Sabroxy® Tablets | 10% Oroxylin-A
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Benefits
Time to notice full effects: 2-3 Weeks (With Immediate Effects)
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Cognition
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Mood
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Focus
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Memory
Summary
Sabroxy Oroxylin A is a flavone derived from Scutellaria and Oroxylum indicum. It promotes cognitive function by enhancing memory, reversing cognitive impairments, and boosting neurogenesis. It also supports immune function, inflammation, and skin.
Product Usage
100mg (One Tablet)
Morning
Empty Stomach
1 Time Daily
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Sabroxy Tablets General Overview
Sabroxy® Oroxylin-A, is a standardized extract that bridges centuries of traditional wisdom with cutting-edge neuroscience research. This remarkable flavone, derived from the bark of the Oroxylum indicum tree, represents our commitment to bringing you the most effective cognitive support supplements available today. Oroxylum indicum exists widely in India and Southeast Asia and has a robust history of use in Ayurveda, and has been treasured for over 2,000 years for its ability to promote mental clarity and overall wellness. What sets our Sabroxy apart is its precision standardization to deliver exactly 10% oroxylin-A, the primary bioactive compound responsible for the extract's cognitive benefits. Unlike generic Oroxylum extracts that can vary wildly in potency, we ensure every serving delivers consistent, reliable results. Many customers tell us they notice improved focus and mental energy within just a few weeks of starting their routine with Sabroxy. The unique molecular structure of oroxylin-A allows it to cross the blood-brain barrier efficiently, making it particularly effective for supporting cognitive function. This isn't just another brain supplement, it's a scientifically-validated approach to optimizing your mental performance with nature as the guide.

Potential Benefits
Sabroxy works through multiple pathways to support comprehensive brain health, making it one of the most versatile compounds for supporting cognitive function, that we offer. The primary mechanism involves oroxylin-A's ability to enhance dopamine signaling by supporting healthy neurotransmitter activity in the brain. This can create sustained improvements in focus, motivation, and mental energy while maintaining a balanced mood throughout the day. Clinical research shows that participants taking Sabroxy experienced significant improvements in episodic memory, immediate word recall, and numeric working memory compared to placebo. Beyond the potential to support cognitive function, Sabroxy provides remarkable support for balanced inflammation throughout the body. Research demonstrates that oroxylin-A helps regulate key inflammatory pathways, which can indirectly support brain health by promoting healthy neurological function. This dual action on both cognitive function and inflammation makes Sabroxy particularly valuable for long-term brain health maintenance. Many users also report improvements in skin clarity and overall well-being, likely due to the extract's comprehensive wellness-supporting effects. Sabroxy’s ability to potentially support immune function adds another layer of health benefits, making it a truly holistic supplement choice. So, why should you take Sabroxy Oroxylin-A? If you're looking to enhance your focus, memory, and overall cognitive function while supporting healthy inflammation levels throughout your body, Sabroxy could be an excellent addition to your daily routine. Many of our customers have shared how it has helped them feel more mentally sharp and energetic, and we're confident you'll love it too!

Quality and Standardization
Quality and transparency guide everything we do at Nootropics Depot, and Sabroxy is a prime example of this ethos. We source Sabroxy directly from Sabinsa, the developers of the original standardized Oroxylin-A extract, that has been clinically studied, so you get precisely 10% Oroxylin-A in every batch. To further assure purity and accuracy, each batch is sent to independent third-party laboratories for comprehensive analysis. These labs verify the active compound levels of Oroxylin-A, and check for potential contaminants like heavy metals, and residual solvents. We make our Certificates of Analysis available so you can see exactly what’s in your supplement. Our batch-testing policies exceed industry norms because we believe transparency makes a better customer experience. Products are stored under climate-controlled conditions, preserving potency from start to finish. If you want to learn more about our approach to quality, visit our Why ND? page.

Mechanism of Action
What makes Sabroxy special is how oroxylin-A interacts with the brain’s natural signaling systems. It supports healthy dopamine function, maintaining neurotransmitter balance for steady focus and motivation. This makes Sabroxy ideal for those looking for a lift in concentration without overstimulating effects. Oroxylin A modulates GABA-A receptor activity, which may promote mental clarity and alertness, supporting productivity. Even more exciting, oroxylin-A has been shown to boost BDNF (brain-derived neurotrophic factor), a key protein involved in learning, memory, and synaptic growth. By encouraging neurogenesis and efficient brain signaling through pathways like MAPK-ERK and CREB, Sabroxy may help your mind adapt and perform more effectively over time. Sabroxy may also support healthy inflammation management, a factor that scientists now connect with optimal brain and skin health. This is one reason users have noted subtle improvements in overall well-being and skin appearance when adding Sabroxy to their routine.
For deep dive into Sabroxy please visit our article Sabroxy | A Cutting Edge Natural Dopamine Reuptake Inhibitor

Overview Of The Science
Sabroxy stands on a solid scientific foundation that blends traditional use with modern research. Several peer-reviewed clinical trials and laboratory investigations have explored its effect on cognitive wellness. In a double-blind, placebo-controlled study spanning 12 weeks, adults taking Sabroxy demonstrated statistically significant improvements in learning speed, numeric working memory, and verbal recall—all key measures of cognitive function. Importantly, the safety profile recorded in these trials aligns with longstanding traditional use, supporting Sabroxy’s reputation as a safe addition to daily wellness routines.
Preclinical research adds further depth, revealing how oroxylin-A, the principal compound in Sabroxy, helps support brain health through multiple scientific pathways. Oroxylin-A is shown to promote brain-derived neurotrophic factor (BDNF) expression via CREB pathway activation. BDNF is widely recognized for its role in encouraging neural growth, synaptic plasticity, and memory formation. This mechanism helps explain users’ reports of cumulative cognitive benefits, as consistent support of BDNF may foster long-term brain adaptability and resilience. Sabroxy’s influence extends beyond cognition. Recent studies investigate its role in supporting balanced immune and inflammatory responses, measuring widely recognized inflammatory markers such as TNF-α, IL-1β, COX-2, and the NF-κB pathway. In vivo studies found Oroxylin A supports balanced inflammation through regulating SHCBP1. Oroxylin-A’s ability to maintain healthy levels of these biomarkers offers a scientific basis for its holistic benefits, as healthy inflammation profiles are increasingly linked to overall brain and body wellness. Mood support is another intriguing area of research, with laboratory studies highlighting increased BDNF levels, which are associated with emotional balance and mental well-being. Enhanced neuroplasticity helps foster a resilient mindset, better adaptability to stress, and improved everyday mood. Together, these findings underscore why Sabroxy appeals to health-conscious individuals aiming for comprehensive cognitive support.

Lab Testing Results / COAs
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