Agmatine Sulfate 250mg Capsules

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  • Agmatine Sulfate 250mg Capsules
  • Agmatine Sulfate 250mg Capsules
  • Agmatine Sulfate 250mg Capsules
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Agmatine Sulfate
60ct. or 120ct.
60 Servings or 120 Servings
As a dietary supplement, take one 250mg Agmatine Sulfate capsule 1-2 times daily.
Store in a cool and dry place. Keep away from direct sunlight and heat.
Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.
Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases. These statements have not been evaluated by the Food and Drug Administration.
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What is Agmatine Sulfate?

Agmatine sulfate is a common amino acid derived from L-arginine that’s involved in protein synthesis. When L-arginine undergoes decarboxylation, a process that results in the removal of a carboxylic acid group, it converts into agmatine sulfate. Agmatine sulfate is stored in neurons within the brain and gets released when those neurons are activated.

Agmatine sulfate is regarded as a neuromodulator and neurotransmitter which may explain some of the Agmatine sulfate nootropic benefits some people tend to experience. As a nootropic, Agmatine sulfate offers a diverse profile of potential Agmatine sulfate benefits for brain health and function as well as overall fitness.

Agmatine Sulfate Benefits and Uses

    • May help promote positive emotional outlook
    • May help support restful sleep
    • May help promote immune system function
    • May help promote strength and endurance
    • May help support gastric motility and digestion
    • May help support cognitive function
    • May help promote cardiovascular function

Agmatine Sulfate Bodybuilding and Nootropic use

Agmatine benefits may involve an array of organs and bodily systems to help promote overall health. Agmatine sulfate’s interaction with NMDA and Nitric oxide receptors have been shown to promote several elements of cognitive function and brain health. In particular, these results focused heavily on memory and learning abilities. Research on Agmatine benefits on animals uncovered Agmatine sulfate’s ability to support healthy oxidation levels. It is believed that this may be a result of Agmatine’s capacity to limit glutamate activity. High glutamate activity can potentially induce over-excitation in the brain. This over-excitation is known as excitotoxicity. Excitotoxicity can cause nerve cells to degrade due to being overactivated. 

As far as how this translates to Agmatine sulfate nootropic effects, Agmatine seems to interact with a few neurotransmitter pathways and systems. When it comes to glutamate receptors, studies found that Agmatine appears to act strongly on these receptors and pathways. Research has found that Agmatine levels tend to increase in some regions of the brain when engaged in a learning process. Agmatine even appeared to exert some influence in memory formation in these areas. Taking an Agmatine supplement may help support memory formation events which may increase overall cognitive function with an emphasis on learning and memory. 

Agmatine has also forged a reputation in the bodybuilding community for its ability to create massive muscle pumps via its Nitric oxide regulation. Nitric oxide is a compound that’s naturally produced in our bodies and plays an important role in cell signaling and communication throughout the entire system. Anecdotal reports suggest that this enhanced connection may also promote feelings of well being. Agmatine sulfate is highly utilized as a main ingredient in various pre-workout formulas and “pump” supplements. In fact, it’s very common among bodybuilders to pair a pre-workout with agmatine sulfate. Some athletes swear by the agmatine sulfate bodybuilding benefits. As if boosting Nitric oxide levels and promoting cognitive function weren’t enough agmatine benefits for you, Agmatine sulfate also appears to support blood flow by behaving as a calcium antagonist. Research has found that this interaction may help widen and soothe blood vessels which in turn may support overall cardiovascular function. What’s even better, is that Agmatine may help create lean muscle mass and may even promote muscle definition. This makes Agmatine sulfate one of the best muscle pump supplements out there!

How Agmatine Sulfate May Promote Cognitive Function

Agmatine sulfate also appears to interact with NMDA glutamate receptors. When these receptors get activated, they allow ions with a positive charge to pass through cell membranes. NMDA receptors are also one of the major glutamate receptors involved in regulating synaptic plasticity and memory functions. Synaptic plasticity is important for the ability of signals between nerves to strengthen or weaken over time. A healthy level of synaptic plasticity means signals are more effectively communicated between neurons.

How to take Agmatine Sulfate and Agmatine Sulfate Dosage

As a dietary supplement, take one 250mg Agmatine Sulfate capsule 1-2 times daily.

Agmatine Sulfate Reviews

To gain more insight, read the Agmatine sulfate reviews and experiences below.

Where to Buy Agmatine Sulfate Capsules

Nootropics Depot offers 60ct. or 120ct. jars of high quality Agmatine Sulfate capsules. Nootropics Depot's Agmatine Sulfate has been lab tested for product purity and identity. 

You may also be interested in agmatine sulfate powder.

*Attention: This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.

11 Reviews

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  • Dan - 10th Jan 2020

    Agmatine working great

    No complaints, they work precisely like they are described to work. I’ve noticed that I’m more ‘awake’ when I’ve been taking them. Also more energized.

  • Jon - 31st Jul 2019


    This did nothing for me

11 Reviews

  • Dan - 10th Jan 2020

    Agmatine working great

    No complaints, they work precisely like they are described to work. I’ve noticed that I’m more ‘awake’ when I’ve been taking them. Also more energized.

  • Jon - 31st Jul 2019


    This did nothing for me

  • Justin - 20th Jun 2019

    GREAT Product

    This a very great product! I really recommend this to everyone due to the overstimulation of the NMDA receptor site. This product will change your life, it certainly has mine.

  • Unknown - 10th May 2019

    Mood boost and endurance

    I get a nice mood boost when taking this. I also get better muscle endurance. It's a great one to take before exercise, or just daily.

  • Lane Graham - 28th Dec 2018

    Fast Shipping, Quality product.

    Speedy shipping, arrived earlier than expected. Top quality Agmatine.
    Functions well as a Neuroprotectant.

  • Unknown - 26th Oct 2018

    Great quality

    Maybe more energy, higer libido, but upset stomach

  • Unknown - 10th Mar 2018


    I first ordered agmatine from another online seller, and was disappointed with the results. Nootropics offers a different quality of Agmatine Sulfate, and the results have been much more promising. I take this supplement once every 12 hours. I am thrilled that this supplement is working. I will be sharing this information with my colleagues, friends, and the medical professionals treating me. Thank you for offering such a wonderful quality of supplements.

  • Bralexon - 1st Dec 2017

    Best Overall Nootropic Supplement Available

    This is the best supplement available period. It does a lot of wonderful things, and Nootropics Depot always delivers the best highest purity supplements with super quick shipping!

    I find that Agmatine does many really good things for me:

    1. Feeling of calm or peace for about 2-4 hours
    2. Reduction of tolerance to almost everything
    3. Potentiates almost everything
    4. Increased "pumps" at the gym - just feels like a larger blood rush to the muscles.

  • Unknown - 3rd Sep 2017

    Good product

    My intended use was for athletic performance. It definitely increases blood flow to muscles in response to training, similar to arginine alpha ketoglutarate. The decrease in pain threshold was odd, but not unbearable. I would recommend only taking on workout days about 30 minutes to 1 hour prior to the start of exercise.

    I take other nootropics so it would be hard to isolate any mental benefits from this alone.

  • Unknown - 16th Jul 2017

    some benefits on attention, mood/ works better than others

    Seems to be more effective than other nootropics.
    Agmatine sulf is not promoted much but produces better results than some promoted nootropics on areas of attention & mood.
    Needs to be taken about 2-3 weeks to notice effects.
    Apparantly it is highly bioavailable so its absorbed well.

  • nick - 11th May 2017

    high quality agmatine sulfate

    Nootropics Depot provides great quality products and I trust them for that. From my experience it is great for pumps in the gym anywhere from 500-1000mg. Also, if you use sparingly, gives a great feeling of overall well being in the same dosage. Supposedly lowers tolerance to certain herbs or drugs, but does not work as well as abstinence for some time in that regard.