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Beta-ecdysterone | 20-Hydroxyecdysone 50% Capsules

Standardized to 50% 20-hydroxyecdysone for muscle mass, bone health, joint support, and enhanced physical performance.

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Beta-ecdysterone | 20-Hydroxyecdysone 50% Capsules

Standardized to 50% 20-hydroxyecdysone for muscle mass, bone health, joint support, and enhanced physical performance.

(3 Reviews) Write a Review

View All Reviews

Available in multiple forms! Click Here for:
  • Highest Beta-ecdysterone Content
  • Reliable 50% Standardization
  • Lab-Tested Purity & Consistency
  • Supports Muscle & Joint Health

3rd Party Lab Tested & Verified

See Why ND Beta-Ecdysterone Delivers The Highest Bioactives

Updated On: 05/05/2026

$34.99

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Benefits

When You'll Notice Effects

3-4 Weeks

Beta Ecdysterone is a naturally occurring plant steroid that may increase muscle mass and performance, support bone and joint health, and provide neuroprotective benefits by reducing oxidative stress and improving memory.

  • Muscle Mass Muscle Mass
  • Bone Health Bone Health
  • Neuroprotection Neuroprotection
  • Joint Health Joint Health

WHY ND BETA-ECDYSTERONE?

The ONLY beta-ecdysterone standardized to
50% 20-hydroxyecdysone
test

How To Take

Dose
Dose

500mg (One Tablet)

Timing
Timing

Flexible

How to Take
How to Take

With Or Without Food

Frequency
Frequency

1 Time Daily

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  • About Beta-Ecdysterone 50% Tablets

    Beta-Ecdysterone supplement text over purple flowering plant background for natural muscle support.

    Beta-Ecdysterone 50% Capsules deliver plant-based support for muscle growth, bone health, and joint strength through a reliable 50% standardization of 20-hydroxyecdysone from Cyanotis arachnoidea. This versatile phyto-compound supports physical adaptability and daily energy, making it practical for fitness enthusiasts and anyone maintaining an active lifestyle. With just one capsule daily, you can experience benefits that often appear within the first month, seamlessly integrating into any supplement stack alongside other products in our muscle growth category.

    Our Beta-Ecdysterone Story

    We surveyed the beta-ecdysterone market and found inconsistent extracts, unclear standardizations, and products that couldn't deliver on their promises. Too many companies offered weak concentrations or unreliable sourcing, leaving customers uncertain about what they were actually getting. We knew there had to be a better way to harness this promising plant steroid's potential.

    We took a methodical approach: source only from premium Cyanotis arachnoidea, establish a true 50% standardization that we could verify consistently, and subject every batch to rigorous third-party testing. We wanted to create a beta-ecdysterone supplement that would give both serious athletes and everyday wellness enthusiasts confidence in their choice. The result is a product that delivers reliable potency in a simple, once-daily format that integrates smoothly into any routine.

    Benefits

    • Increases Muscle Mass: Beta-ecdysterone supports muscle mass development through its unique plant-based steroid structure, helping users experience improved physical performance during both exercise and everyday activities.
    • Supports Bone Health: This phyto-compound promotes 20-hydroxyecdysone activity that helps maintain strong, resilient bone structure as part of your overall wellness foundation.
    • Supports Neuroprotection: Beta-ecdysterone provides neuroprotective benefits by reducing oxidative stress and supporting healthy memory function through its antioxidant properties.
    • Supports Joint Health: Users often notice improved joint comfort and mobility, with many expressing appreciation for enhanced recovery and reduced stiffness after strenuous activity.

    Beta-ecdysterone's adaptogenic nature makes it an excellent foundation supplement that pairs well with other supplements for muscle growth like creatine or ashwagandha. Many users report a general sense of vitality and increased stamina that makes daily movement feel more effortless, whether you're starting a new workout routine or refining an established regimen.

    Beta-Ecdysterone benefits infographic showing muscle, joint, bone, and neuroprotection claims for nootropic supplement.

    Quality and Standardization

    • 50% Beta-Ecdysterone Standardization: Our capsules are sourced from carefully selected Cyanotis arachnoidea and standardized to deliver a true 50% concentration of beta-ecdysterone, ensuring reliable consistency in every dose.
    • Independent Third-Party Testing: Each batch undergoes rigorous analysis at ISO-accredited laboratories in the U.S., where experts use advanced analytical techniques to confirm both purity and identity.
    • cGMP Manufacturing Standards: We manufacture in cGMP-certified, FDA-registered facilities, providing an additional layer of quality assurance and regulatory compliance.
    • Transparent Analytical Results: In the spirit of "Transparency You Can See," we make analytical results available for verification, so you know exactly what's in every capsule.

    Infographic for Beta-Ecdysterone showing supplement benefits including muscle mass boost, joint health, neuroprotection, and bone support.

    Mechanism of Action

    • Estrogen Beta Receptor Activation: Beta-ecdysterone selectively activates estrogen beta receptors (ERβ) rather than androgenic pathways, promoting muscle protein synthesis and IGF-1 production without typical testosterone-related side effects.
    • Non-Androgenic Pathway: This compound operates through a unique biological mechanism that supports strength and lean muscle gains while avoiding the complications associated with traditional anabolic stimulation.
    • IGF-1 Enhancement: The activation of estrogen beta receptors supports the natural production of IGF-1, a growth factor crucial for cellular regeneration and muscle development processes.
    • Bone and Joint Support: Beta-ecdysterone influences bone density and joint comfort through its receptor interactions, making it particularly beneficial for those engaging in resistance training or intense physical activity.

    Athlete performing barbell squat in gym with Plant Power Real Impact Beta-Ecdysterone muscle growth supplement text.

    Overview of the Science

    Beta-Ecdysterone 50% has captured the attention of researchers in the sports nutrition field, and the emerging science is genuinely exciting. Several controlled studies have shown that beta-ecdysterone can trigger notable muscle hypertrophy, especially when combined with regular strength training [1][2]. What's fascinating is that, instead of taking the usual testosterone pathway like many traditional muscle-building agents, beta-ecdysterone interacts with estrogen beta receptors (ERβ) [1]. Lab studies confirm that this route increases protein synthesis within muscle cells, which is an essential building block for muscle growth and repair [3][4]. Because the process bypasses androgenic (testosterone) signaling, it offers a gentler way to support strength without some of the side effects associated with more aggressive anabolic supplements.

    Scientists have also linked beta-ecdysterone to improvements in bone and joint health. Research suggests it supports healthy cartilage and may encourage autophagy in chondrocytes, which helps keep joints limber and comfortable [5]. Additional studies indicate it supports osteogenic differentiation, promoting healthy bone formation processes [6]. Feedback from the Nootropics Depot community often matches these findings, with customers sharing stories of better flexibility and a smoother recovery routine. The continuously growing body of evidence leaves little doubt: for those looking to build muscle and stay active, Beta-Ecdysterone 50% brings plant-based science and personal experience together in one standout supplement.

    [1] Parr MK, Zhao P, Haupt O, Ngueu Tchoukouegno S, Hengevoss J, Fritzemeier KH, Piechotta M, Schlörer N, Muhn P, Zheng WY, Xie MY, Diel P. Estrogen receptor beta is involved in skeletal muscle hypertrophy induced by the phytoecdysteroid ecdysterone. Molecular Nutrition & Food Research. 2014;58(9):1861-1872.

    [2] Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, de la Torre X, Zimmer P, Kazlauskas R, Goebel C, Botrè F, Diel P, Parr MK. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Archives of Toxicology. 2019;93(7):1807-1816.

    [3] Gorelick-Feldman J, Cohick W, Raskin I. Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells. Steroids. 2010;75(4-5):332-340.

    [4] Gorelick-Feldman J, Cohick W, Raskin I. Phytoecdysteroids increase protein synthesis in skeletal muscle cells. Journal of Agricultural and Food Chemistry. 2008;56(10):3532-3537.

    [5] Tang Y, Mo Y, Xin D, Zeng L, Yue Z, Xu C. β-ecdysterone alleviates osteoarthritis by activating autophagy in chondrocytes through regulating PI3K/AKT/mTOR signal pathway. American Journal of Translational Research. 2020;12(11):7174-7186.

    [6] Gao L, Cai G, Shi X. Beta-ecdysterone induces osteogenic differentiation in mouse mesenchymal stem cells and relieves osteoporosis. Biological & Pharmaceutical Bulletin. 2008;31(12):2245-2249.

    Nootropics Depot Beta-Ecdysterone 500mg tablets with supplement benefits for muscle, joints, bone, and brain health.

    Ingredients

    Beta-Ecdysterone:

    • 20-Hydroxyecdysone from Cyanotis arachnoidea
    • Standardized to 50% Beta-ecdysterone
    • 500mg per serving

    The 50% standardization ensures consistent potency and reliable dosing in every tablet. This high concentration of beta-ecdysterone from Cyanotis arachnoidea provides the active phytoecdysteroid compounds that research suggests may support muscle protein synthesis and physical performance. Nootropics Depot's rigorous standardization process guarantees you receive exactly 250mg of active beta-ecdysterone per 500mg serving, eliminating the variability found in unstandardized extracts.

    Shirtless man using battle ropes in gym with highlights of Beta-Ecdysterone supplement quality, manufacturing, and sustainability.

Trust Through Transparency

Your health matters, which is why we only use the best 3rd party ISO accredited labs and cGMP certified and FDA registered facilities right here in the USA

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Beta-ecdysterone | 20-Hydroxyecdysone 50% Capsules

Beta-ecdysterone | 20-Hydroxyecdysone 50% Capsules

$34.99