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Poria, Wolfiporia extensa (Poria cocos), is a fungus in the family Polyporaceae. It is a wood-decay fungus but has a terrestrial growth habit. It is notable in the development of a large, long-lasting underground sclerotium that resembles a small coconut. The sclerotium of Poria cocos has been used in the Chinese pharmacopoeia for thousands of years.
Wolfiporia extensa is a source of a triterpenoid compound, pachymic acid, which has been the object of scientific study based upon the mushroom's role in traditional Chinese medicine. Pachymic acid has been shown in scientific studies to prevent chronic inflammation, by inhibiting phospholipase A2 (PLA2)-induced extravasation. Along with its proven anti-tumor properties, pachymic acid is known to inhibit the Epstein-Barr virus and to inhibit the snake venom phospholipase A2. Pachymic acid has also shown promise in treating chemotherapy-resistant pancreatic cancer, by inducing apoptosis in gemcitabine-resistant pancreatic cancer cells PANC-1 and MIA PaCa-2. Pachymic acid has also shown to inhibit breast cancer cell invasion, through decreasing MMP-9 expression. Thus it may be potentially exploited for use in tumor metastasis intervention.
For more information, see the Wikipedia article on Poria (Wolfporia extensa).
Nootropics Depot has partnered with Nammex to offer these certified Organic whole fruiting body extracts, with not only testing to verify the percentage of active beta-glucans, but verification that starch content is low, and that there are no pesticide residues. One of the biggest controversies in the medicinal mushroom industry today is the use of mycelium on grain extracts. Mycelium is to a mushroom like what roots are to a tree. When grown properly, they will form whole fruiting bodies; which are called mushrooms. However, to save money, most US producers of medicinal mushroom extracts today grow the mycelium on a bed of grain, like rice. To speed up production, and to make the end product cheaper to produce, these manufacturers grind up the mycelium and grain together, before allowing them to form whole fruiting bodies. The issue with that is that mycelium is not a mushroom, just like the roots of a tree are not a tree. The beneficial compounds in these mushroom species are all studied with relation to their fruiting bodies. The FDA even states that mycelium is not allowed to be called "mushrooms." However, many of the biggest brands today thwart that FDA guideline, and put out a cheaply-made, mislabeled, and ultimately ineffective products. They hide this fact by standardizing to "polysaccharides" instead of "β-Glucans." Well guess what shows up as polysaccharides in the traditional testing? Carbohydrates! Yes, the very carbohydrates from the rice used to grow the mycelium is used as a measure of the active ingredient in these substandard extracts. When you are buying one of the major mushroom extracts on store shelves today, you are buying a bunch of ground up rice mixed in with mycelium! It's a scam! This is why we decided to partner with Nammex. We are selling only certified Organic whole fruiting body extracts, which have been tested for not only the active β-Glucans, but to ensure the starch content is low; to prove what you are getting is actual mushroom, not ground up rice. You will know right away how big of a difference it is. You can even go to the store right now, and pick out one of the major mushroom brands. Mix the "mushroom" powder into some water, and ad a drop of iodine. It will quickly turn a dark purple/blue, indicating high amounts of starch. You'll immediately see how big of a scam it is, and just how many "trusted" brands are in on it!
Beta-Glucan (β-Glucan) content: 50%
Product contains either a 30g or 60g jar of Poria (Wolfiporia extensa) mushroom extract.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.