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100% Vegan Lactose Free Gluten Free GMO Free
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100% Vegan Lactose Free Gluten Free GMO Free

OptiNAD+ Capsules

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label-lactose-free:
true
label-gluten-free:
true
label-gmo-free:
true
label-vegan:
true
label-vegetarian:
true
info-dose:
Two Capsules
info-dose-timing:
Morning
info-dose-frequency:
1 Time Daily
info-how-to-take:
With Or Without Food
benefits-effect-days:
3-4 Weeks (With Immediate Effects)
Benefits:
Mitochondria
Benefits:
Physical Energy
Benefits:
Longevity
Benefits:
Sleep
product-summary:
  • Enhances Mitochondrial Function
  • Boosts Metabolic Energy
  • Supports Longevity and Healthspan
  • Helps Regulate Circadian Rhythms
page-fact-checked:
false
research-snapshot-summary:
OptiNAD+ is a supplement that boosts NAD+ levels using a synergistic blend. It supports mitochondrial function, energy metabolism, muscle health, and may enhance healthspan, while also helping regulate circadian rhythms and cellular health.
stack-product:
2731 | Mitochondria
stack-product:
2615 | Longevity
stack-product:
1010 | Sleep
stack-product:
3267 | Physical Energy
atc-product:
2731
atc-product:
2615
atc-product:
1010
atc-product:
3267
cpu-product:
2731
cpu-product:
2615
cpu-product:
1010
cpu-product:
3267
Dietary Restrictions:
Lactose Free
Dietary Restrictions:
Gluten Free
Dietary Restrictions:
Non-GMO
Dietary Restrictions:
Vegan
Dietary Restrictions:
Vegetarian
Type:
Capsules
Type:
Vitamins
Type:
NAD Supplements
disable-paypal:
true
lab-testing:
OPNCS1013024 | OPNCS1013024_caps_60ct_signed.pdf
lab-testing:
OPNCS1021924 | OPNCS1021924_caps_120ct_signed.pdf
lab-testing:
OPNCS1061024 | OPNCS1061024_caps_120ct_Signed.pdf
lab-testing:
OPNCS1120123 | OPNCS1120123_caps_120ct_signed.pdf
lab-testing:
OPNCS1070124 | OPNCS1070124_caps_60ct_signed.pdf
lab-testing:
OPNCS1070924 | OPNCS1070924_caps_120ct_Signed.pdf
$39.99
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Product Usage

Dose Dose

Two Capsules

Dose Timing Dose Timing

Morning

How to Take How to Take

With Or Without Food

Dose Frequency Dose Frequency

1 Time Daily

Summary

OptiNAD+ is a supplement that boosts NAD+ levels using a synergistic blend. It supports mitochondrial function, energy metabolism, muscle health, and may enhance healthspan, while also helping regulate circadian rhythms and cellular health.

Benefits

Time to notice full effects: 3-4 Weeks (With Immediate Effects)

  • Mitochondria Mitochondria
  • Physical Energy Physical Energy
  • Longevity Longevity
  • Sleep Sleep

Build Your Stack

Unlock your full potential by building a supplement stack tailored to your unique goals. Whether you're focused on energy, focus, or overall wellness, we’re here to guide you in creating the perfect combination of supplements to support your journey. Your health, your way—powered by the right stack.

Why Should I Take OptiNAD+?

If you are interested in increasing your NAD+ levels, then look no further than the first highly comprehensive NAD+ stack on the market!* We spent a lot of time formulating the best possible all in one supplement with the purposes of enhancing NAD+ levels, utilizing various different NAD+ precursors such as NMN and Nicotinamide riboside, in addition to synergistic components which make these NAD+ precursors more effective!

If you are not yet familiar with NAD+, then you may be asking yourself, why do I want to take the best supplement on the market for enhancing NAD+ levels? The answer is simple, NAD+ is in every single cell in our bodies, plays a highly important role in energy production and can even help promote healthy aging.* In short, if you want to keep your body and brain running as a well oiled machine, especially as you age, then enhancing NAD+ levels is a great idea!

What is OptiNAD+?

OptiNAD+ is a highly efficacious supplement for enhancing nicotinamide adenine dinucleotide (NAD+) levels, utilizing a very well thought out synergistic blend of ingredients. These are:

  • NMN: Nicotinamide mononucleotide, also known as NMN, is one of the most efficient NAD+ precursors. This is because it is only one step away from NAD+ in the salvage pathway, meaning that conversion to NAD+ is a relatively simple process
  • NR: Nicotinamide riboside, also known as NR, is another high efficiency NAD+ precursor. However, it is not as efficient as NMN because NR first has to convert into NMN, before it can be converted to NAD+. That being said, NR has unique neuroprotective properties that are not seen with NMN!
  • NADH: This is the reduced form of NAD+ and can be absorbed through specific transporters. When NADH becomes oxidized in the body, it rapidly turns into NAD+. This is likely the most efficient route to NAD+, and appears to have significant energizing effects.
  • Apigenin: This unique flavonoid inhibits an enzyme called CD38 which normally breaks down NAD+. By inhibiting CD38, we can ensure that more of the NAD+ we are generating is able to stick around for longer.
  • Quercetin: Similar to apigenin, quercetin also inhibits CD38. However, it also has another trick up its sleeve, which is upregulating the sirtuins. The sirtuins use NAD+ as fuel, and it is thought that the bulk of NAD+ benefits are actually mediated via the sirtuins. Thus, upregulating their levels with quercetin, really helps tie the stack together!
  • Trimethylglycine: Trimethylglycine has recently garnered a lot of attention because it is a very efficient methyl donor. This is important in the context of this highly efficient NAD+ stack because high levels of NAD+ production also mops up a lot of methyl groups. By including a high efficiency methyl donor, we can help replenish these methyl groups.

All of these components were all meticulously hand selected by us and beta-tested before we settled on the final formulation. When we did land at the final formulation, we all proclaimed “this is rocket fuel”, and this is because the increase in energy levels from OptiNAD+ is very palpable!* In fact, switching back to just NMN by itself was quite a let down after using OptiNAD+ for a few weeks because the effects of OptiNAD+ are significantly more robust! OptiNAD+, subjectively speaking, even outcompetes high doses of NMN in the 1,000 mg range. This indicates just how efficient a NAD+ booster OptiNAD+ is!*

OptiNAD+ Benefits & Uses

    • Significantly increases NAD+ levels*
    • Enhances cellular energy*
    • Supports healthy aging*

The Ultimate NAD+ Booster

With the rising popularity of NAD+ precursors, we decided that we needed to make the ultimate NAD+ increasing stack. So now that we have achieved this goal, what can you expect to experience when taking OptiNAD+?

One of the first things people notice when they successfully increase their NAD+ levels, is a unique sense of energy.* It is not particularly stimulating, but it makes you feel like you have more juice in your batteries. It’s a hard feeling to describe, but after your first dose of OptiNAD+, you will understand! This makes OptiNAD+ a great stack to take as a pre-workout, especially when you consider that NADH plays a critical role in ATP production.* We believe that the rapid increase in energy levels with OptiNAD+ can be traced back to its NADH content. Since we need ATP to contract our muscles, it means that more ATP usually results in higher physical capabilities. This is why it would be fantastic as a pre-workout especially on top of a daily creatine monohydrate regimine.

The second thing a lot of people notice when their NAD+ levels have been successfully enhanced is progressively better sleep.* This is due to the fact that NAD+ is a major regulator of our circadian rhythms, and thus higher NAD+ levels appear to help enhance our bodies natural circadian rhythms.* This circadian rhythm link also can help us achieve even more efficient NAD+ synthesis. Not only does NAD+ control circadian rhythms, its very own production is also under circadian control. NAD+ synthesis is highest in the morning, which makes a lot of sense if you think of its energizing effects. This also means that taking OptiNAD+ first thing in the morning would also further help enhance the efficiency of NAD+ synthesis.*

Speaking of lifestyle factors that can influence the efficacy of OptiNAD+, calorie restriction or fasting can also be a great strategy.* This is due to the fact that when we are in a fasted state, our bodies ramp up the production of NAD+. On the flipside, overeating actually slows down NAD+ levels. This means that controlling caloric intake and bodyweight, can have majorly beneficial impacts on NAD+ synthesis. Additionally, this teaches us a lot about what NAD+ can do for our overall health. We’ve all likely heard at this point that fasting can have some major health benefits, and a lot of this can be traced back to increasing NAD+ levels. Thus, taking OptiNAD+ would actually mimic certain aspects of long fasts. However, why pick just one when you can have both? Combining fasting or simply just calorie restriction with OptiNAD+, would be a fantastic way to further increase the efficiency of OptiNAD+!*

Most importantly however, is that NAD+ levels start to plummet as we age. Given the sheer importance of NAD+, especially when you take into account that it is the fuel for the sirtuins, it becomes quite clear that low NAD+ levels are a hallmark of aging. This is what makes OptiNAD+ especially interesting for aging individuals, as it would be able to mitigate this age-related drop in NAD+ levels.* This means that OptiNAD+ can help give you back youthful energy and better sleep! In addition to that, OptiNAD+ would also help increase sirtuin activity, which is also majorly beneficial as we age.*

If you would like to learn more about NAD+, we would highly recommend checking out our podcast on it, which can be listened to below:

In addition to the podcast, we also have a comprehensive blog available about NAD+, which can be found here!

OptiNAD+ Stacks

Cellular Energy Stack: CoQsol-CF® CoEnzyme Q10 Softgels + OptiNAD+

CoQsol-CF, which is a novel formulation of Ubiquinone (CoQ10), also has a great effect on increasing ATP production and overall cellular energy. Combining CoQsol-CF with OptiNAD+ makes for a very high energy stack!*

Longevity Stack: L-Carnosine Capsules + OptiNAD+

Another hallmark of aging is gradually shortening telomere length. Telomeres help protect the ends of our DNA, and as we age this protective telomere cap becomes less and less effective. Taking L-Carnosine however can mitigate this and help lengthen telomeres. Combine this with the longevity effects of OptiNAD+ and you have a very effective longevity stack!*

Circadian Rhythm Stack: Nobiletin Capsules + OptiNAD+

Nobiletin also has a significant positive effect on our circadian rhythms with many users also reporting significantly better sleep quality after consistently supplementing with nobiletin. With this in mind, nobiletin and OptiNAD+ are the perfect pair if you are looking to enhance your circadian rhythms!*

OptiNAD+ Dosage

As a dietary supplement, take two capsules of OptiNAD+ daily.

OptiNAD+ Reviews

To gain more insight, see the OptiNAD+ reviews and experiences below.

Where to Buy OptiNAD+

Nootropics Depot offers 60ct. or 120ct. jars of high-quality OptiNAD+. Nootropics Depot’s OptiNAD+ has been lab-tested and verified for both product purity and identity.

 *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Reviews

  • 3
    Looks better on paper. Good for sleep

    Posted by James on 28th Dec 2023

    The Apigenin in this product is good for sleep I find, which has allowed me to cut out the less productive sleep aid benadryl (DPH) which I had been using for awhile. Other than this, I don't notice any superiority between this and just a regular NMN product. On paper, this product has an ingredient profile, which initially made me think that this will likely be a five star review. It is true that I don't feel like I need to take 1,000-mg of NMN when using this. WIth that said, its not as good as some of the other NMN supps I've taken (which we're themselves combining NMN with other ingredients). Perhaps ND should consider adding in elevATP. Or at least getting out of the mindset or narrow thinking of "this must raise NAD+ levels" in order for it to be well stacked?

  • 5
    Game Changer

    Posted by Kyle Miller on 25th Jun 2023

    This stuff seems to be the real deal. I was taking NMN from another vendor until the Amazon ban, but I'm happy the ban happened because it made me seek out an alternative. I'm 40 years old with a lot mileage, and this stuff real puts the body in healing and growth mode. All around a great supplement that will remain an absolute staple in my stack.

  • 2
    Nothing(nada)

    Posted by dazednconfused on 8th Apr 2023

    I feel absolutely nothing. My brain still feels just as tired and sluggish as it did then. I'm looking for something to help me become more alert and focused. Despite buying the caffeine + nalt, I haven't noticed any effects from them. These supplements don't seem to be doing anything for me. Any suggestions?

  • 4
    Great Sleep

    Posted by William on 3rd Apr 2023

    There were a lot of comments on here citing this as a good sleep supplement. After a month of taking this, I can confirm that my sleep is much more balanced. Along with Magtein, Coriander, and proper sleep hygiene I feel tired at the correct times and am able to fall asleep relatively easily. I do notice a substantial impact on my sleep from this product. Would recommend as sleep effects everything else you do.

  • 4
    Great Product

    Posted by Erik on 11th Dec 2022

    This is a great stacked product. I prefer NR and NMN separately though this is more of a personal preference. The NMN seems the most effective for my particular situation,

  • 5
    OPTINAD+

    Posted by andrew murphy on 31st Oct 2022

    It works!.. 41 year old male who is REALLY crap at getting a proper nights sleep. Usually i would be absolutely exhausted from 6 hours sleep but not when taking these! I've also noticed that i'm less stressed, feeling less of the usual aches and pains! Only been a week but will continue to monitor this (I did not get these effects with just NMN)

  • 5
    Energy Boost

    Posted by Jon on 30th Oct 2022

    Take every morning with CoqSol and seems to give a general energy boost that lasts much of the day (seems much better than NMN/coq combo). Combines nicely with Sabroxy/Skullcap.

  • 5
    Nice longevity/energy stack

    Posted by Slomy on 10th Oct 2022

    Gives a nice energy boost that's different than caffeine. I feel good about taking it. It seems to help my circadian rhythms as I fall asleep better at night when I take this in the morning.

  • 5
    Excellent stack in a capsule (or two)

    Posted by Slim on 4th Oct 2022

    I was really happy when this product was introduced because the individual components are expensive, and I am not confident about creating a balanced stack and prefer to trust the knowledgeable ND product specialists; so this is a cost-effective way to access a great stack. Eperience: I feel a noticeable energy in the mornings when I take OptiNAD+, though after taking it for a while I don't notice the energy spike so much. Without it, however, I don't feel like I'm missing something until skipping multiple days in a row, so maybe there is a residual buildup effect. My partner and I both noticed a decrease in grey hairs, and my partner commented on this without knowing I was taking anything new. I am less stressed than I was when the grey hairs came about, so this could be a coincidence, My circadian rhythm has noticeable improved and I think this is the greatest benefit of this supplement for me. Basically, I feel more naturally ready to sleep at bedtime, even if I had caffeine earlier in the day. Granted, I also bought Horny Goat Weed with this order, but when I dropped the HGW, I still felt that this was the reason my circadian rhythm felt improved, and I noticed a regression when I stopped taking this again for a few days. I also feel that it has given me a bit more capacity for doing extra things doing an extra errand. Overall, very satisfied, and plan to keep taking this, but I cannot 100% guarantee that all the benefits I perceive are from this specific supplement or not placebo, but I am relatively confident as I have dropped this and other things from my stack to confirm.

  • 5
    sustained energy

    Posted by Christian N on 28th Sep 2022

    Sustained energy through the day. Clean feeling, no jitters.

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*Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.