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100% Vegan Lactose Free Gluten Free GMO Free
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100% Vegan Lactose Free Gluten Free GMO Free

Agmatine Sulfate Powder

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label-lactose-free:
true
label-gluten-free:
true
label-gmo-free:
true
label-vegan:
true
label-vegetarian:
true
info-dose:
250mg (Per Serving)
info-dose-timing:
Flexible
info-dose-frequency:
1-2 Times Daily
info-how-to-take:
With Or Without Food
benefits-effect-days:
1-2 Weeks (With Immediate Effects)
page-fact-checked:
false
research-snapshot-summary:
Agmatine sulfate, derived from L-arginine, is involved in protein synthesis. It may support cognitive function, aid in pain management, offer neuroprotective effects, and help prevent oxidative stress by reducing inflammation and protecting mitochond
Dietary Restrictions:
Lactose Free
Dietary Restrictions:
Gluten Free
Dietary Restrictions:
Non-GMO
Dietary Restrictions:
Vegan
Dietary Restrictions:
Vegetarian
Type:
Powders
Type:
Nootropics
Type:
Amino Acids
Type:
Pre-Workout
disable-paypal:
true
lab-testing:
AGSS1021524 | AGSS1021524_250g_signed.pdf
lab-testing:
AGSS1110723 | AGSS1110723_125g_signed.pdf
lab-testing:
AGSS1052324 | AGSS1052324_125g_Signed.pdf
lab-testing:
AGSS1061024 | AGSS1061024_250g_Signed.pdf
$20.99 - $33.99
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Product Usage

Dose Dose

250mg (Per Serving)

Dose Timing Dose Timing

Flexible

How to Take How to Take

With Or Without Food

Dose Frequency Dose Frequency

1-2 Times Daily

Summary

Agmatine sulfate, derived from L-arginine, is involved in protein synthesis. It may support cognitive function, aid in pain management, offer neuroprotective effects, and help prevent oxidative stress by reducing inflammation and protecting mitochond

ATTENTION EUROPEAN CUSTOMERS: Some EU countries consider agmatine a novel food ingredient, and may not allow it through customs. Please look up your country's specific regulations before purchasing.

What is Agmatine Sulfate Powder?

Agmatine sulfate is a biogenic compound derived from L-arginine, a common amino acid involved in the synthesis of proteins. When L-arginine undergoes decarboxylation, a process that results in the removal of a carboxylic acid group, it becomes agmatine sulfate. This compound is stored in the neurons of the brain and released when those neurons are activated. The process of creating and storing Agmatine sulfate sets it apart from its amino acid counterpart. Agmatine sulfate is considered a neurotransmitter or neuromodulator which could explain some of the Agmatine sulfate nootropic effects some people experience. As a nootropic, agmatine sulfate offers a wide range of potential benefits to your brain health and general fitness.

Agmatine Sulfate Benefits and Uses

    • May help support positive emotional outlook*
    • May help promote restful sleep*
    • May help support immune system function*
    • May help promote overall strength and endurance*
    • May help support digestive health*
    • May help promote cognitive function*

Agmatine Sulfate Bodybuilding and Nootropic use

Agmatine sulfate benefits may impact a wide range of organs and systems to potentially improve overall health. The interaction between Agmatine sulfate with nitric oxide and NMDA receptors have been shown to support various elements of cognitive function and overall health. In particular, these findings focused primarily on memory and learning abilities.

Studies on Agmatine sulfate have also shown Agmatine sulfate’s ability to promote healthy levels of oxidation. Part of this ability may come from Agmatine’s ability to limit glutamate activity. High glutamate activity can potentially cause over-excitation in the brain, leading to something known as excitotoxicity. Excitotoxicity leads to degradation of nerve cells as a result of receptors being overactivated.

As far as how this translates to Agmatine sulfate nootropic effects, Agmatine appears to interact with several neurotransmitter systems and pathways. Agmatine appears to interact pretty strongly with glutamate receptors and pathways in particular. Studies have actually shown that Agmatine levels rise in some regions in the brain when learning something. Agmatine even appears to have a significant role in memory formation in these areas. So, taking an agmatine supplement may help promote memory formation events which may as a whole increase cognitive function focused on memory and learning.*

Agmatine has built itself a reputation in the bodybuilding community for its ability to create huge muscle pumps through its Nitric oxide regulation. Nitric oxide is a compound naturally produced in your body that plays a role in cell signaling and communication throughout your entire system. Anecdotally, this enhanced connection also may promote one’s sense recognition and support feelings of well being. Agmatine sulfate is even used as an ingredient in various pre-workouts and “pump” supplements. In fact, it’s quite common to pair a pre-workout with agmatine sulfate and some athletes swear by the agmatine sulfate bodybuilding benefits. 

As if boosting Nitric oxide levels weren’t enough, Agmatine sulfate also appears to support blood flow by acting as a calcium antagonist. Studies have found that this mechanism of action may help soothe and widen blood vessels which may help support overall cardiovascular function. What’s even better, is that Agmatine may help produce lean muscle mass and may even help enhance muscle definition. This makes Agmatine sulfate one of the best muscle pump supplements out there!*

How Agmatine Sulfate May Promote Cognitive Function*

Agmatine sulfate also appears to interact with NMDA glutamate receptors. Once these receptors are activated, they allow positively charged ions to flow through cell membranes. NMDA receptors are also one of the key glutamate receptors involved in regulating memory functions and synaptic plasticity. Synaptic plasticity is important for the ability of signals between nerves to strengthen or weaken over time. A healthy level of synaptic plasticity means signals are more effectively communicated between neurons.

How to take Agmatine Sulfate and Agmatine Sulfate Dosage

As a dietary supplement, take 250mg of Agmatine sulfate 1-2 times daily. 

Agmatine Sulfate Reviews

To learn more, read the Agmatine sulfate reviews and experiences below.

Where to Buy Agmatine Sulfate Powder?

Nootropics Depot offers 125g or 250g jars of high quality Agmatine sulfate powder. Nootropics Depot's Agmatine sulfate has been lab-tested and verified for both product purity and identity.

You may also like Agmatine sulfate capsules

 *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Reviews

  • 5
    One of my #1 recommended supps

    Posted by Brake Janco on 25th May 2023

    I very been taking agmatine for close to 7 years now and keep buying it because it is just that good. I've found agmatine is most effective as a stress reliever. I like large doses of it toward the end of the day when I'm ready to relax, unwind, and process the day. It dramatically enhances and sustains pain relieving effects. This makes it beneficial for acute pain. Many people, myself included, find it can be lousy for focus and attention. I have found that small amounts <250mg can enhance my social interactions and curb being hyper and having disruptive tendencies, such as talking over people and jumping on a tangent. I like to use a little agmatine as a social lubricant. As a pre-workout, I'm not convinced it's the best thing ever. The pump I get at 1500-2000mg makes me feel a lot more fatigued afterward, and it only lasts around 45 mins for me. That's not good for my 2hr long hypertrophy routines. I prefer rhodiola crenulata for lifting as salidroside is excellent at boosting the NO2 pathways while allowing me to maintain focus on working out. If you're getting enough l-arginine in your diet, your body is likely storing enough agmatine to use for lifting. In fact, agmatine gets released in mood-altering amounts after enough cardiovascular activity. It's likely a contributing factor to the "runner's high." I find agmatine to be an invaluable supplement to have on hand, even if you don't intend on using it every day. The flavor is close to neutral and easy to take down. It's quite affordable, too.

  • 5
    Great quality isolate

    Posted by Os on 22nd Feb 2023

    Great quality isolate of this natural product. For me it produces a sense of calm. It stacks well with choline and Hup A.

  • 5
    Agmatine Sulfate powder

    Posted by Brent on 23rd Mar 2022

    Works well for neuropathic pain and sleep.

  • 5
    Agmatine sulfate

    Posted by Haldor Issente on 8th Mar 2022

    Economical in the 250 gmail size. A potentiator for other substances. A pure product. Quite satisfied.

  • 5
    Very Nice

    Posted by Unknown on 8th Jan 2022

    I will repurchase

  • 5
    LOVE THIS STUFF

    Posted by Unknown on 4th Jan 2022

    So far this will remain on the top of my stack for everyday use.

  • 5
    Grade A+

    Posted by Unknown on 3rd Jan 2022

    Wonderful compound right here guys. This stuff is the real deal and I rank it at the top of the list.

  • 5
    Awesome!

    Posted by Unknown on 2nd Jan 2022

    Taking this to get off a 4 year kratom use and it’s working flawlessly. I was taking kratom just to escape the withdrawals. Highly suggest to cut way back on ur kratom dose with this stuff like more than half. I’m on day 5 and I have cut my dose down to 4 grams 4 times a day to 1 gram 3 times a day. Also take magnesium to eliminate my restless leg.

  • 5
    Nice touch

    Posted by blair darby on 18th Nov 2021

    Are use this in combination with polygala Which adds a very nice touch, great clean energy

  • 5
    subtle? yeah right.

    Posted by Rob Haskell on 19th Jun 2021

    I found that this increased my bloodflow. There could possibly be some issues regarding both tolerance and overdosing, but not every workout product was a hit for me. I think you really have to find your sweet spot. I could be off but for me its probably around 300mg, but you have to sort of dose in a "triangle" shape throughout your on-week, in my experience. Lighter at first, then respond to the tolerance, then respect the buildup. It seems to build up short-term. I get nauseous if I overdo it. Anyways Im convinced that this one was a successful hit and if you buy anything else and also not this for working out then youre a whole fool. Start here. And for that, 5 full stars. Im reordering as we speak.

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*Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.