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Black Seed Extract Powder | Nigella sativa

Standardized to 5% or 10% thymoquinone for immune support, metabolic wellness, and brain health protection.

(18 Reviews) Write a Review

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Black Seed Extract Powder | Nigella sativa

Standardized to 5% or 10% thymoquinone for immune support, metabolic wellness, and brain health protection.

(18 Reviews) Write a Review

View All Reviews

Available in multiple forms! Click Here for:
  • Standardized to 5% or 10% Thymoquinone
  • HPLC Tested for Bioactive Content
  • Supports Immune and Metabolic Function
  • Backed by Centuries of Traditional Use

3rd Party Lab Tested & Verified

See Why ND Black Seed Is The Best

Evidence-Based, Fact-Checked

Updated On: 05/05/2026

$15.99 - $39.99

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Benefits

When You'll Notice Effects

2-3 Weeks (With Immediate Effects)

Black Seed Extract (Nigella sativa) is a plant extract that supports immune function, aids in pain management, promotes metabolic health, and enhances brain health by improving memory and mood while protecting against neurodegeneration.

  • Immune Immune
  • Pain Support Pain Support
  • Metabolism Metabolism
  • Cognition Cognition

WHY ND BLACK SEED EXTRACT?

The ONLY Black Seed Extract standardized to 10% thymoquinone
test

How To Take

Dose
Dose

200mg (Per Serving)

Timing
Timing

Flexible

How to Take
How to Take

With Or Without Food

Frequency
Frequency

1 Time Daily

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  • About Nigella Sativa (Black Seed) Extract

    Nigella sativa black seed extract with 5% and 10% thymoquinone in wooden scoop.

    Black Seed Extract from Nigella sativa is a concentrated powder standardized to contain a minimum of 5% or 10% thymoquinone, the key bioactive compound in these ancient seeds. Black seed supports immune function, promotes healthy metabolic processes, and helps maintain cognitive wellness through its rich profile of essential oils and nutrients.

    Our Black Seed Extract Story

    Black seed's incredible versatility and thousands of years of traditional use across Southern Europe, North Africa, and Southwest Asia drew us to this remarkable botanical. Many suppliers offer basic black seed powders with inconsistent potency, so we developed a standardized extract that delivers reliable levels of thymoquinone, the primary compound responsible for black seed's wellness benefits.

    We focus on the essential oil fraction that makes up only 0.4% to 2.5% of the seed's weight but houses the most bioactive compounds including thymoquinone, dithymoquinone, thymohydroquinone, and carvacrol. By offering both 5% and 10% thymoquinone standardizations, we give you the flexibility to choose the potency that best fits your wellness goals, whether you're new to black seed or looking for a more concentrated option.

    Benefits

    • Supports Healthy Immune Function: The natural antioxidant and antimicrobial components in Black Seed Extract strengthen the body's defenses, helping you feel more resilient during stressful periods or seasonal changes.
    • Supports Pain Management: Black Seed Extract provides gentle, natural support for managing everyday discomfort through its bioactive compounds including thymoquinone and essential oils.
    • Improves Metabolic Function: Black Seed Extract promotes healthy metabolic function and keeps cellular activity running smoothly, supporting your body's natural energy production processes.
    • Supports Brain Health: Regular users report sharper thinking, improved memory, and greater mental clarity, helping you stay more focused at work and present in everyday life.

    Black Seed Extract also supports a positive mood and helps manage stress with its gentle approach to promoting emotional balance. The vitamins, minerals, and essential oils naturally present in Nigella sativa provide nutritional support from within, contributing to overall vitality and helping you maintain an active, engaged lifestyle throughout the years.

    Icons highlight Nigella sativa benefits for cellular, cognitive, metabolic, and immune health.

    Quality and Standardization

    • Standardized Thymoquinone Content: Every batch of our Black Seed Extract is rigorously tested and standardized to deliver either 5% or 10% thymoquinone, ensuring consistent potency and reliable results with each serving.
    • Third-Party Laboratory Testing: We provide complete transparency through third-party test results and detailed sourcing information, so you know exactly what you're getting without any surprises.
    • Quality-First Manufacturing: Our rigorous testing protocols and attention to detail ensure that every batch meets our exacting standards, giving you confidence in your supplement choice.
    • Transparent Process Documentation: We openly share our testing methodology and sourcing practices because we believe you deserve to know where your supplements come from and how we test them.

    Nigella sativa flower and black seeds shown as digestive and immune support supplement.

    Mechanism of Action

    • Thymoquinone Pathway Modulation: The primary bioactive compound thymoquinone interacts with key cellular pathways involved in inflammation regulation and cellular defense mechanisms throughout the body.
    • Antioxidant Response Activation: Multiple aromatic compounds including p-cymene and carvacrol work together to neutralize free radicals and activate the body's natural antioxidant systems, protecting cells from oxidative stress.
    • Immune System Balance: Black seed extract helps modulate cytokine levels and supports T cell activity, coordinating immune responses to maintain optimal immune function.
    • Metabolic Pathway Support: The bioactive compounds influence metabolic processes by supporting healthy lipid profiles and glycemic control through multiple enzymatic pathways.
    • Neuroprotective Support: Essential oils from Nigella sativa provide protective effects for neural tissue, helping maintain healthy cognitive function and stable mood through various brain pathways.

    Bar graph compares thymoquinone levels in Nootropics Depot black seed extract versus competitors.

    Overview of the Science

    Black Seed Extract (Nigella sativa) is backed by a growing base of research highlighting its support for many aspects of general wellness. The main component, thymoquinone, along with related actives like dithymoquinone, thymohydroquinone, p-cymene, and carvacrol, helps promote healthy immune function by supporting balanced cytokine production and encouraging the activity of T cells [1]. These compounds are also recognized for their antioxidant activity, assisting in the neutralization of free radicals and helping to maintain healthy cellular environments.

    Scientific studies have explored Nigella sativa's role in supporting comfortable joint and muscle function, as well as promoting a healthy inflammatory response through its combination of antioxidants and essential oils. There is also evidence that suggests Black Seed Extract can encourage healthy metabolic function, supporting balanced lipid levels and healthy glucose metabolism. The seed's nutritional profile—including vitamins, minerals, and essential oils—works together to foster healthy cellular activity and maintain wellbeing on multiple levels.

    Research continues to investigate its influence on cognitive performance, learning, and memory, with promising early findings around its ability to support healthy mood and mental clarity. Many users also appreciate how these effects contribute to a focus on maintaining overall vitality and general wellness.

    [1] Bin Sayeed MS, Shams T, Hossain SF et al. Nigella sativa L. (Ranunculaceae): A review of its traditional uses, phytochemistry, pharmacology and toxicology. Pak J Pharm Sci. 2012;25(3):553-560.

    Nootropics Depot Nigella sativa capsules support mood, cognition, cellular, and metabolic wellness.


    Click here to read the Research Snapshot

    Ingredients

    Black Seed Extract (Nigella sativa):

    • Nigella sativa seed extract
    • Standardized to minimum 5% Thymoquinone
    • 200mg per serving

    Our Black Seed Extract is standardized to a minimum 5% thymoquinone content, ensuring consistent potency of this key bioactive compound. Thymoquinone is the primary active constituent responsible for many of black seed's wellness benefits, including immune support and antioxidant activity. This standardization level guarantees you receive a reliable dose of the most important compound in every serving, making our extract far more potent and predictable than basic whole seed powders.

    Superior black seeds on a rustic cloth with wooden spoon and sourcing, manufacturing, and lab testing notes.

  • Lab Testing Results / Certificate of Analysis (COA)

The Science

What Our Scientific Board Does

The Process

What Do They Do?

  • Review Product Claims
  • Review Cited Research
  • Suggest Changes to Claims
  • Approves Final Conclusions
See The Process

Overview Of The Scientific Evidence

Our Research Snapshot

What Does The Research Show?

Scientific studies show Black Seed Extract aids immunity, metabolic wellness, and brain health, while supporting memory, mood, and neuroprotection.

Understand The Evidence

Trust Through Transparency

Your health matters, which is why we only use the best 3rd party ISO accredited labs and cGMP certified and FDA registered facilities right here in the USA

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Black Seed Extract Powder | Nigella sativa

Black Seed Extract Powder | Nigella sativa

$15.99 - $39.99