Lion's Mane Mushroom Extract Capsules | 500mg | Whole Fruiting Body | Hericium erinaceus

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Lion's Mane mushroom extract (Hericium erinaceus)
Whole Fruiting Body Mushroom
Beta-Glucan (β-Glucan) minimum content: 25%
1:1 Extract
60ct. or 180ct.
60 Servings or 180 Servings
As a dietary supplement, take one 500mg Lion's Mane Mushroom Extract capsule 1-2 times daily.
Store in a cool and dry place. Keep away from direct sunlight and heat.
Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.
Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases. These statements have not been evaluated by the Food and Drug Administration.

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Lion's Mane Mushroom Extract Capsules | 500mg | Whole Fruiting Body | Hericium erinaceus
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This product has been lab-tested and verified for purity and identity.


Why Should I Take Lion’s Mane Mushroom?

Lion’s mane mushroom has built up quite the reputation over the years, and firmly established itself as one of the most sought after natural nootropics! There is a good reason for this, the fruiting bodies of the lion’s mane mushroom are chock full of beneficial compounds, which can help promote cognitive, cardiovascular and immune function.

Our lion’s mane is also unique for the fact that it only utilizes pure fruiting body. This is in contrast to mycelium on grain products which have become more and more popular in the mushroom world over the last few years. Mycelium on grain products can’t even be called mushrooms, because they aren’t actually mushrooms yet at this stage! While mycelium on grain products certainly can contain beneficial compounds, they simply don’t compare to high quality fruiting body lion’s mane. This sentiment is shared amongst many lion’s mane enthusiasts, including ourselves, which is why we have always found it important to provide only high quality fruiting body mushroom products!

What is Lion’s Mane Mushroom?

Hericium erinaceus, or more commonly known as Lion’s Mane Mushroom, is a fully edible mushroom belonging to the tooth fungi family. This mushroom is easily spotted by their long and dangly spines. Just to add to the quirkiness of this mushroom, it is also known as bearded tooth mushroom, hedgehog mushroom, and even pom pom mushroom. The names stem from its unique clusters that look similar to a lion’s mane.

Lion’s Mane Mushroom naturally grows in Europe, Asia and North America on hardwood trees in late summer and fall. This mushroom contains various beneficial polysaccharides, such as beta-glucans, and several terpenoid compounds such as the hericenones and erinacines.

Lion’s Mane Mushroom Extract is standardized to a minimum of 25% Beta-Glucan (β-Glucan).

Lion's Mane Benefits and Uses

    • Promotes cognitive function
    • Promotes immune function
    • Promotes cardiovascular function

The Importance of Fruiting Body Extracts

Mushrooms are quite unique in many ways, and one of the most special things about mushrooms is how they grow. First, spores inoculate a substrate, which then causes mycelium to grow. The mycelium are root-like structures, from which the actual mushroom eventually grows. The mushroom is what we call the fruiting body. It’s quite interesting to note that the mycelium, under the right conditions, can already contain some very unique bioactive compounds. In particular, a now quite legendary compound called erinacine A, is expressed in the mycelium but not in the fruiting body. This finding has been completely taken out of context though, in the mushroom supplements world.

Erinacine A, and other erinacines, do in fact occur in the mycelium of the mushroom. However, this compound is not always present in the mycelium, and is only expressed in high amounts when the conditions are perfect. However, this idea has led to the rising popularity of mycelium lion’s mane products. The issue with this trend is that the mycelium is not being produced properly for this purpose.

In order to cultivate fruiting body lion’s mane, you first have to inoculate a grain based substrate, with spores or even mycelium. These spores then start to form mycelium throughout the substrate. The myceliated substrate is then exposed to fruiting conditions, and the lion’s mane mushroom starts to grow. However, this process takes quite a long time, because lion’s mane is a relatively slow growing mushroom. The process can be cut short though, and this is what the mycelium on grain products do.

These products utilize the same process, they take grain substrate, inoculate it with lion’s mane spores or mycelium, and then they wait for the mycelium to colonize the grain substrate. Once there is a good amount of mycelium, the myceliated substrate is freeze dried and ground up. This means that a significant portion of a product like this, is simply just grains and not actual mushroom. In our opinion, this is simply a convenient shortcut that has been presented as the “next generation” of mushroom supplementation. This simply is not the case however, and all the research on lion’s mane, and the majority of human use of this mushroom, has all depended heavily on the fruiting bodies of the mushroom, not lazily produced mycelium!

What Can Real Fruiting Body Lion’s Mane Do For You?

With our 1:1 lion’s mane product, you get the full spectrum of all the beneficial compounds that are naturally found in lion’s mane. A stand out in this lion’s mane fruiting body product, will be its beta-glucan content, which is quite high at 25%! The beta-glucans within lion’s mane will have very positive effects on overall immune function, while also promoting overall cardiovascular function. These high levels of beta-glucans can only be found in high quality fruiting bodies, which is part of the reason why fruiting body lion’s mane products are highly sought after.

Our 1:1 lion’s mane will also preserve a wide range of terpenoid compounds that naturally occur in the fruiting body. These terpenoid compounds have been shown to have very beneficial effects on cognitive function, which is why lion’s mane has long been regarded as one of the best natural nootropics. Within the 1:1 lion’s mane, these compounds are expressed in a natural balance with all of the other beneficial compounds in lion’s mane, which results in a very nice, full spectrum effect. If however, you are mostly interested in the nootropic effects of lion’s mane, we would suggest checking out the more potent cognition enhancing extract of lion’s mane, our dual water/ethanol 8:1 extract.

Lion's Mane Mushroom Extract Stacks

The Cognitive Stack: Lion's Mane Mushroom Extract + AvailOm® High DHA Capsules

As you may know, fish oil supplements are great for promoting cognitive function but AvailOm High DHA takes it to the next level. DHA in particular is an important fatty acid in the brain, and due to lion’s mane neuroplasticity enhancing effects, availOM high DHA makes the perfect companion to lion’s mane!

The Immune Stack: Lion's Mane Mushroom Extract + Andrographis paniculata Capsules

Looking to support immune function? Then look no further than Lion’s Mane Mushroom and Andrographis paniculata! Andrographis paniculata is also great at balancing inflammation levels, which helps round out the effects profile of lion’s mane mushroom!

The Cardiovascular Stack: Lion's Mane Mushroom Extract + Nobiletin Capsules

Nobiletin is well-known for its incredible cardiovascular support. When combined with Lion’s Mane Mushroom, this is the perfect cardiovascular stack! With additional benefits to metabolic function and balanced inflammation levels, this is not a stack to skip.

Lion's Mane Mushroom Dosage

As a dietary supplement, take one 500mg Lion's Mane Mushroom Extract capsule 1-2 times daily.

Lion’s Mane Mushroom Capsule Reviews

To gain more insight, see the Lion's Mane Mushroom Capsule reviews and experiences below.

Where to Buy Lion's Mane Mushroom Capsules?

Nootropics Depot offers 60ct. or 180ct. jars of certified organic Lion's Mane Whole Fruiting Body Mushroom Capsules. Nootropics Depot's Lion's Mane Mushroom capsules have been lab-tested and verified for both product purity and identity.

You may also like our Lion's Mane Mushroom 1:1 Extract powder

Attention: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

29 Reviews

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  • Dusan - 4th Feb 2023

    High quality. Really helps with cognitive functions.


  • Prakash Gupta - 4th May 2022


    This is an average product in my opinion. As such, it does make you more calm, but if you are used to a normal level of anxiousness to drive your motivation and work, I wouldn’t recommend this. Also, the extract is better than this product in terms of potency

29 Reviews

  • Dusan - 4th Feb 2023

    High quality. Really helps with cognitive functions.


  • Prakash Gupta - 4th May 2022


    This is an average product in my opinion. As such, it does make you more calm, but if you are used to a normal level of anxiousness to drive your motivation and work, I wouldn’t recommend this. Also, the extract is better than this product in terms of potency

  • Marcos Puig - 24th Apr 2022

    Lios mane

    Really good product. It looks and feels really pure

  • Clemence - 4th Mar 2022

    Excellent for Intermittent Fasting entry

    I used to binge eat out of boredom or excess emotions, so I decided to try OMAD intermittent fasting for at least a month to lessen my junk food dependency. I took Lion's Mane alone with a multivitamin, enzymes and a few probiotics with my daily meal and I'm now into my third month without the feeling of dread over not binging anymore. I took a lot of Lion's Mane (about 10 capsules daily) during my first two weeks and my thinking was clear, level-headed and fervently curious about learning creative skills on a whim —EXACTLY what I needed while my body was relearning hunger&full signals. Now I tapered down to just one capsule a day, which helps as a subtle boost during my late morning/early afternoon (my daily meal is a breakfast, so all my supplements begin to release around this time). Mushrooms in general are spectacular in my opinion. They're so synergistic.

  • Abraham Gordillo - 6th Jan 2022

    Good supply

    I was able to use this product to help me regain my smell and taste. I have been taking lions mane for various brands for approximately a year now and in the last month I lost my taste and smell due to infection. I wanted to try this brand to help test the theory that lions mane could help and it did. I am also using their reishi powder.

  • Syl - 29th Dec 2021

    Lion's Mane

    These mushrooms are incredible for language, memory and other cognitive functions, and also to improve move and daily functions. It is proved to increse the myelin cover of neurons in the CNS and to delay dementia in seniors.

  • Bryce - 11th Nov 2021

    The best

    I am a big proponent of natural medicine like therapeutic mushrooms and lions main. If you do a quick Google search on the benefits of lions main, you'll find a plethora of one of wonderful effects. It can help with anxiety and depression it's an anti inflammatory and it can also help prevent you from getting sick as well as more detrimental illnesses. Just take it regularly once a day and your brain / body will thank you!

  • Eve - 15th Aug 2021

    LION"s MANE MUSHROOM caps 500 mg

    I gave it a try not knowing if it was going to work. I have to say that i notice A great improvement in my memory overall after taking it for few months. Thank you!

  • Roy Grimes - 23rd Apr 2021

    Not for me

    From the research I've done, this can be either a miracle supplement or do next to nothing. Unfortunately, I'm in the latter group. After taking it for a month now, I've noticed no change. I will continue taking it, mainly for the beta glucans. I know the quality is good and pure, because I do well with other mushrooms from ND. Cordyceps is my personal favorite.

  • ULISSES MESQUITA - 29th Oct 2020


    I have used this product to sleep and I have obtained good results.

  • Kari Gates - 23rd Jun 2020

    Lions mane

    Great product. I take it everyday. Not too expensive.

  • Michael - 16th Feb 2020


    Not too sure what I was supposed to expect with this product. not really experiencing anything mind blowing

  • Travis - 3rd Feb 2020

    Just what I needed

    Great neurological booster and mood stabilizer. For those of you used to taking doctor prescribe drugs, this is a better solution with no side effects for this particular strain. But do you know it runs more like a low gear tractor rather than a fast race car. The effects are subtle yet powerful. Not to mention Delray of other benefits such as an immune enhancer.

  • Moeenuddin Hashim - 16th Dec 2019

    Mild benefits

    initially i had headaches, but the headaches eased off after the first few weeks. verbal fluency has seen mild, but noticeable improvement, brain fog is slightly better. But I am going to buy this again. Also, in terms of mood, i became more active (less passive), more aggressive and less submissive - but all these changes were mild, and I dont know whether I should attribute these to the mushroom or not.

  • Ian C - 3rd Apr 2019

    Life Saver

    as someone given the diagnosis of an attention disorder and then put on stimulant medication for years, lion’s mane was the only no-side effects supplement to get my brain back on track after dropping the pharmaceuticals while also maintaining my productivity afterward. Great product. I prefer this one over the others sold on this site.

  • wayne - 26th Mar 2019

    stress free

    This product is amazing helps with cognition and it also kept me calm through out the days this is literally like a stress reliever 5 stars

  • JSwizz - 25th Oct 2018

    Great Product

    I use Lions Mane, Red Reishi and Cordyceps together for overall health and immune support. I also give this to my spouse who had chronic sinus infections and would miss a significant amount of time away from work due to illness. Since taking this combo, she hasn't had a sick day in 3 years... Super happy with these products

  • Shawn Medeiros - 19th Sep 2018

    No effects were felt

    no benefits or effects were felt when consumed even at 1000mgs a day for a few weeks .This particular product did nothing for me.

  • Ian - 22nd Mar 2018

    Increased Motivation

    I think the biggest benefit I have noticed from this is the will to get things done when I take it. This is a promising mushroom that I will continue to take. It has many benefits and I am excited to see what else it has to offer.

  • Unknown - 19th Mar 2018

    pretty good

    I know lions mane has a lot of health benefits. Noticed I am slightly less anxious when I take it

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