DHEA is a fantastic supplement for those looking to enhance their overall hormone profile, with a particular focus on testosterone. This is because DHEA is only two steps away from testosterone in the process of steroidogenesis, which is the primary biosynthetic pathway used for testosterone synthesis. By taking DHEA, you can “feed” the process of steroidogenesis with a testosterone precursor, thereby driving more testosterone synthesis.
DHEA levels tend to drop as we age, and by extension, testosterone levels also start to decline. Due to this, DHEA is particularly popular amongst older individuals looking to restore their testosterone levels. However, in younger individuals looking to optimize their testosterone levels, especially in conjunction with testosterone boosting supplements like Tongkat Ali, DHEA can also produce very beneficial effects! However, you need to be careful with the dose. Most DHEA on the market is dosed very high, but it actually appears that lower doses may be the more appropriate way to dose DHEA. With this in mind, we kept our dose purposely low at 5 mg.
Dehydroepiandrosterone (DHEA) is an androgen hormone which is crucial for the synthesis of testosterone. DHEA is one of the intermediary steps in the process of steroidogenesis which starts with cholesterol and eventually yields testosterone. Another important hormone in this process is Pregnenolone, however, DHEA is much further downstream from pregnenolone and due to this may have a more direct effect than pregnenolone. That being said, we find that we get the best benefits from combining both pregnenolone and DHEA, like we have recently showcased quite successfully with our optimized Cistanche tubulosa stack, CistaMAX, which contains both pregnenolone and DHEA!
The benefits of DHEA are quite clear when we consider its place in the process of steroidogenesis. It’s only two steps away from becoming testosterone, and thus, supplementing with low doses of DHEA can help nudge the process of steroidogenesis in the right direction, towards testosterone synthesis. That being said, DHEA also has some of its own tricks up its sleeve. For example, DHEA acts as an agonist at the elusive Sigma-1 receptor. Agonism of the Sigma-1 receptor by compounds such as DHEA has shown mood and cognition boosting effects! In women, DHEA also appears to have a generally positive effect on the ovaries, and due to this, DHEA may help promote female fertility.
Steroid hormone Synthesis Stack: DHEA + Pregnenolone
Both DHEA and pregnenolone play crucial roles in the process of steroidogenesis, and many people have noted that combining DHEA and pregnenolone produces the best overall effects. We totally agree with this, and we personally often combine both DHEA and pregnenolone for the most comprehensive overall effects profile.
Mood Stack: DHEA + Shoden
Taking a DHEA supplement is not the only way in which we can increase our DHEA levels, because certain botanicals, such as ashwagandha, also have the ability to increase DHEA levels. In fact, the makers of Shoden have shown in a human clinical study that shoden was able to significantly enhance the levels of DHEA-S (one of the metabolites of DHEA). Thus, combining Shoden with DHEA, should have additive effects!
Cognition Stack: DHEA + OmegaTAU
DHEA is an important neurosteroid that has a significant positive impact on our cognitive function, and we find that its subtle nootropic effects stack very nicely with the nootropic effects of our take on the Mr. Happy stack, OmegaTAU!
Fertility Stack: DHEA + OptiNAD+
DHEA produces positive effects on the ovaries, and due to this, can help promote female fertility. NAD+ is also very important for protecting important cells of the ovaries, such as oocytes. Due to this, the combination of DHEA with an NAD+ booster such as OptiNAD+, could produce beneficial effects on women’s fertility.
As a dietary supplement, take 1 tablet daily.
To gain more insight, see the DHEA reviews and experiences below.
Nootropics Depot offers 120ct or 365ct bottles of high-quality DHEA. Nootropics Depot’s DHEA has been lab-tested and verified for both product purity and identity.
| *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. |
