About Shoden® Ashwagandha Extract Powder

Shoden® Ashwagandha Extract is a clinically-tested, full-spectrum extract standardized to 35% withanolide glycosides, the highest potency available in the market. This premium adaptogen combines carefully selected ashwagandha roots and leaves to deliver superior bioavailability and bioactivity at low doses. Shoden® supports healthy stress levels, promotes restful sleep, and helps maintain cognitive function while supporting overall vitality.

Our Shoden® Story

The ashwagandha market has long been dominated by extracts with modest potencies and incomplete analytical methods. Traditional USP testing only measures 8-10 withanolides out of the 40+ compounds naturally present in ashwagandha, leaving the majority of bioactive components unmeasured and unaccounted for. A significant gap exists between what manufacturers claimed and what consumers actually received.

We partnered directly with Arjuna Natural, the makers of Shoden®, to develop analytical methods that capture the complete withanolide profile using advanced HPLC/UPLC techniques. This collaboration led to the most accurate ashwagandha testing methods in the world, validated by structural elucidation via NMR and certified by ISO-accredited laboratories. Through this rigorous scientific approach, we can now offer Shoden® with its unprecedented 35% withanolide glycoside standardization, delivering a truly full-spectrum ashwagandha extract with consistent potency and comprehensive bioactivity.

Benefits

• Lowers Stress: Supports healthy cortisol levels and helps the body maintain a balanced response to daily stressors through its unique 35% withanolide glycoside content.
• Supports Restful Sleep: Promotes deeper, more restorative sleep quality while reducing non-restorative sleep patterns for better overnight recovery.
• Supports Immune System Function: Strengthens natural immune defense mechanisms through ashwagandha's adaptogenic properties that help maintain overall immune balance.
• Promotes Cognitive Function: Improves mental clarity, focus, and cognitive performance through neuroprotective compounds that support healthy brain function.

Shoden®'s high bioavailability keeps these benefits active in your system for extended periods, with significant withanolide levels detectable in the blood even six hours after supplementation, providing sustained adaptogenic support throughout the day.

Quality and Standardization

• 35% Withanolide Glycoside Standardization: Our Shoden® extract delivers the industry's highest withanolide glycoside content, verified through advanced HPLC/UPLC methods that measure the full spectrum of bioactive compounds.
• Advanced Analytical Testing: We partnered with Arjuna to develop proprietary assay methods that analyze over 40 different withanolides, far exceeding the standard USP method that only tests 8-10 compounds.
• ISO Accredited Lab Verification: Each batch undergoes comprehensive testing at third-party labs including Omnient Labs and Intertek, with withanolides structurally elucidated via NMR for maximum accuracy.
• Full Spectrum Extract Profile: Combines both ashwagandha roots and leaves to create a complete bioactive profile with 21 major peaks visible on chromatographic analysis.
• High Bioavailability Formulation: Maintains significant withanolide glycoside levels in blood plasma for up to six hours, ensuring sustained bioactivity even at low 120mg doses.

Mechanism of Action

• HPA Axis Modulation: Shoden® works by modulating the hypothalamic-pituitary-adrenal axis, helping regulate cortisol production and supporting the body's natural stress response pathways for balanced cortisol supplements.
• GABA-ergic Activity: The withanolide glycosides in Shoden® enhance GABAergic neurotransmission, promoting calming effects and supporting relaxation without sedation through natural neurotransmitter supplements activity.
• Neuroprotective Pathways: Shoden® supports neuronal health by promoting brain-derived neurotrophic factor (BDNF) expression and protecting against oxidative stress damage in neural tissue.
• Immunomodulatory Effects: The extract helps balance immune system function by supporting healthy cytokine production and enhancing the body's natural defense mechanisms against environmental stressors.

Overview of the Science

Clinical research demonstrates that Shoden® Ashwagandha extract significantly reduces stress and cortisol levels in healthy adults [1]. In a randomized, double-blind study, participants taking Shoden® showed marked improvements in stress-related symptoms and cognitive function compared to placebo [1]. Additional studies have confirmed Shoden®'s ability to support healthy sleep patterns, with participants experiencing improved sleep quality and reduced sleep disturbances within just a few weeks of supplementation [2][3]. The extract's unique 35% withanolide glycoside standardization contributes to its superior bioavailability, with significant levels of active compounds remaining in the bloodstream for up to six hours after consumption [4].

Research on cognitive function reveals that Shoden® enhances memory performance and information processing speed in healthy adults [5][6]. Clinical trials have shown significant improvements in both immediate and general memory, with participants demonstrating better attention span and mental clarity. The extract's neuroprotective properties extend to supporting overall vitality and energy levels, with studies documenting improvements in physical performance and reduced fatigue in adults taking standardized ashwagandha extracts [7]. The enhanced bioavailability profile of Shoden® allows for effective results at lower dosages compared to traditional ashwagandha extracts [8].

[1] Gopukumar K et al. Evid Based Complement Alternat Med. 2021;2021:8254344.

[2] Lopresti AL et al. Medicine (Baltimore). 2019;98(37):e17186.

[3] Langade D et al. Cureus. 2019;11(9):e5797.

[4] Rathi P, Kim SK. Curr Ther Res Clin Exp. 2025;103:100805.

[5] Choudhary D et al. J Diet Suppl. 2017;14(6):599-612.

[6] Leonard M et al. Nutrients. 2024;16(12):1813.

[7] Lopresti AL et al. Am J Mens Health. 2019;13(2):1557988319835985.

[8] Rathi P, Kim SK. Curr Ther Res Clin Exp. 2025;103:100805.

Ingredients

Shoden® Ashwagandha Extract:

• Withania somnifera (root and leaf)
• 35% withanolide glycosides by HPLC/UPLC
• 120mg per serving

This precise 35% withanolide glycoside standardization represents a breakthrough in ashwagandha potency measurement. Unlike traditional methods that only detect 8-10 withanolides, our advanced HPLC/UPLC testing captures over 40 different bioactive compounds for the most comprehensive nootropic herbs profile available. The inclusion of both root and leaf material creates a full-spectrum extract that maximizes bioavailability while delivering therapeutic effects at remarkably low doses compared to standard ashwagandha preparations.