is synthesized in the skin through UVB radiation. This is the well-known form of Vitamin D from sun synthesis many people have come to recognize. Modern research has concluded that Vitamin D3 tends to be absorbed better and provides more Vitamin D benefits than other forms of Vitamin D. This is why the best Vitamin D supplement is a Vitamin D3 supplement.
Many people get their natural dietary sources of Vitamin D from fish, milk that has been enriched with Vitamin D, and general sun exposure. However, this is oftentimes not enough, and Vitamin D deficiencies are quite common. In fact, research has shown that the previously recommended daily intake of Vitamin D foods is insufficient for most people. This led to the rise of people taking a Vitamin D supplement for Vitamin D benefits over the years. Many people are already familiar with the various health benefits of Vitamin D which include the support of joint and cognitive function, with additional benefits to metabolic and cardiovascular function. However, fascinating results from recent research revealed that Vitamin D3 benefits to cardiovascular and metabolic function appear to be tied to Vitamin D3 benefits to blood flow.
Conclusions from studies focusing on Vitamin D3 cognition research indicate that taking a Vitamin D3 supplement notably helped support cognitive function compared to groups that were not supplementing with a Vitamin D3 supplement. In addition, results from research across several fields indicated that there was a direct correlation between consuming a Vitamin D3 supplement and cognitive function and that part of this may be due to the potential Vitamin D3 benefits towards supporting balanced inflammation levels.
If that wasn’t enough to make Vitamin D3 such a fascinating supplement, recent research also discovered that Vitamin D is expressed on critical components of immune system function such as B and T cells! This suggests that taking a Vitamin D supplement supports overall immune system function. In fact, both in vitro and in vivo data concluded that Vitamin D promoted immune system function in both humans and animals. Overall it appears that Vitamin D is a no-brainer when it comes to immune system function! Not only is it critical, but Vitamin D is absolutely necessary for our brains and body to function properly!
Most Vitamin D supplements list the dosage in international units (IU), so you may have wondered, what is the vitamin D IU dosage in our Vitamin D3 + K2? The simple answer to this is 5000 IU, but let’s talk about IU’s some more! You may have noticed that we do not list a Vitamin D IU dosage, and this is because the IU system is outdated and the industry is currently moving away from it. In fact, current FDA guidance is moving away from IU dosages for vitamins like D, A and E, and are instead advising for listing dosages in micrograms or milligrams. Measuring vitamin D dosages in micrograms instead of vitamin D IU allows for more transparency and accuracy in vitamin D dosing.
So what exactly is an ‘IU’ and why is the supplement industry moving away from it? International Units were designed to be used to quantify biological effects based on a weight dependant dosage. The need for International Units exists because vitamins like D, A and E can exist in different forms that have varying levels of biological effects. IU accounts for these different levels of biological effects between the various forms of the vitamin, such that a certain weight-based dosage of specific forms of the vitamin can be dosed at different levels to produce the desired biological effects. For example, let’s take a look at Vitamin A, 1 IU of Vitamin A is the equivalent of:
0.3 mcg retinol
0.6 mcg beta-carotene
In this case, IU allows us to dose Vitamin A in different forms while ensuring the desired biological effects. That being said, the actual IU number is arbitrarily set and this is where things start to get a little confusing. For example, 1 IU of vitamin A is not the same as 1 IU of vitamin D. Worse yet, for Vitamin D there is no distinction between the two main forms, D2 and D3, which is why we went with a Vitamin A example above, instead of a specific example for vitamin D. This means that there is no reason to use vitamin D IU doses. Instead, using micrograms coupled with daily value percentages makes a lot more sense for vitamin D. For the other vitamins, like A and E, other systems have been devised that differentiate between the different forms but instead lists microgram doses specified for each different form.
Vitamin K is an essential vitamin and is typically supplemented for its cardiovascular benefits. The two primary forms of Vitamin K are phylloquinones (Vitamin K1) and menaquinones (Vitamin K2). Vitamin K comes in a few different forms that are sometimes referred to as vitamers, and there are several different vitamers within Vitamin K2 that are abbreviated as MK-x. Vitamin K2 MK-7 is one of the more common types of Vitamin K and is the variant most popularly supplemented for Vitamin K benefits. But what is Vitamin K good for? Although Vitamin K benefits to cardiovascular, metabolic, and bone function have been studied for years, Vitamin K wields a fascinating range of Vitamin K benefits that continue to be researched today.
Recent studies have revealed that a Vitamin K2 supplement may help promote cognitive processes as well. Research conducted over the last decade has shown that cognitive function and Vitamin K supplement consumption appear to be directly correlated. One of the unexpected findings from this research was the relationship between Vitamin K and the myelin sheaths of neurons. Animal studies found that a Vitamin K supplement may help promote myelin sheath function and thus support a critical foundation needed for overall cognitive function. Subsequent studies observed a positive correlation between cognitive-based performance tasks and Vitamin K supplementation.
Vitamin K2 Source: Made from Fermented Soy Natto.
Vitamin C is also known as ascorbic acid and is an essential nutrient that is commonly found in fruits and vegetables. Even though many foods contain Vitamin C, Vitamin C supplements are some of the most commonly used supplements today. We used Vitamin C in this formulation to improve the stability of Vitamin K2 and D3. Vitamin K2 and D3 by themselves are prone to oxidation, adding Vitamin C shields them from this kind of degradation.
It’s well known that most Vitamin D3 and Vitamin K2 supplements are typically formulated together, but why specifically formulate Vitamin K and Vitamin D together? In fact, Vitamin K and Vitamin D have a very synergistic relationship with each other and they each help potentiate the other’s benefits! Some of the most notable benefits of these two in combination are their support of cardiovascular and bone function. Research has also shown that these two exhibit cognitive benefits on their own but can be better utilized when supplemented in combination!
Check out our recommended Vitamin D3 + Vitamin K2 stacks that help further amplify Vitamin D3 + Vitamin K2 benefits!
Cognitive Function Stack: Vitamin D3 + Vitamin K2 with Magtein
This combination is a unique and well-rounded stack for supporting overall cognitive faculties with additional support to cellular function!
Immune Function Stack: Vitamin D3 + Vitamin K2 with Immune Defense
Add Vitamin D3 + Vitamin K2 to our comprehensive Immune Defense formula for added support to immune system function!
Cardiovascular Support Stack: Vitamin D3 + Vitamin K2 with Hesperidin
Vitamin D3 + Vitamin K2 paired with Hesperidin is a two-pronged approach to supporting overall cardiovascular function with additional benefits to metabolic function.
As a dietary supplement, take one Vitamin D3 + K2 tablet daily.
To gain more insight, see the Vitamin D3 + Vitamin K2 reviews and experiences below.
Nootropics Depot offers 60ct. and 365ct. jars of high quality Vitamin D3 + Vitamin K2 tablets. Nootropics Depot’s Vitamin D3 + Vitamin K2 tablets have been lab tested and verified for both product purity and identity.
Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.